scholarly journals Prevalence of hepatitis B virus infection and associated risk factors among pregnant women attending antenatal clinic in Mulago Hospital, Uganda: a cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. e033043
Author(s):  
Simon Peter Kayondo ◽  
Josaphat K Byamugisha ◽  
Peter Ntuyo

AimTo determine the prevalence and factors associated with hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital.DesignCross-sectional observational study.SettingMulago National Referral Hospital, Uganda, antenatal clinic.ParticipantsWe randomly selected 340 pregnant women attending their first antenatal visit at Mulago Hospital antenatal clinic.Primary outcomeHepatitis B surface antigen positivity.ResultsWe recruited 340 participants, with a mean age of 27±5.7 years, and a median gravidity of 3. The prevalence of hepatitis B virus infection among pregnant women attending the antenatal clinic in Mulago Hospital, in our study, was 2.9% (95% CI 1.58% to 5.40%, n=10). Factors positively associated with hepatitis B virus infection were: marital status (adjusted OR (aOR)=11.37, p=0.002), having a hepatitis B positive family member (aOR=49.52, p<0.001) and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient (aOR=61.69, p=0.015). Other factors such as age, socioeconomic status, number of sexual partners, HIV serostatus, piercing of ears and history of blood transfusion were not significantly associated with hepatitis B virus infection in this study.ConclusionThe prevalence of hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital was of intermediate endemicity. We found that marital status, having a hepatitis B positive family member at home and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient were independently associated with hepatitis B infection. Factors such as age, HIV status, history of blood transfusion, piercing of ears and social status were not associated with hepatitis B status in this study.

2019 ◽  
Author(s):  
Getnet Gedefaw ◽  
Fikadu Waltengus ◽  
Almaz Akililu ◽  
Kihinetu Gelaye

Abstract Objective This study aimed to determine the magnitude of serum HBsAg and the risk factors for Hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic random sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for Hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay.Results The overall prevalence of hepatitis B virus infection among pregnant women were 16(4.7%) (95% CI= 2.7, 7.7). Having a history of blood transfusion (AOR=5.2; 95% CI=1.2-22.3), having a history of multiple sexual partners (AOR=4.6; 95% CI=1.1-19.6) and having a history tonsillectomy (traditional surgical procedure) AOR=3.4; 95% CI=1.1-10.1) were the significant risk factors for Hepatitis B virus infection.


2019 ◽  
Author(s):  
Getnet Gedefaw ◽  
Fikadu Waltengus ◽  
Almaz Akililu ◽  
Kihinetu Gelaye

Abstract Objective: This study aimed to determine the magnitude of serum HBsAg and the risk factors for Hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for Hepatitis B surface antigen (HBsAg) using Enzyme Linked Immuno Sorbent Assay. Results: The overall magnitude of hepatitis B virus infection among pregnant women were 16(4.7%) (95% CI= 2.7, 7.7).Having a history of blood transfusion (AOR=5.2; 95% CI=1.2-22.3), having a history of multiple sexual partners (AOR=4.6; 95% CI=1.1-19.6) and having a history traditional tonsillectomy (AOR=3.4; 95% CI=1.1-10.1) were the major predictor factors for Hepatitis B virus infection. Keywords: Pregnant women, Bahirdar, Ethiopia, Hepatitis B virus


2019 ◽  
Author(s):  
Getnet Gedefaw ◽  
Fikadu Waltengus ◽  
Almaz Akililu ◽  
Kihinetu Gelaye

Abstract Objective This study aimed to determine the magnitude of serum HBsAg and the risk factors for Hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic random sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for Hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay.Results The overall prevalence of hepatitis B virus infection among pregnant women were 16(4.7%) (95% CI= 2.7, 7.7). Having a history of blood transfusion (AOR=5.2; 95% CI=1.2-22.3), having a history of multiple sexual partners (AOR=4.6; 95% CI=1.1-19.6) and having a history tonsillectomy (traditional surgical procedure) AOR=3.4; 95% CI=1.1-10.1) were the significant risk factors for Hepatitis B virus infection.


