scholarly journals Meningovascular syphilis causing recurrent stroke and diagnostic difficulties: a scourge from the past

2018 ◽  
pp. bcr-2018-225255 ◽  
Author(s):  
Sunil Munshi ◽  
Senthil K Raghunathan ◽  
Ileana Lindeman ◽  
Ashit K Shetty
2000 ◽  
Vol 6 (S2) ◽  
pp. 642-643
Author(s):  
CD Humphrey

“Emergence” of infectious disease agents in humans, domestic animals and wildlife during the past 20 years has been widely described. Perception of emergence derives largely from the application of improved identification methods, including refinements in molecular, serologic, and microscopy technologies that enable researchers to monitor species migration with greater sensitivity. The reality of emergence comes from shifts in genetic profiles and from influences of ecological changes often brought about by human interventions designed for economic or quality-of-life gains, and ecologic management. CDC has frequent involvement with many outbreaks caused by various infectious disease agents, some of which may be considered emerging. Notable unusual agents include filoviruses (Fig. 1) and hantaviruses (Fig. 2). More typically encountered agents include caliciviruses (Fig. 3) and influenza viruses (Fig. 4). Recently, threats of national and international bioterrorism have added to CDC's responsibilities for prompt identification of infectious agents.


2010 ◽  
Vol 04 (02) ◽  
pp. 202-207 ◽  
Author(s):  
Alper Alkan ◽  
Emel Bulut ◽  
Omer Gunhan ◽  
Bora Ozden

Objectives: The purpose of this clinical study was to identify a clinical and histopathological relationship between verrucous hyperplasia, verrucous keratosis, and verrucous carcinoma.Methods: We evaluated 12 patients who had developed oral verrucous carcinoma in the past 10 years in a follow-up study. In this study, the diagnostic criteria included clinical and histopathological features of the lesions. Each lesion was examined by a single oral pathologist.Results: All the patients were diagnosed with verrucous carcinoma following excisional biopsy. One patient was diagnosed with verrucous hyperplasia and another with verrucous keratosis in their initial histological findings. Mandibular, posterior alveolar crest, and retromolar trigone were the most affected sites (41.6%), followed by the buccal mucosa (16.6%), the palate (16.6%), the floor of the mouth (16.6%), and the lip (8.3%). No patients had evidence of recurrence after treatment.Conclusions: Verrucous hyperplasia, verrucous keratosis, and verrucous carcinoma may not be distinguished clinically or may coexist, resulting in diagnostic difficulties. It should be kept in mind that verrucous hyperplasia may also develop from leukoplakic lesions, and it may transform into verrucous carcinoma or squamous-cell carcinoma, acting as a potential precancerous lesion. (Eur J Dent 2010;4:202-207)


2017 ◽  
Vol 37 (03) ◽  
pp. 383-390 ◽  
Author(s):  
R. Joundi ◽  
G. Saposnik

AbstractThe risk of recurrent stroke after transient ischemic attack (TIA) is high. In the past 10 years, TIA has increasingly been recognized as a medical emergency. Health systems have adapted toward rapid evaluation, investigation, and secondary prevention in patients with presumed TIA and minor stroke, and the significant benefits in reducing recurrent stroke and mortality have been borne out in several landmark studies. Various scores have been developed and debated to better risk stratify patients with TIA for hospitalization or urgent referral. However, scoring systems face challenges in identifying all patients with high-risk etiologies such as atrial fibrillation and carotid stenosis, and therefore require further refinement before widespread use. Further challenges include the role of advanced imaging in TIA, and ensuring rapid access to specialist care for all patients. In the absence of definitive risk stratification methods, the authors conclude that all patients with suspected TIA and minor stroke should be assessed and treated on an urgent basis, ideally through rapid outpatient referral programs.


Stroke ◽  
2020 ◽  
Vol 51 (6) ◽  
pp. 1656-1661
Author(s):  
Neal S. Parikh ◽  
Abhinaba Chatterjee ◽  
Iván Díaz ◽  
Alexander E. Merkler ◽  
Santosh B. Murthy ◽  
...  

Background and Purpose— Patients who continue to smoke after a stroke face a higher risk of recurrent stroke. While several effective drugs for smoking cessation became available over the past 2 decades, whether active smoking has decreased among stroke survivors is unknown. We, therefore, evaluated trends in active smoking among stroke survivors during this period. Methods— We performed trends analyses using cross-sectional data collected every 1 to 2 years from 2 US health surveys spanning 1999 to 2018. In the National Health and Nutrition Examination Survey (NHANES) and the Behavioral Risk Factor Surveillance System (BRFSS) survey, participants were asked about prior stroke and active tobacco smoking. In NHANES, serum cotinine levels were available as a secondary measure of active smoking. We used multivariable logistic regression models for survey data to assess trends in active smoking among participants with and without prior stroke. Results— Among 49 375 participants in NHANES during 1999 to 2016 and 3 621 741 participants in BRFSS during 2011 to 2018, the prevalence of stroke was ≈3%. The overall prevalence of active smoking among stroke survivors was 24% in NHANES and 23% in BRFSS. Among individuals without prior stroke, the odds of smoking decreased over time in both NHANES (odds ratio, 0.95 per 2 years [95% CI, 0.93–0.96]) and BRFSS (odds ratio, 0.96 per year [95% CI, 0.96–0.96]). In contrast, there was no decrease in smoking among stroke survivors in NHANES (odds ratio, 1.00 [95% CI, 0.93–1.07]) or BRFSS (odds ratio, 0.99 [95% CI, 0.98–1.004]). Results were consistent in secondary analysis using biochemical ascertainment of active smoking in NHANES and in sensitivity analyses accounting for potential demographic changes in stroke epidemiology. Conclusions— In contrast to the general population, the prevalence of active smoking among stroke survivors has not decreased during the past 2 decades.


