The glutathione system in the subcellular fractions of developing rat brain and liver

2017 ◽  
Vol 11 (4) ◽  
pp. 266-271 ◽  
Author(s):  
O. V. Galkina ◽  
A. A. Bakhtyukov ◽  
M. O. Akhmetshin ◽  
V. M. Prokopenko ◽  
N. D. Eshchenko
Author(s):  
Koichiro Shimomura ◽  
Shoji Yahara ◽  
Yasuo Kishimoto ◽  
Joyce A Benjamins

1972 ◽  
Vol 50 (2) ◽  
pp. 186-189 ◽  
Author(s):  
M. R. V. Murthy ◽  
A. D. Bharucha

The level of DNA polymerase activity per tissue in the soluble fraction (NS) of rat brain nuclei underwent a twofold increase during the first 2 weeks after birth and then declined steeply over the next 10 weeks to a value only one-third ofthat in the newborn. In contrast to brain, the enzyme activity per liver increased continuously from birth up to 12 weeks of age (10-fold). The DNA contents of these tissues appear to be quantitatively related to the DNA polymerase activities in the respective NS fractions. These preparations did not phosphorylate thymidylate to TTP, but could convert the other three complementary deoxynucleotides to the triphosphate level. This latter activity was highest in the NS fraction of the newborn rat brain and decreased drastically with growth. In the corresponding fraction of liver, the activity remained relatively stable throughout the growth period tested.


1969 ◽  
Vol 115 (5) ◽  
pp. 1051-1062 ◽  
Author(s):  
N. L. Banik ◽  
A. N. Davison

1. Subcellular fractions and myelin were isolated from developing and adult rat brain. 2. Measurements of chemical composition and enzyme activities indicate the presence of a second myelin-like fraction mainly in the brain of developing rats. 3. This membrane fraction has a different lipid composition from myelin, but resembles myelin in its content of phosphohydrolase and aminopeptidase activity. 4. It is suggested that the second myelin-like fraction may be a submicrosomal contaminant or it may be derived from oligodendroglial plasma membrane during myelinogenesis.


1984 ◽  
Vol 20 (1) ◽  
pp. 263-269 ◽  
Author(s):  
E. Kitraki ◽  
M.N. Alexis ◽  
F. Stylianopoulou

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