scholarly journals Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial   Commentary: Another piece of the Alzheimer's jigsaw

BMJ ◽  
1999 ◽  
Vol 318 (7184) ◽  
pp. 633-640 ◽  
Author(s):  
M. Rosler ◽  
R. Anand ◽  
A. Cicin-Sain ◽  
S. Gauthier ◽  
Y. Agid ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Efficacy And Safety ◽  
Randomised Controlled

scholarly journals How to appraise an article on therapy

1998 ◽  
Vol 22 (6) ◽  
pp. 342-344 ◽  
Author(s):  
James P. Warner ◽  
Robert Blizard
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Drug Therapy ◽  
Randomised Controlled Trial ◽  
Treatment Effect ◽  
Controlled Trial ◽  
Evidence Based ◽  
Medline Search ◽  
Published Evidence ◽  
Randomised Controlled

This first of a series of articles intended to guide clinicians through the evidence-based process assesses the published evidence for drug therapy in Alzheimer's disease. A Medline search identified a randomised, controlled trial of donepezil. Although this trial appeared to have a reasonably sound methodology, we had some doubts about the treatment effect and applicability of the results.

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