2012 ◽  
Vol 65 (11-12) ◽  
pp. 496-501 ◽  
Author(s):  
Slobodanka Petrovic ◽  
Radmila Ljustina-Pribic ◽  
Branislavka Bjelica-Rodic ◽  
Gordana Vilotijevic-Dautovic ◽  
Svetlana Cegar

Introduction. The number of people suffering from tuberculosis has increased rapidly in the whole world over the past three decades. The classical age distribution of disease has also changed. According to the epidemiological data the number of pregnant women having tuberculosis has also risen with the resulting increase in the incidence of perinatal tuberculosis. Pregnancy and Tuberculosis. The presentation of tuberculosis in pregnancy varies. The effects of tuberculosis on pregnancy depend upon various factors: site and extent of the disease, nutritional status and immune status of mother, concomitant diseases, stage of pregnancy when the treatment started and others. A delay between the onset and diagnosis occurs regularly. Treatment response, time to clearance of bacilli from sputum, and prognosis are similar to non pregnant women. Prinatal tuberculosis. Perinatal tuberculosis is extremely rare if the mother is effectively treated in pregnancy, but disease is usually fatal if untreated. Diagnosis of perinatal tuberculosis is very often problematic and difficult. The reason of this is the fact that the initial manifestations of disease are nonspecific and may be delayed. In practice, congenital and early neonatal infections have almost the same mode of presentations, treatment and prognosis. Epidemiological data on the active tuberculosis in mother or some other family member are of the utmost importance in diagnoing tuberculosis. Differences in immune responses in the fetus and neonate add to the diagnostic difficulties already recognised in young children. Tuberculin tests are negative in at least 75% of cases. Conclusion. If the condition is recognized and treated according to existing tuberculosis protocols, the outcome is favourable.


2009 ◽  
Vol 2 (3) ◽  
pp. 51-54 ◽  
Author(s):  
Satyawati Mohindra ◽  
Amanjit K Bal ◽  
Jagvir Yadav

ABSTRACT Purpose The authors intend to present a case of osteosarcoma of the maxilla which presented like a mucocele, a previously unreported phenomenon. Patients and methods Clinical features, radiology, histopathological findings and endoscopically managed osteosarcoma of the maxilla are presented. Diagnostic difficulties and previously reported diagnostic dilemmas related to osteosarcomas of the maxillary sinus are discussed. Results The patient has been on regular follow-up for the past 10 months, and is free from any local or systemic disease. Conclusion Though osteosarcoma of the maxilla is a rare tumor about 6.5% of all osteosarcomas1, patients tend to be in the late-third to mid-fourth decades of life, a high index of suspicion and aggressive management can reduce the morbidity that goes with the management of this condition.


2021 ◽  
Vol 429 ◽  
pp. 118907
Author(s):  
Ignacio Del Pino De Laguno ◽  
Carmen De Rojas Leal ◽  
Lina Carazo Barrios ◽  
Carlos De La Cruz

Author(s):  
Giuliano Ascani ◽  
Giada Albani ◽  
Giuliano Ascani ◽  
Michele Romano ◽  
Noemi Mazzone ◽  
...  

Schwannomas (neurilemmomas) are infrequent, benign mesenchymal neoplasms that pose considerable preoperative diagnostic difficulties. Schwannomas of the submaxillary gland are even less common, with only few cases reported in the literature to date. The present study describes a male with a right submaxillary tumor for the past 9 years; the histopathological study diagnosed schwannoma - no preoperative evaluation having been able to establish the diagnosis.


1967 ◽  
Vol 31 ◽  
pp. 405
Author(s):  
F. J. Kerr

A continuum survey of the galactic-centre region has been carried out at Parkes at 20 cm wavelength over the areal11= 355° to 5°,b11= -3° to +3° (Kerr and Sinclair 1966, 1967). This is a larger region than has been covered in such surveys in the past. The observations were done as declination scans.


1962 ◽  
Vol 14 ◽  
pp. 133-148 ◽  
Author(s):  
Harold C. Urey

During the last 10 years, the writer has presented evidence indicating that the Moon was captured by the Earth and that the large collisions with its surface occurred within a surprisingly short period of time. These observations have been a continuous preoccupation during the past years and some explanation that seemed physically possible and reasonably probable has been sought.


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