scholarly journals Re-evaluation of the left atrial to aortic root ratio as a marker of patent ductus arteriosus.

1994 ◽  
Vol 70 (2) ◽  
pp. F112-F117 ◽  
Author(s):  
P Iyer ◽  
N Evans
Keyword(s):  
Patent Ductus Arteriosus ◽  
Aortic Root ◽  
Left Atrial ◽  
Ductus Arteriosus ◽  
Patent Ductus

scholarly journals Role of Sequential Functional Echocardiography in Predicting Clinically Apparent Patent Ductus Arteriosus in Preterm Very Low Birth Weight Newborns-An Observational Study

2020 ◽  
Author(s):  
Anchala Bhardwaj ◽  
ARVIND SAILI ◽  
Dinesh Kumar Yadav ◽  
Ajay Kumar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Patent Ductus Arteriosus ◽  
Left Atrial ◽  
Very Low Birth Weight ◽  
Ductus Arteriosus ◽  
Preterm Neonates ◽  
Predictive Utility ◽  
Patent Ductus

Abstract Background The management of patent ductus arteriosus in preterm neonates continues to be a topic of discussion and controversy. Prolonged ductal patency in preterm neonates has been associated with significant short and long term morbidities and with increased mortality however, policy of routine treatment of all during neonatal period has failed to show significant improvement in long term outcome. Echocardiography has emerged as a promising modality to screen the newborns at risk of adverse effects of ductal shunting. This helps in identifying PDAs that require treatment to ultimately prevent unnecessary therapy or delay of necessary therapy. There are multitude of studies that have evaluated large number of echocardiographic markers for their predictive utility but only few have included all ductal markers together in a single study. The reported sensitivity (26-100%) and specificity (6-100%) of echocardiographic markers vary over a wide range. Thus, this study was planned with an aim to assess the predictive utility of all available ductal markers and their added advantage of having all over few ones in clinically apparent PDA in preterm VLBW newborns.Methods It was an observational prospective study conducted in tertiary care NICU at Lady Hardinge Medical College, Delhi. Fifty preterm very low birth weight (VLBW) newborns underwent four sequential Echo scans within first 72 hrs; first scan within 12 hours then at 24 hrs ,48 hrs and 72 hrs of age and were monitored clinically for the signs of PDA up to two weeks of life or discharge whichever comes later.Results The Ductal diameter, pulsatile ductal flow pattern, Left pulmonary artery (LPA) velocity, Left atrial to aortic width (La/Ao) ratio, Left atrial volume index (LAVI), Left ventricle to aortic width (Lv/Ao) ratio, E/A ratio and Left ventricular output/superior vena caval (LVO/SVC) flow ratio predicted clinically apparent PDA during first 72 hours of life.Conclusion This study provides insights into the predictive utility of other ductal echo markers along with the routinely measured conventional ones during first 72 hours of life in preterm VLBW newborns.

Echocardiographic Characteristics of Premature Infants with Patent Ductus Arteriosus

PEDIATRICS ◽  
1983 ◽  
Vol 72 (6) ◽  
pp. 864-871 ◽  
Author(s):  
Gregory L. Johnson ◽  
Gerard L. Breart ◽  
Michael H. Gewitz ◽  
Joel I. Brenner ◽  
Peter Lang ◽  
...  
Keyword(s):  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Aortic Root ◽  
Ductus Arteriosus ◽  
Left Ventricular ◽  
Time Interval ◽  
Systolic Time Interval ◽  
Systolic Time ◽  
Interval Ratio ◽  
Patent Ductus

As part of a multicenter collaborative study, M-mode echocardiograms were obtained shortly after birth on 3,559 premature infants with birth weight ≤1,750 g. Of these infants, 1,496 did not develop a cardiac murmur or other signs of a "hemodynamically significant" patent ductus arteriosus (PDA). Echocardiographic parameters from this "normal" group were compared with results obtained from 415 infants in whom PDA was diagnosed on the basis of clinical findings alone, irrespective of the echocardiogram (PDA group). The best discrimination between the two groups, when considering a single parameter, was provided by a left atrial to aortic root ratio (LA/AO) of 1.40, a left ventricular to aortic root ratio (LV/AO) of 2.10, or a left ventricular systolic time interval ratio (LPEP/LVET) of 0.27. Multivariate analysis demonstrated that better separation between the two groups occurred when the left atrial to aortic root ratio and the left ventricular systolic time interval ratio were considered jointly. Because of a large degree of overlap of all echocardiographic variables between the normal group and the group with PDA, the echocardiogram alone was not a good indicator of PDA. However, when used in conjunction with a priori estimates of the probability of PDA (based, for example, on birth weight and degree of respiratory disease), use of echocardiographic data was found to improve the detection of hemodynamically significant patent ductus arteriosus in premature infants.

