scholarly journals PTH-194 A Retrospective Analysis of Glucose-Hydrogen Breath test for Small Intestine Bacterial Overgrowth in a Teaching Hospital

Gut ◽  
2013 ◽  
Vol 62 (Suppl 1) ◽  
pp. A290.2-A291
Author(s):  
S West ◽  
A C Ford ◽  
K Argyle ◽  
D Hick ◽  
J S Jennings
Keyword(s):  
Small Intestine ◽  
Retrospective Analysis ◽  
Teaching Hospital ◽  
Breath Test ◽  
Bacterial Overgrowth ◽  
Hydrogen Breath Test ◽  
Small Intestine Bacterial Overgrowth

Treatment of Small Intestine Bacterial Overgrowth with Rifaximin, a Non-Absorbable Rifamycin

1988 ◽  
Vol 16 (4) ◽  
pp. 312-316 ◽  
Author(s):  
G. R. Corazza ◽  
M. Ventrucci ◽  
A. Strocchi ◽  
M. Sorge ◽  
L. Pranzo ◽  
...  
Keyword(s):  
Small Intestine ◽  
Side Effects ◽  
Small Bowel ◽  
Therapeutic Efficacy ◽  
Breath Test ◽  
Bacterial Overgrowth ◽  
Hydrogen Breath Test ◽  
Small Bowel Bacterial Overgrowth ◽  
Small Intestine Bacterial Overgrowth ◽  
Lactulose Hydrogen Breath Test

In twelve patients affected by small bowel bacterial overgrowth, diagnosed by means of the lactulose hydrogen breath test, the therapeutic efficacy of a non-absorbable derivative of rifamycin, rifaximin, was evaluated. This study showed that this drug has a satisfactory therapeutic efficacy in contaminated small bowel syndrome and, at the doses tested, is free of side-effects.

scholarly journals Small intestine bacterial overgrowth is frequent in cystic fibrosis: combined hydrogen and methane measurements are required for its detection.

1970 ◽  
Vol 56 (4) ◽  
Author(s):  
Aleksandra Lisowska ◽  
Jerzy Wójtowicz ◽  
Jarosław Walkowiak
Keyword(s):  
Cystic Fibrosis ◽  
Small Intestine ◽  
Breath Test ◽  
Gastrointestinal Symptoms ◽  
Bacterial Overgrowth ◽  
Additional Measurement ◽  
Hydrogen Breath Test ◽  
Small Intestine Bacterial Overgrowth ◽  
Comparative Group ◽  
Methane Measurement

Hydrogen breath test (BT) is commonly used as a diagnostic tool for the detection of small intestine bacterial overgrowth (SIBO). It was reported that colonic methane production is far more frequent in cystic fibrosis (CF) patients than in other subjects. Therefore, measuring exclusively hydrogen in the diagnostic breath test for diagnosing SIBO might be of limited value. We aimed to assess the usefulness of combined measurement of hydrogen and methane expiration for the diagnosis of SIBO in CF. The study comprised 62 CF patients aged 5 to 18 years. Three-hundred-ninety subjects assessed due to gastrointestinal symptoms for the presence of SIBO served as a comparative group. In all subjects hydrogen/methane BT using glucose was performed. A positive BT was defined as fasting hydrogen > or = 20 ppm or fasting methane > or = 10 ppm or a rise of > or = 12 ppm hydrogen or > or = 6 ppm methane over baseline during the test. In 23 (37.1%) CF patients and in 52 (13.3%) subjects from the comparative group abnormal BT results were found. In seven (11.3%) CF patients and 29 (7.4%) of the other subjects studied methane measurement allowed diagnosis of SIBO. Small intestine bacterial overgrowth is frequent in cystic fibrosis. For its detection in cystic fibrosis and other gastrointestinal patients, combined hydrogen and methane measurement instead of hydrogen breath test should be applied. Without the additional measurement of methane a significant percentage of SIBO will be missed.

Glucose-H2 breath test for small intestine bacterial overgrowth

1990 ◽  
Vol 98 (1) ◽  
pp. 253-254 ◽  
Author(s):  
Ginoroberto Corazza ◽  
Margherita Sorge ◽  
Alessandra Strocchi ◽  
Giovanni Gasbarrini
Keyword(s):  
Small Intestine ◽  
Breath Test ◽  
Bacterial Overgrowth ◽  
Small Intestine Bacterial Overgrowth ◽  
H2 Breath Test

scholarly journals Detection of Small Intestine Bacterial Overgrowth by Means of a 14C-D-Xylose Breath Test

1979 ◽  
Vol 77 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Charles E. King ◽  
Phillip P. Toskes ◽  
John C. Spivey ◽  
Erhard Lorenz ◽  
Susan Welkos
Keyword(s):  
Small Intestine ◽  
Breath Test ◽  
Bacterial Overgrowth ◽  
Small Intestine Bacterial Overgrowth

scholarly journals PREVALENCE OF SMALL INTESTINE BACTERIAL OVERGROWTH IN PATIENTS WITH GASTROINTESTINAL SYMPTOMS

2017 ◽  
Vol 54 (2) ◽  
pp. 91-95 ◽  
Author(s):  
Carolina Piedade MARTINS ◽  
Caio Henrique Amorim CHAVES ◽  
Maurício Gustavo Bravim de CASTRO ◽  
Isabel Cristina GOMES ◽  
Maria do Carmo Friche PASSOS
Keyword(s):  
Small Intestine ◽  
Breath Test ◽  
Gastrointestinal Symptoms ◽  
Bacterial Overgrowth ◽  
Bacterial Metabolism ◽  
Breath Tests ◽  
Small Intestine Bacterial Overgrowth ◽  
Exhaled Air ◽  
Gastrointestinal Complaints ◽  
Number Of Individuals

