scholarly journals Covid-19: Young mother should be allowed to die in “almost unbearable” tragedy, says judge

BMJ ◽  
2021 ◽  
pp. n577
Author(s):  
Clare Dyer
Keyword(s):  

1994 ◽  
Vol 127 (6) ◽  
pp. 1985-1993 ◽  
Author(s):  
B K Kennedy ◽  
N R Austriaco ◽  
L Guarente

The yeast Saccharomyces cerevisiae typically divides asymmetrically to give a large mother cell and a smaller daughter cell. As mother cells become old, they enlarge and produce daughter cells that are larger than daughters derived from young mother cells. We found that occasional daughter cells were indistinguishable in size from their mothers, giving rise to a symmetric division. The frequency of symmetric divisions became greater as mother cells aged and reached a maximum occurrence of 30% in mothers undergoing their last cell division. Symmetric divisions occurred similarly in rad9 and ste12 mutants. Strikingly, daughters from old mothers, whether they arose from symmetric divisions or not, displayed reduced life spans relative to daughters from young mothers. Because daughters from old mothers were larger than daughters from young mothers, we investigated whether an increased size per se shortened life span and found that it did not. These findings are consistent with a model for aging that invokes a senescence substance which accumulates in old mother cells and is inherited by their daughters.



1963 ◽  
Vol 2 (2-3) ◽  
pp. 76-85 ◽  
Author(s):  
C.E. Blank ◽  
Mary Lord ◽  
M.D. Casey ◽  
B.M. Laurance


Cureus ◽  
2021 ◽  
Author(s):  
Deepak Rajput ◽  
Amit Gupta ◽  
Sweety Gupta ◽  
Ankit Rai ◽  
Sruthi Shasheendran






Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1334 ◽  
Author(s):  
Hyemin Min ◽  
Esther Youn ◽  
Yhong-Hee Shim

During pregnancy, most women are exposed to caffeine, which is a widely consumed psychoactive substance. However, the consequences of maternal caffeine intake on the child remain largely unknown. Here, we investigated the intergenerational effects of maternal caffeine intake on offspring in a Caenorhabditis elegans model. We treated a young mother (P0) with 10 mM of caffeine equivalent to 2–5 cans of commercial energy drinks and examined its reproduction and growth rate from P0 to F2 generation. The fertility decreased and embryonic lethality increased by defective oocytes and eggshell integrity in caffeine-ingested mothers, and F1 larval development severely retarded. These results were due to decreased production of vitellogenin protein (yolk) in caffeine-ingested mothers. Furthermore, effects of RNA interference of vitellogenin (vit) genes, vit-1 to vit-6, in P0 mothers can mimic those by caffeine-ingested mothers. In addition, RNA interference (RNAi) depletion of unc-62 (human Meis homeobox), a transcriptional activator for vit genes, also showed similar effects induced by caffeine intake. Taken together, maternal caffeine intake reduced yolk production mediated by the UNC-62 transcription factor, thereby disrupting oocyte and eggshell integrity and retarding larval development. Our study suggests the clinical significance of caffeine intake for prospective mothers.



2011 ◽  
Vol 4 (1) ◽  
pp. 59-80
Author(s):  
Christopher R. Latty ◽  
Kathleen Burns-Jager

This constructed narrative inquiry illustrates confluent stories of a young mother, Jenny, charged with child abuse and neglect; her foster care case worker, Rachel; and her therapist, Kathleen. As researchers, we discuss the positions of each person: mother, caseworker, therapist through storied fragments representing what is most important in how they came to understand the process of their year-long work together that led to Jenny's releasing her parental rights. Layering interviews and reflexive writings, we focus on decision-making and voice; about what it means to be a parent, a foster care worker, and a therapist in a community context where parent benefit from services and the child's best interest is a privileged societal discourse.



The Lancet ◽  
1985 ◽  
Vol 325 (8424) ◽  
pp. 342
Author(s):  
ChristineE. Cooper
Keyword(s):  


2010 ◽  
Vol 14 (1) ◽  
pp. 1-19 ◽  
Author(s):  
Molly Moloney ◽  
Geoffrey P. Hunt ◽  
Karen Joe-Laidler ◽  
Kathleen MacKenzie
Keyword(s):  


1993 ◽  
Vol 35 (2) ◽  
pp. 45-45
Author(s):  
ANTHONY HOWELL
Keyword(s):  


Sign in / Sign up

Export Citation Format

Share Document