scholarly journals Influence of growth rate and iron limitation on the expression of outer membrane proteins and enterobactin by Klebsiella pneumoniae grown in continuous culture.

1986 ◽  
Vol 165 (2) ◽  
pp. 353-356 ◽  
Author(s):  
J M Lodge ◽  
P Williams ◽  
M R Brown
2021 ◽  
Vol 12 ◽  
Author(s):  
Jie Zhu ◽  
Tao Wang ◽  
Liang Chen ◽  
Hong Du

Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae (cKP), with hypermucoviscosity and hypervirulence, causing community-acquired infections, including pyogenic liver abscess, pneumonia, meningitis, and endophthalmitis. It utilizes a battery of virulence factors for survival and pathogenesis, such as capsule, siderophores, lipopolysaccharide, fimbriae, outer membrane proteins, and type 6 secretion system, of which the former two are dominant. This review summarizes these hvKP-associated virulence factors in order to understand its molecular pathogenesis and shed light on new strategies to improve the prevention, diagnosis, and treatment of hvKP-causing infection.


1998 ◽  
Vol 42 (7) ◽  
pp. 1850-1852 ◽  
Author(s):  
Luis Martínez-Martínez ◽  
Isabel García ◽  
Sofía Ballesta ◽  
Vicente Javier Benedí ◽  
Santiago Hernández-Allés ◽  
...  

The intracellular accumulation of norfloxacin and pefloxacin inKlebsiella pneumoniae was evaluated. The roles of lipopolysaccharide, capsule, and outer membrane proteins were not important for the intrabacterial accumulation of fluoroquinolones in isogenic strains with known outer membrane alterations. In fluoroquinolone-resistant clinical isolates also expressing GyrA alterations, an active efflux leading to decreased accumulation of the drugs enhanced their resistance to these agents.


2011 ◽  
Vol 42 (2) ◽  
pp. 467-469
Author(s):  
Lívia Érika Carlos Marques ◽  
Danielle Ferreira de Oliveira ◽  
Márcia Maria Mendes Marques ◽  
Ana Raquel Araújo da Silva ◽  
Carlucio Roberto Alves ◽  
...  

1986 ◽  
Vol 35 (2-3) ◽  
pp. 255-260 ◽  
Author(s):  
Anita C. Wright ◽  
Linda M. Simpson ◽  
Kathleen Richardson ◽  
David R. Maneval ◽  
James D. Oliver ◽  
...  

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