Patent Ductus Arteriosus Before and After Surgery

1989 ◽  
Vol 29 (3-4) ◽  
pp. 39-51
Author(s):  
Bambang Madiyono ◽  
Ismet N. Oesman ◽  
Sudigdo Sastroasmoro ◽  
Sukman Tulus Putra ◽  
Eva Jeumpa Soelaiman ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Patent Ductus Arteriosus ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Ductus Arteriosus ◽  
Left Ventricular ◽  
Systolic Murmur ◽  
Surgical Closure ◽  
Pulmonary Flow ◽  
Patent Ductus

Twenty five patients with patent ductus arteriosus, who had undergone surgical closure were studied retrospectively. Girls were more affected than boys; the sex ratio was 4 : I. Associated cardiac lesions were diagnosed in 3 patients, two with ventricular septal defect and one with congenital mitral stenosis. Congestive heart failure was diagnosed in 5 patients before surgery. Typical continuous murmur was heard in most cases (76%), while in the rest only systolic murmur was detected. Electrocardiographic left atrial enlargement, left ventricular hypertrophy and right ventricular hypertrophy were found in 8%, 48% and 40%, respectively.Cardiomegaly with increased pulmonary vascular markings was found in 60% of cases, while ratio of left atrial to aortic root diameter greater than 1.2 was detected in 60% of patients. The PDA could be directly visualized by echocardiography in 15 cases.Cardiac catheterization was performed in 17 cases, 47% with hyperkinetic pulmonary hypertension, 41% with high pulmonary flow without pulmonary hypertension and 12% with mild increased pulmonary flow. The pulmonary-systemic flow ratio (Qp/Qs) was more correlated to pulmonary vascular markings rather than to cardio-thoracic ratio. Division of the ductus was the procedure of choice, but in 16% of cases ductal ligation was performed because of technical reasons. Postoperative catch-up in both weight and height was observed more clearly in  children operated at earlier age. Ejection systolic murmur was still detected in 2 patients, in whom hyperkinetic pulmonary hypertension existed prior to surgery. No cardiomegaly was found in patients followedup I year or more after surgery. The mortality was nil.

Retrospective evaluation of occlusion of patent ductus arteriosus with hemoclips in 20 dogs

2000 ◽  
Vol 36 (6) ◽  
pp. 548-555 ◽  
Author(s):  
LB Corti ◽  
D Merkley ◽  
OL Nelson ◽  
WA Ware
Keyword(s):  
Clinical Outcome ◽  
Patent Ductus Arteriosus ◽  
Left Atrial ◽  
Ductus Arteriosus ◽  
Retrospective Evaluation ◽  
Good Clinical Outcome ◽  
Heart Size ◽  
Fractional Shortening ◽  
Patent Ductus

Twenty dogs with patent ductus arteriosus occluded with Hemoclips were evaluated with a mean follow-up time of 799.4 days (range, 83 to 3,580 days). Significant decreases were found between pre- and postsurgical means for vertebral heart size and for echocardiographic left atrial/aortic-root ratios and percent fractional shortening (%FS). Despite a good clinical outcome, six of 20 dogs had persistent cardiomyopathy of overload with diminished %FS (28% or less) at follow-up. One dog had residual ductal flow identified five days postoperatively. Subsequent evaluations in this case at 60, 144, 226, 344, and 560 days postoperatively demonstrated gradually diminishing ductal flow. The remaining 19 dogs did not recanalize.

Device Closure of Patent Ductus Arteriosus in Marfan Patients: Safety and Effect on the Aortic Root Diameter

2010 ◽  
Vol 5 (5) ◽  
pp. 439-443 ◽  
Author(s):  
Keyhan S. Zanjani ◽  
Abdul Rahim Wong ◽  
Masood Sadiq ◽  
Howard S. Weber ◽  
Nancy G. Cutler
Keyword(s):  
Patent Ductus Arteriosus ◽  
Aortic Root ◽  
Ductus Arteriosus ◽  
Root Diameter ◽  
Device Closure ◽  
Patent Ductus

scholarly journals Patent ductus arteriosus and pulmonary artery aneurism in a child affected by Loeys-Dietz syndrome

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Marcello Marcì
Keyword(s):  
Pulmonary Artery ◽  
Patent Ductus Arteriosus ◽  
Cleft Palate ◽  
Current Literature ◽  
Aortic Root ◽  
Ductus Arteriosus ◽  
Rare Association ◽  
Patent Ductus

We report the case of a 3-year old girl affected by Loeys-Dietz syndrome, a rare association of aneurysms and tortuosity of arteries associated to hypertelorism and cleft palate that was firstly described by Loeys and Dietz in 2005. The patient developed aneurysms of aortic root and of pulmonary artery, besides a patent ductus arteriosus was evidenced. We also reviewed the current literature concerning the aetiology and management of this syndrome.

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