2016 ◽  
Vol 76 ◽  
pp. 66-71 ◽  
Author(s):  
Rania A. Tohme ◽  
Jocelyne Andre-Alboth ◽  
Alexandra Tejada-Strop ◽  
Ran Shi ◽  
Jacques Boncy ◽  
...  

2014 ◽  
Vol 40 (2) ◽  
pp. 50-53 ◽  
Author(s):  
R Yasmin ◽  
SA Ahmed ◽  
F Zaman ◽  
M Ansari ◽  
E Azim

This cross sectional study was carried out among 146 garment workers from selected two garments industries to find out the magnitude of Hepatitis B virus infection in Narayangonj. Data was collected through face to face interview of the workers by using a pre tested questionnaire. The study was conducted during April to June 2007.Majority 56.2% were in the age group of 18-25 years followed by 32.9% were of 26-35 years. By sex partner majority 28.8% had their partnership with their husband, 11% had partnership with their wife and 2. 7% had sexual relation with their boyfriend and 5.5% had relation with their girlfriend, 8. 9% had history of sex with commercial sex worker. In this study only 11 (7.5%) respondents had HBV positive. Among them who had the history of inject able drug taking 8(2.05%) were found positive. Statistically it was found highly significant. History of jaundice, only 1 (0.7%) respondents had HBV positive while those who had no history of jaundice 10 (6.8%) had HBV positive. In this study it was found that 6(46.2%) HBV positive respondents who had sex with commercial sex worker and none of the respondents those who had sex with their wife were HBV negative. This was found statistically significant, that means development of hepatitis B virus might has an association of sex with sex worker. The study recommended mass screening of hepatitis should be conducted among the garments workers as it was found highly prevalence among the study workers. DOI: http://dx.doi.org/10.3329/bmj.v40i2.18511 Bangladesh Medical Journal 2011 Vol.40(2): 50-53


2021 ◽  
Vol 12 ◽  
pp. 215013272199362
Author(s):  
Mhiret Belay Tadiwos ◽  
Girum Gebremeskel Kanno ◽  
Abriham Shiferaw Areba ◽  
Robel Hussen Kabthymer ◽  
Zeleke Girma Abate ◽  
...  

Background: Hepatitis B virus infection is a major public health problem worldwide and is a major cause of morbidity and mortality. This study aimed to assess the prevalence of hepatitis B virus infection and associated factors among pregnant mothers in the Gedeo Zone, southern Ethiopia. Methods: An institution-based cross-sectional study was conducted among 479 pregnant women visiting governmental and private health facilities in the Gedeo zone from January to April 2019. We selected study participants using systematic random sampling techniques. The Eugene strip test was used to determine hepatitis B virus infection among pregnant mothers. We collected the status of HIV of the pregnant women from the records. Other variables were collected from the mothers using interviewer-administered questionnaires. We used binary and multivariable logistic regression for the analysis. An adjusted odds ratios and their 95% confidence intervals (CIs) were calculated to determine the association between HBsAg sero-positivity and various factors. A P-value of less than .05 was considered significant. Results: This study revealed that the prevalence of hepatitis B virus infection among pregnant mothers was 9.2% in Gedeo Zone. A previous history of blood transfusion [AOR = 5.2, 95% CI: 2.1, 12.5], a previous history of hospital admission [AOR = 3, 95% CI: 1.4, 6.6], a history of having an abortion [AOR = 4.1, 95 % CI: 1.5, 11.7], the age of the pregnant women [AOR = 5.1, 95 % CI: 1.5, 18.0], and their HIV status [AOR = 8.1, 95 % CI: 1.9, 36.0] had a statistically significant association with HBsAg sero-positivity. Conclusion: Hepatitis B virus infection was found to have higher endemicity (9.2%) in Gedeo Zone which is higher than the national pooled prevalence which was 4.75%. The health facilities must implement early initiation of antenatal care services which incorporate the prevention and control of HBV in the Gedeo Zone.


Sign in / Sign up

Export Citation Format

Share Document