scholarly journals POS0711 SUICIDAL BEHAVIOUR IN SLE PATIENTS: A SYSTEMATIC LITERATURE REVIEW

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 605.1-605
Author(s):  
A. Kyriakou ◽  
A. Chatzittofis ◽  
K. Parperis
Keyword(s):  
Suicidal Ideation ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Suicidal Behavior ◽  
Suicidal Behaviour ◽  
Renal Involvement ◽  
Clinical Manifestations ◽  
Case Series ◽  
Neuropsychiatric Lupus ◽  
Damage Indices

Background:Previous studies have demonstrated that SLE patients have a higher risk of suicidal behaviour, including suicidal ideation, attempt and complete suicide (1,2). Data describing the SLE patients’ clinical characteristics and risk factors of suicidal behaviour are lacking.Objectives:To determine the magnitude of suicidal behaviour among SLE patients and to examine predictors associated with suicidal behaviour.Methods:According to the PRISMA guidelines, we conducted a systematic literature review of the online databases, PubMed/Medline, EMBASE, and Web of Science, from inception to December 2020 (Figure 1). Full-text original articles that examined the relationship between SLE patients with suicidal behaviour were eligible for our review. Two reviewers independently review articles to assess eligibility using the Newcastle-Ottawa Scale and the Joanna Briggs Institute tools. Systematic reviews, metanalysis, narrative review, case reports, case series, including less than 10 patients and conference abstracts, were excluded.Results:Of the 64 articles identified, 22 were relevant to the study question; cross-sectional (n=8) and prospective cohorts (n=6) were the most frequently retrieved studies. Among the 27106 SLE patients with SLE, 802 had suicidal behaviour (2.9%), and of those, 87.9% were female. Suicide attempt occurred in 573/802 (71.4%) and complete suicide in 18/802 (2,3%). Major depressive disorder (MDD) was the most frequently reported coexisting psychiatric condition associated with suicidal behavior, followed by psychosis and social phobia. Several clinical manifestations were linked to suicidal behaviour, particularly neuropsychiatric lupus, mucocutaneous, renal involvement and serositis. Further, high scores in disease activity and damage indices were associated with suicidal behaviour.Conclusion:Suicidal behavior in SLE patients was associated with MDD, NPSLE, active disease and damage. Awareness of these findings can guide clinicians to recognize suicide behavior promptly and prevent suicide attempts.References:[1]Hajduk A, Nowicka-Sauer K, Smoleńska Ż, Czuszyńska Z, Zdrojewski Z. Prevalence and correlates of suicidal thoughts in patients with neuropsychiatric lupus. Lupus. 2016 Feb;25(2):185-92. doi: 10.1177/0961203315603136.[2]Buji RI, Abdul Murad NA, Chan LF, Maniam T, Mohd Shahrir MS, Rozita M, Shamsul AS, Mohamad Hussain R, Abdullah N, Jamal R, Nik Jaafar NR. Suicidal ideation in systemic lupus erythematosus: NR2A gene polymorphism, clinical and psychosocial factors. Lupus. 2018 Apr;27(5):744-752. doi: 10.1177/0961203317742711.Figure 1.A PRISMA chart describing the inclusion/exclusion processDisclosure of Interests:None declared

scholarly journals AB0763 IGG4-RELATED CORONARY PERIARTERITIS: SYSTEMATIC LITERATURE REVIEW WITH OUR CASE SERIES

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1408.3-1409
Author(s):  
T. Ito ◽  
S. Fukui ◽  
T. Kanie ◽  
T. Nakai ◽  
G. Kidoguchi ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Imaging Modality ◽  
Clinical Manifestations ◽  
Case Series ◽  
Wall Thickening ◽  
Circumflex Artery ◽  
Left Circumflex Artery ◽  
Coronary Ct

Background:Coronary periarteritis is one of the clinical manifestations of IgG4-related disease. It can cause serious conditions such as angina and ruptured aneurysms. Therefore, it is important to recognize the clinical and radiological characteristics, which was little known.Objectives:We report four patients with IgG4-related coronary periarteritis with a systematic literature review.Methods:We identified four patients with IgG4-related coronary periarteritis at the St. Luke’s International Hospital in Tokyo, Japan from 2014 to 2020. A systematic literature review was conducted for English articles on IgG4-related coronary periarteritis cases with a full text or abstract available. We summarized patient demographics, IgG and IgG4 titers, the site and morphological type of coronary lesion, and other organ involvements.Results:Our 4 cases and 38 cases identified by the literature review were assessed. Coronary artery lesions were detected by a coronary CT in all but two cases. Wall thickening was the most common type of the lesion. Moreover, there were 32 (76.1%) patients with other organ involvements. The commonest other lesion was peri-aortitis in 21 (50.0%) patients. In cases with peri-aortitis, IgG and IgG4 titers were significantly higher than those without peri-aortitis (IgG4; 1540 [705.0, 2570.0] vs 246.0 [160.0, 536.3]; p = 0.001, IgG; 3596.5 [2838.3, 4260.0] vs 1779.0 [1288.3, 1992.8]; p =0.040). In addition, 15 (71.4%) patients of them had three or more IgG4 related organ involvements.Conclusion:Coronary CT was a useful imaging modality for the diagnosis of IgG4-related coronary periarteritis, and wall thickening was the most common lesion. Moreover, about half cases coexisted with peri-aortitis. Peri-aortitis and other organ involvements should be screened in those with higher IgG and IgG4.Table 1.Characteristics of our cases and the literature review cases.RCA: right coronary artery, LAD: left anterior descending artery, LCx: left circumflex arteryDisclosure of Interests:None declared

