Novel conformational peptide antigen which simulates an immunodominant epitope of the 2nd extracellular loop of β1-adrenoreceptor: Computer simulation, synthesis, spatial structure

2013 ◽  
Vol 39 (6) ◽  
pp. 588-599 ◽  
Author(s):  
R. Sh. Bibilashvili ◽  
M. V. Sidorova ◽  
A. S. Molokoedov ◽  
Zh. D. Bespalova ◽  
E. V. Bocharov ◽  
...  
Author(s):  
D. S. Tceluiko

The paper explores the mechanisms of digital imitation of traditional tools for designing private gardens in China, the Cultivation Garden in Suzhou, in particular. New graphic-analytical model is proposed. Various approaches are considered for space as an integral structure. Both domestic and foreign literature in the field is investigated, and mathematical tools are selected to analyze the planning structure. The graphical definition of the architecture is given, the areas of its application are considered. An analogy is drawn between the graphicanalytical model and traditional Chinese tools and techniques for the space formation. The graphic-analytical model of the Cultivation Garden is proposed and investigated, and new planning schemes are then suggested. The relevance of the work lies in the use of new tools and techniques for analyzing the spatial structure of historical objects and new design solutions. The aim of this work is to study the graphic-analytical model of the Cultivation Garden, describe the main stages of its development.The following approaches are used: the analysis of the literature in the field; photographs and measurements of the Cultivation Garden; computer simulation; digital structural analysis; generative design method.The generating mechanism in the form of a script in Rhinoceros (Grasshopper) is examined in detail. The process of creating a garden plan is shown. The analysis and generation tool are given together with their disadvantages. A further research into finalization of the script is required for visual representation of the results obtained.


2016 ◽  
Vol 19 (6) ◽  
pp. 731-737
Author(s):  
N. V. Ivanisenko ◽  
I. N. Lavrik ◽  
V. A. Ivanisenko

1988 ◽  
Vol 44 (3) ◽  
pp. 129-136 ◽  
Author(s):  
Hidehiko Okabe ◽  
Haruki Imaoka ◽  
Atsuo Shibuya ◽  
Hitoshi Akami ◽  
Noboru Aisaka ◽  
...  

1967 ◽  
Vol 31 ◽  
pp. 45-46
Author(s):  
Carl Heiles

High-resolution 21-cm line observations in a region aroundlII= 120°,b11= +15°, have revealed four types of structure in the interstellar hydrogen: a smooth background, large sheets of density 2 atoms cm-3, clouds occurring mostly in groups, and ‘Cloudlets’ of a few solar masses and a few parsecs in size; the velocity dispersion in the Cloudlets is only 1 km/sec. Strong temperature variations in the gas are in evidence.


Author(s):  
Kiyomichi Nakai ◽  
Yusuke Isobe ◽  
Chiken Kinoshita ◽  
Kazutoshi Shinohara

Induced spinodal decomposition under electron irradiation in a Ni-Au alloy has been investigated with respect to its basic mechanism and confirmed to be caused by the relaxation of coherent strain associated with modulated structure. Modulation of white-dots on structure images of modulated structure due to high-resolution electron microscopy is reduced with irradiation. In this paper the atom arrangement of the modulated structure is confirmed with computer simulation on the structure images, and the relaxation of the coherent strain is concluded to be due to the reduction of phase-modulation.Structure images of three-dimensional modulated structure along <100> were taken with the JEM-4000EX high-resolution electron microscope at the HVEM Laboratory, Kyushu University. The transmitted beam and four 200 reflections with their satellites from the modulated structure in an fee Ni-30.0at%Au alloy under illumination of 400keV electrons were used for the structure images under a condition of the spherical aberration constant of the objective lens, Cs = 1mm, the divergence of the beam, α = 3 × 10-4 rad, underfocus, Δf ≃ -50nm and specimen thickness, t ≃ 15nm. The CIHRTEM code was used for the simulation of the structure image.


2019 ◽  
Vol 3 (6) ◽  
pp. 723-729
Author(s):  
Roslyn Gleadow ◽  
Jim Hanan ◽  
Alan Dorin

Food security and the sustainability of native ecosystems depends on plant-insect interactions in countless ways. Recently reported rapid and immense declines in insect numbers due to climate change, the use of pesticides and herbicides, the introduction of agricultural monocultures, and the destruction of insect native habitat, are all potential contributors to this grave situation. Some researchers are working towards a future where natural insect pollinators might be replaced with free-flying robotic bees, an ecologically problematic proposal. We argue instead that creating environments that are friendly to bees and exploring the use of other species for pollination and bio-control, particularly in non-European countries, are more ecologically sound approaches. The computer simulation of insect-plant interactions is a far more measured application of technology that may assist in managing, or averting, ‘Insect Armageddon' from both practical and ethical viewpoints.


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