Colorectal Carcinoma Growth Inhibition by Dietary Care Combined with Probiotic Intervention through Targeting NRP2 Expression

2021 ◽  
Vol 500 (1) ◽  
pp. 354-359
Author(s):  
Shanshan Li ◽  
Ting Chen
Keyword(s):  
Colorectal Carcinoma ◽  
Growth Inhibition ◽  
Probiotic Intervention

scholarly journals Growth inhibition effects of ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid on colorectal carcinoma cells and colon carcinoma-bearing mice

2016 ◽  
Vol 13 (4) ◽  
pp. 3525-3532 ◽  
Author(s):  
HUA YE ◽  
QIONG WU ◽  
MENG GUO ◽  
KEFENG WU ◽  
YINGNIAN LV ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Growth Inhibition ◽  
Colon Carcinoma ◽  
Carcinoma Cells

scholarly journals Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1

1996 ◽  
Vol 315 (3) ◽  
pp. 767-774 ◽  
Author(s):  
Bruno SCHNYDER ◽  
Harald LAHM ◽  
Gaëtane WOERLY ◽  
Nicolas ODARTCHENKO ◽  
Bernhard RYFFEL ◽  
...  
Keyword(s):  
Growth Factor ◽  
Colorectal Carcinoma ◽  
Growth Inhibition ◽  
Tyrosine Phosphorylation ◽  
Carcinoma Cell ◽  
Carcinoma Cells ◽  
Insulin Receptor Substrate ◽  
Receptor Complex ◽  
Factor I ◽  
Carcinoma Cell Lines

Induction of growth inhibition in human colorectal carcinoma cell lines by interleukin (IL)-4 and IL-13 was associated with the neophosphorylation of a 170 kDa cellular protein, identified as insulin receptor substrate-1 (IRS-1) by immunoprecipitation. Tyrosine phosphorylation of IRS-1 was also induced by insulin and insulin-like growth factor I. Sublines of colorectal carcinoma cells unresponsive to growth modulation by IL-4, IL-13 or insulin-like growth factor I-induced growth did not phosphorylate IRS-1. A functional, multimeric IL-4 receptor complex was present on all carcinoma cell lines with a subunit composition of 65 kDa, 75 kDa and the previously characterized 130 kDa band as demonstrated by affinity cross-linking with 125I-labelled IL-4. The 65 kDa subunit is novel whereas the 75 kDa band represents the common IL-2 receptor γ-chain. The novel 65 kDa receptor was present as a double band and bound primarily 125I-labelled IL-13. The present study demonstrates the involvement of a novel chain other than the γ-chain in the receptor complexes of IL-4 and IL-13 and post-receptor tyrosine phosphorylation of IRS-1. The association of IRS-1 with growth inhibitory signals in carcinoma cells suggests a novel mechanism of tumour growth control.

Growth inhibition of human colorectal-carcinoma cells by interleukin-4 and expression of functional interleukin-4 receptors

1994 ◽  
Vol 59 (3) ◽  
pp. 440-447 ◽  
Author(s):  
Harald Lahm ◽  
Bruno Schnyder ◽  
Josiane Wyniger ◽  
Zita Borbenyi ◽  
Aysim Yilmaz ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Growth Inhibition ◽  
Carcinoma Cells ◽  
Interleukin 4 ◽  
Human Colorectal Carcinoma

Diagnosis of invasion depth in early colorectal carcinoma by pit pattern analysis with magnifying endoscopy

2001 ◽  
Vol 13 (s1) ◽  
pp. S2-S5 ◽  
Author(s):  
Shinji Tanaka ◽  
Ken Haruma ◽  
Shinji Nagata ◽  
Shiro Oka ◽  
Kazuaki Chayama
Keyword(s):  
Colorectal Carcinoma ◽  
Pattern Analysis ◽  
Magnifying Endoscopy ◽  
Pit Pattern ◽  
Invasion Depth ◽  
Early Colorectal Carcinoma
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