ABSTRACT BACKGROUND Small intestine bacterial overgrowth is a heterogeneous syndrome characterized by an increase in the number and/or the presence of atypical microbiota in the small intestine. The symptoms of small intestine bacterial overgrowth are unspecific, encompassing abdominal pain/distension, diarrhea and flatulence. Due to the increased cost and complexity for carrying out the jejunal aspirate, the gold standard for diagnosis of the syndrome, routinely the hydrogen (H 2 ) breath test has been used, utilizing glucose or lactulose as substrate, which is able to determine, in the exhaled air, the H 2 concentration produced from the intestinal bacterial metabolism. However, due to a number of individuals presenting a methanogenic microbiota, which does not produce H 2 , the testing on devices capable of detecting, concurrently, the concentration of exhaled H 2 and methane (CH 4 ) is justified. OBJECTIVE This study aimed to determine the prevalence of small intestine bacterial overgrowth in patients with digestive symptoms, through a comparative analysis of breath tests of H 2 or H 2 and CH 4 associated, using glucose as substrate . METHODS A total of 200 patients of both sexes without age limitation were evaluated, being directed to a Breath Test Laboratory for performing the H 2 test (100 patients) and of exhaled H 2 and CH 4 (100 patients) due to gastrointestinal complaints, most of them patients with gastrointestinal functional disorders. RESULTS The results indicated a significant prevalence of small intestine bacterial overgrowth in the H 2 test and in the test of exhaled H 2 and CH 4 (56% and 64% respectively) in patients with gastrointestinal symptoms, and higher prevalence in females. It found further that methane gas was alone responsible for positivity in 18% of patients. CONCLUSION The data found in this study is consistent with the findings of the current literature and underscores the need for using devices capable of capturing the two gases (exhaled H 2 and CH 4 ) to improve the sensitivity and hence the accuracy of small intestine bacterial overgrowth diagnosis in daily medical practice.

Comparison of the one-gramd-[14C]xylose breath test to the [14C]bile acid breath test in patients with small-intestine bacterial overgrowth

1980 ◽  
Vol 25 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Charles E. King ◽  
Phillip P. Toskes ◽  
Tomas R. Guilarte ◽  
Erhard Lorenz ◽  
Susan L. Welkos
Keyword(s):  
Small Intestine ◽  
Bile Acid ◽  
Breath Test ◽  
Bacterial Overgrowth ◽  
Small Intestine Bacterial Overgrowth ◽  
The One

scholarly journals ASSOCIATION OF NONALCOHOLIC FATTY LIVER DISEASE WITH SMALL INTESTINE BACTERIAL OVERGROWTH IN OBESE CHILDREN

2019 ◽  
Vol 72 (3) ◽  
pp. 350-356
Author(s):  
Yuriy M. Stepanov ◽  
Natalia Yu. Zavhorodnia ◽  
Victoria B. Yagmur ◽  
Olga Yu. Lukianenko ◽  
Elvira V. Zygalo
Keyword(s):  
Risk Factors ◽  
Small Intestine ◽  
Glucose Level ◽  
Liver Steatosis ◽  
Bacterial Overgrowth ◽  
Test Method ◽  
Homa Index ◽  
Obese Children ◽  
Hydrogen Breath Test ◽  
Small Intestine Bacterial Overgrowth

Introduction: In recent years, NAFLD is considered as the key of the so-called metabolic inflammation, in which the intestinal microbiota plays an important role. The aim: To determine the effect of small intestine bacterial overgrowth on the liver structural and functional parameters in children with obesity and overweight. Materials and methods: The object of the study was 89 children with obesity/overweight. Depending on the presence of SIBO based on the results of the hydrogen breath test with glucose, the patients were divided into 2 groups: first (I) consisted of 31 children with SIBO, the second (II) included 58 children without SIBO. All the patients under study performed a general blood analysis and a biochemical blood test, immuno-enzyme test method with insulin level determination HOMA index calculation. For diagnostics of the liver steatosis, transient elastography with the CAP (controlled attenuation parameter) function was carried out using FibroScan® 502 touch (Echosens, Paris, France). Results: According to fibroscan data, the presence of SIBO in obese children can lead to raise of CAP level; liver steatosis was diagnosed in 22 patients (70.9%) of the 1st group and 24 patients (41.4%) of the 2 group (p<0,05). We found significant differences in the the ratio of neutrophils and lymphocytes (NLR) (p <0.05). The average glucose level and HOMA index were significantly higher in SIBO group (p<0,05). The analysis of risk factors of SIBO showed that metabolic syndrome and NAFLD as the risk factors for SIBO development (p<0,05). Conclusions: SIBO has an effect on the structural and functional characteristics of the liver resulting in higher insulin and glucose level, higher NLR level and greater prevalence of NAFLD.

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