scholarly journals Apatinib in recurrent anaplastic meningioma: a retrospective case series and systematic literature review

2020 ◽  
Vol 21 (7) ◽  
pp. 583-589 ◽  
Author(s):  
Yong Wang ◽  
Wenke Li ◽  
Nianliang Jing ◽  
Xiangji Meng ◽  
Shizhen Zhou ◽  
...  
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Case Series ◽  
Retrospective Case ◽  
Anaplastic Meningioma ◽  
Retrospective Case Series

scholarly journals Personality and Suicidal Behavior in Old Age: A Systematic Literature Review

2018 ◽  
Vol 9 ◽  
Author(s):  
Anna Szücs ◽  
Katalin Szanto ◽  
Jean-Michel Aubry ◽  
Alexandre Y. Dombrovski
Keyword(s):  
Literature Review ◽  
Old Age ◽  
Systematic Literature Review ◽  
Suicidal Behavior

scholarly journals 45: Essure removal for presumed device side-effects: A case series and systematic literature review

2016 ◽  
Vol 214 (4) ◽  
pp. S491
Author(s):  
C. Arora ◽  
S. Shazly ◽  
S. Laughlin ◽  
M. Hopkins ◽  
D. Breitkopf ◽  
...  
Keyword(s):  
Side Effects ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Case Series

A Systematic Literature Review of Technologies for Suicidal Behavior Prevention

2018 ◽  
Vol 42 (4) ◽  
Author(s):  
Manuel A. Franco-Martín ◽  
Juan Luis Muñoz-Sánchez ◽  
Beatriz Sainz-de-Abajo ◽  
Gema Castillo-Sánchez ◽  
Sofiane Hamrioui ◽  
...  
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Suicidal Behavior

scholarly journals 119. Nocardia Bacteremia Is Almost Always Associated with Immune Compromise or an Intravascular Device: Single-Center Case Series and Systematic Review of the Literature

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S90-S90
Author(s):  
Eloise Williams ◽  
Adam W Jenney ◽  
Denis W Spelman
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
Systematic Literature Review ◽  
English Language ◽  
Case Series ◽  
Blood Cultures ◽  
Single Center ◽  
Intravascular Device ◽  
Pubmed Database ◽  
All Cause Mortality

Abstract Background Nocardia bacteremia is a rare but important phenomenon, with previous studies describing a 50% mortality rate. We undertake a single-center review and the largest systematic review of Nocardia bacteremia performed over the past 20 years. Methods A single-center review of cases of Nocardia bacteremia was performed using hospital microbiology records from January 1, 2010 to December 31, 2017. A systematic literature review was also performed to identify cases of Nocardia bacteremia described in the English language literature between January 1, 1999 and December 31, 2018 using the NCBI PubMed database and snowballing from citations of relevant publications. Results Single-center case series: Four cases of Nocardia bacteremia are described. Three patients had an intravascular device in situ prior to the onset of Nocardia bacteremia and three patients were immunocompromised; one patient had both risk factors. Systematic literature review: A systematic review identified 50 publications that described 85 cases with sufficient patient data to be reviewed in detail. Including the 4 cases described in our institution, 89 cases of Nocardia bacteremia were included in the analysis. The median age was 57 years [interquartile range (IQR) 42–68] and 69% were male. Eighty-two percent of cases were immunocompromised and 38% had endovascular devices. Pulmonary infection was the most common concurrent site of clinical disease (66%), followed by central nervous system (25%), pleural (17%) disease, and endocarditis (11%). Blood cultures were the only positive microbiological specimen that isolated Nocardia in 45% of cases. Median incubation time to blood culture positivity was 4 days [IQR 3–6]. Thirty-day all-cause mortality was 24% and overall all-cause mortality was 42%. Conclusion Four new cases of Nocardia bacteremia are described. Isolation of Nocardia from blood cultures is rare but represents serious infection with high associated overall mortality. Nocardia bacteremia is most frequently identified in immunocompromised patients and those with intravascular devices. Disclosures All authors: No reported disclosures.

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