scholarly journals Spontaneous splenic rupture in a patient with infectious mononucleosis

2019 ◽  
Vol 12 (9) ◽  
pp. e230259
Author(s):  
Charlotte Ruth Baker ◽  
Sid Kona
Keyword(s):  
Epstein Barr Virus ◽  
Splenic Rupture ◽  
Rare Complication ◽  
Young Female ◽  
Pleuritic Chest Pain ◽  
Diagnostic Challenge ◽  
Barr Virus ◽  
Ebv Infection ◽  
Epstein Barr ◽  
Atraumatic Splenic Rupture

We present a case of spontaneous, atraumatic splenic rupture secondary to Epstein-Barr virus (EBV) infection, in a young, female patient. Splenic rupture is a rare complication of EBV infection, but is associated with the highest mortality. Additionally, this case illustrates the diagnostic challenge in a patient presenting in atypical manner, with only left-sided pleuritic chest pain, and lacking any of the classical tonsillitis symptoms associated with EBV infection.

scholarly journals P-O12 Atraumatic Splenic Rupture Secondary to Concurrent Cytomegalovirus and Epstein Barr Virus Infection

2021 ◽  
Vol 108 (Supplement_9) ◽  
Author(s):  
Catherine McCollum ◽  
Khurram Khan ◽  
Dhruv Sahni ◽  
David Bell ◽  
David Chong
Keyword(s):  
Epstein Barr Virus ◽  
Splenic Rupture ◽  
Sudden Onset ◽  
Cmv Infection ◽  
Barr Virus ◽  
Ebv Infection ◽  
Life Threatening ◽  
History Of ◽  
Epstein Barr ◽  
Atraumatic Splenic Rupture

Abstract Background Infectious Mononucleosis (IM) is a common viral illness among adolescents and young adults. While most cases are self-limiting, a small number of patient can develop life threatening complications, such as atraumatic splenic rupture (ASR). This is a rare but serious sequelae, and the commonest cause of associated mortality. While Epstein Barr Virus is commonly associated with IM, concurrent infection of cytomegalovirus (CMV) and EBV is rarely reported.  Both infections are associated with splenomegaly, however this is usually mild and very rarely results in ASR. Methods We present the case of an immunocompetent nineteen year old male who underwent emergency splenectomy for ASR secondary to concurrent EBV and CMV infection. He presented to the Emergency Department with a five hour history of severe, sudden onset left upper quadrant pain preceded by coughing fit. He reported a one year history of incidental splenomegaly and recent positive monospot test in community. Computerised tomography (CT) of abdomen and pelvis confirmed splenic rupture with large haemo-peritoneum and large sub-capsular haematoma. He was haemodynamically unstable and underwent laparotomy and splenectomy. Results Intraoperative findings included two litres of intraperitoneal blood and large spleen with sub-capsular haematoma; approximately seventeen centimetre diameter and weighed nine hundred and seventy grams. Pathology showed features of non-specific lymphoid hyperplasia. Serum virology confirmed high levels of CMV on polymerase chain reaction with low levels of EBV detected. Virology screening was incidentally repeated post discharge and at this time was consistent acute EBV infection. No alternative cause for splenic rupture or pre-existing splenomegaly has been identified. Conclusions The serology results in this case confirm acute CMV infection with most likely concurrent EBV infection. While we cannot confidently identify which virus caused splenic rupture in this case, ASR is a life threatening condition and an important differential in patients presenting with sudden onset LUQ pain and shock. Splenectomy remains the treatment of choice in haemodynamically unstable patients.

scholarly journals Acute Acalculous Cholecystitis Associated with Epstein–Barr Infection: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Konstantinos Ntelis ◽  
Dimosthenis Mazarakis ◽  
Apostolos Sapountzis ◽  
Dimitra Zissi ◽  
Sophia Sparangi ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Rare Complication ◽  
Relevant Literature ◽  
Young Patients ◽  
Acalculous Cholecystitis ◽  
Acute Acalculous Cholecystitis ◽  
Barr Virus ◽  
Ebv Infection ◽  
Rare Manifestation ◽  
Epstein Barr

The most common cause of acute cholecystitis (ACC) is cholelithiasis. Acute acalculous cholecystitis (AAC) is well documented in the literature related with critical illness, but viral causes such as cytomegalovirus (CMV) and Epstein–Barr virus (EBV) have also been reported. We present a rare manifestation of EBV infection, reporting a case of a 15-year-old female suffering from acute acalulous cholecystitis, and we review the relevant literature. Clinicians should be aware of this rare complication of EBV infection and properly exclude it in young patients with cholecystitis.

scholarly journals Epstein–Barr Virus-Induced Acute Hepatitis, Pancreatitis, and Pneumonitis in a Young Immunocompetent Adult: A Case Report

