G164(P) Fetal Echocardiography use to determine congenital heart disease recurrence rate in cases with family history: four years retrospective study from single tertiary centre in Egypt

Objectives. To evaluate the recurrence of congenital heart disease (CHD) in pregnant women with familial risk who had been referred for fetal echocardiography.Material and Methods. 1634 pregnancies from 1483 women with familial history of CHD in one or more relatives were studied. Fetal cardiologic diagnosis was compared with postnatal findings at 6 months or at autopsy.Results. Total recurrence rate of CHD was 3.98%, 4.06% in single familial risk, 2.9% in double, and 5% in multiple risk. It was 3.5% in case of one previously affected child; 4.5% with 2 children; 5.2% with the mother alone affected and 7,5% with father alone affected and 3.5% with a single distant relative. Exact concordance of CHD was found in 21.5% and a partial concordance in 20% of cases.Conclusions. Our data show a higher recurrence rate of CHD than previously published data and high relative risk ratios compared to normal population.

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Congenital Heart Disease-A Retrospective Study of 156 Cases in Senegal

Journal of Pediatrics Perinatology and Child Health ◽

10.26502/jppch.74050050 ◽

2020 ◽

Vol 04 (04) ◽

Author(s):

Idrissa Basse ◽

Amadou L Fall ◽

Amadou Sow ◽

Mouhamed C Léye ◽

Alain Affangla ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Retrospective Study ◽

Congenital Heart

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Fetal echocardiography: Recognition and intrauterine treatment of fetal cardiac problems and prenatal diagnosis of congenital heart disease.

The Kurume Medical Journal ◽

10.2739/kurumemedj.34.147 ◽

1987 ◽

Vol 34 (3) ◽

pp. 147-163

Author(s):

NORIKO RIKITAKE ◽

HIROHISA KATO ◽

ON TOYODA ◽

KAZUSHIGE SUZUKI ◽

OSAMU INOUE ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Prenatal Diagnosis ◽

Congenital Heart ◽

Fetal Echocardiography ◽

Intrauterine Treatment

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A retrospective study of judicial encounters of young adults with congenital heart disease

Journal of Health Psychology ◽

10.1177/1359105315578301 ◽

2016 ◽

Vol 21 (10) ◽

pp. 2409-2419 ◽

Cited By ~ 1

Author(s):

Theresa M Malpas ◽

Susan M George ◽

Jillian M Kaisar ◽

Dorothy J Radford

Keyword(s):

Congenital Heart Disease ◽

Young Adults ◽

Heart Disease ◽

Retrospective Study ◽

Congenital Heart

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Conotruncal Malformation Complex: Examples of Possible Monogenic Inheritance

PEDIATRICS ◽

10.1542/peds.63.6.890 ◽

1979 ◽

Vol 63 (6) ◽

pp. 890-893

Author(s):

Marvin E. Miller ◽

David W. Smith

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Family History ◽

Congenital Heart ◽

Recurrence Risk ◽

Strong Family History ◽

Cardiac Defects ◽

Monogenic Inheritance ◽

Congenital Cardiac Defects ◽

Malformation Complex

Two families are described in which there is possible monogenic inheritance of congenital cardiac defects within the spectrum of faulty conotruncal septation (CTS). Evidence for a genetic control of conotruncal septation arises from genetic and embryologic studies of similar defects in the Keeshond dog model, the excess of sibship pairs with conotruncal septation defects in sibship pairs with congenital heart disease, and previously reported pedigrees of families with multiple affected individuals with conotruncal septation defects. It is suggested that in the small number of cases of congenital cardiac defects in which there is a strong family history for CTS defects, a higher recurrence risk should be considered rather than the usual polygenic recurrence risk of 3% that is usually given in such situations.

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Cardiac involvement in genetic disease

Oxford Textbook of Medicine ◽

10.1093/med/9780199204854.003.1611_update_001 ◽

2010 ◽

pp. 2834-2841

Author(s):

Thomas A. Traill

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Family History ◽

Genetic Disease ◽

Congenital Heart ◽

Cardiac Involvement ◽

Atrioventricular Canal ◽

Marfan's Syndrome ◽

Atrioventricular Canal Defect ◽

History Of

Many clinicians find themselves faced, from time to time, with a patient who has a family history of a known disorder, such as Marfan’s syndrome, or who has noncardiac features that suggest a syndrome. Down’s syndrome—25 to 50% have congenital heart disease, most characteristically atrioventricular canal defect....

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Diagnostic value of fetal echocardiography for congenital heart disease – A single center study

Indian Heart Journal ◽

10.1016/j.ihj.2017.09.079 ◽

2017 ◽

Vol 69 ◽

pp. S76

Author(s):

P.R. Mankame ◽

A. Phaterpekar ◽

A. Bafna ◽

H.C. Shah ◽

C.P. Lanjewar ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Congenital Heart ◽

Fetal Echocardiography ◽

Diagnostic Value ◽

Single Center ◽

Single Center Study ◽

Center Study

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Prevalence of Congenital Heart Disease: A Single Center Experience in Southwestern of Iran

Global Journal of Health Science ◽

10.5539/gjhs.v8n10p288 ◽

2016 ◽

Vol 8 (10) ◽

pp. 288 ◽

Cited By ~ 2

Author(s):

Pedram Nazari ◽

Mohammad Davoodi ◽

Mohammad Faramarzi ◽

Mohammad Bahadoram ◽

Nozar Dorestan

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Family History ◽

Congenital Heart ◽

Septal Defect ◽

Cross Sectional Study ◽

Concomitant Disease ◽

Single Center ◽

Cross Sectional ◽

Single Center Experience

BACKGROUND: Congenital heart disease (CHD) refers to complex abnormalities that affect the structure or function of the heart due to embryonic defects. There is little accurate statistical data about prevalence, incidence and frequency in many developing countries such as Iran. The aim of this study was to evaluate the frequency of CHD in patients who were referred to the Department of Pediatric Cardiology in a large single-center in Southwestern of Iran.METHODS: This is a retrospective, cross-sectional study. Patients with various cardiac malformations were each investigated separately. A check list was used to collect information. It was comprised of three parts; demographic characteristics, Patient’s birth details and maternal data.RESULTS: The frequency of ventricular septal defect (VSD), atrial septal defect (ASD) and tetralogy of fallot (TOF) were 125 (28.47%), 48 (10.93%) and 41(9.3%) respectively. Family history was reported in 26(11.1%) cases. Down syndrome, skeletal anomaly and hematological anomaly were the most common co-anomalies. Parental consanguinity was 48.7%.CONCLUSIONS: Present study showed that VSD was the most common CHD subtype followed by family history, familial marriage, extra cardiac anomalies (ECAs), birth weight, and maternal concomitant disease. But there was a controversial relationship between birth order and drug history in CHD.

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