2021 ◽  
Author(s):  
Elias Fiani ◽  
Rafca Challita ◽  
Hanaa Badawaki ◽  
Khaled Soukarieh ◽  
Melissa Kyriakos Saad ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
Rare Complication ◽  
Human Herpesvirus ◽  
B Cell Lymphoma ◽  
Herpesvirus Type ◽  
Barr Virus ◽  
Ebv Infection ◽  
Human Herpesvirus Type ◽  
Epstein Barr

Epstein–Barr virus (EBV) is a common herpes virus (human herpesvirus type 4) that usually manifests as infectious mononucleosis or persists asymptomatically for life. EBV can also be associated with different types of malignancy such as T cell lymphoma, B cell lymphoma, Hodgkin lymphoma, and oropharyngeal squamous cell and nasopharyngeal carcinoma. Pneumonia is a very rare complication of EBV infection, but it has been reported to occur even in the absence of mononucleosis. This article highlights the case of 35-year-old female who developed acute pancreatitis and acute respiratory failure related to EBV infection. The patient progressively recovered on antiviral therapy and steroids.

scholarly journals Epstein-Barr Virus-induced Jaundice

2020 ◽  
Vol 4 (1) ◽  
pp. 69-71
Author(s):  
Jessica Herold ◽  
Felipe Grimaldo
Keyword(s):  
Biliary Obstruction ◽  
Epstein Barr Virus ◽  
Rare Complication ◽  
Liver Function Tests ◽  
Advanced Imaging ◽  
Barr Virus ◽  
Ebv Infection ◽  
Common Diagnosis ◽  
Epstein Barr ◽  
Made In

Infectious mononucleosis is primarily caused by Epstein-Barr virus (EBV) and is a common diagnosis made in emergency departments worldwide. Subclinical and transient transaminase elevations are a well-established sequela of EBV. However, acute cholestatic hepatitis is a rare complication. EBV infection should be considered as part of the differential diagnosis in patients with an obstructive pattern on liver function tests without evidence of biliary obstruction demonstrated on advanced imaging.

scholarly journals Acute Kidney Injury Complicated Epstein-Barr Virus Infection in Infancy

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Gamze Ozgurhan ◽  
Mustafa Ozcetin ◽  
Aysel Vehapoglu ◽  
Zeynep Karakaya ◽  
Fatih Aygun
Keyword(s):  
Acute Kidney Injury ◽  
Epstein Barr Virus ◽  
Early Recognition ◽  
Rare Complication ◽  
Kidney Injury ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Ebv Infection ◽  
Serological Examination ◽  
Epstein Barr

Infectious mononucleosis is an acute lymphoproliferative disorder caused by the Epstein-Barr virus (EBV) and seen most commonly in children and young adults. Clinical presentation of the disease is characterized by fever, tonsillopharyngitis, lymphadenopathy, and hepatosplenomegaly, whereas serological findings of this benign disorder include positive heterophilic antibody formation (transient increase in heterophilic antibodies) and prominence of hematological lymphocytosis of more than 10% of atypical lymphocytes. An EBV infection is usually asymptomatic in childhood, but acute kidney injury can be a rare complication during its course. Most cases recover from the disease completely. Early recognition of EBV infection and estimation of its complication are important for its prognosis. In light of previous literature, we discuss the case evaluated as an EBV infection complicated by acute kidney injury in early childhood and results of tubulointerstitial nephritis shown on a renal biopsy that was later diagnosed as an EBV infection by serological examination.

scholarly journals Acute acalculous cholecystitis by Epstein-Barr virus infection: a rare association

2015 ◽  
Vol 7 (4) ◽  
Author(s):  
Liliana Branco ◽  
Maria Vieira ◽  
Cristiana Couto ◽  
Maria D. Coelho ◽  
Carla Laranjeira
Keyword(s):  
Epstein Barr Virus ◽  
Pediatric Population ◽  
Rare Complication ◽  
Acalculous Cholecystitis ◽  
Acute Acalculous Cholecystitis ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Ebv Infection ◽  
Epstein Barr ◽  
Barr Virus Infection

Acute acalculous cholecystitis (AAC) is a rare complication of Epstein Barr virus (EBV) infection, with only a few cases reported among pediatric population. This clinical condition is frequently associated with a favorable outcome and, usually, a surgical intervention is not required. We report a 16-year-old girl who presented with AAC following primary EBV infection. The diagnosis of AAC was documented by clinical and ultrasonographic examination, whereas EBV infection was confirmed serologically. A conservative treatment was performed, with a careful monitoring and serial ultrasonographic examinations, which led to the clinical improvement of the patient. Pediatricians should be aware of the possible association between EBV and AAC, in order to offer the patients an appropriate management strategy.

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