scholarly journals IDDF2020-ABS-0079 A single centre retrospective study of inpatient management in acute lower gastrointestinal bleeding

Author(s):  
Wilson Siu ◽  
Yusuke Onishi ◽  
Wamedh Taj-Aldeen ◽  
Balasubramaniam Vijayan
2021 ◽  
Author(s):  
Hyun Suk Lee ◽  
Hee Seok Moon ◽  
In Sun Kwon ◽  
Hyun Yong Jeong ◽  
Byung Seok Lee ◽  
...  

Abstract Background Lower gastrointestinal bleeding (LGIB) often subsides by itself; however, in some cases, the bleeding does not stop and the patient’s condition worsens. Therefore, if the occurrence of severe lower gastrointestinal bleeding can be predicted in advance, it can be helpful for treatment. This study aimed to evaluate variables related to mortality from LGIB and to propose a scoring system. Methods This retrospective study reviewed the medical records of patients who visited the emergency room with hematochezia between January 2016 and December 2020. Through regression analysis of vital signs, laboratory investigations, and hospital stay, variables related to LGIB-related mortality were evaluated. A scoring system was developed, and the appropriateness with an area under the receiver operating characteristics curve (AUROC) was evaluated and compared with other existing models. Results A total of 932 patients were hospitalized for LGIB. Variables associated with LGIB-related mortality were the presence of cancer, heart rate of > 100 beats/min, blood urea nitrogen level of ≥ 30 mg/dL, an international normalized ratio of > 1.50, and albumin level of ≤ 3.0 g/dL. The AUROCs of CNUH-4 and CNUH-5 were 0.890 (p < 0.001; cutoff, 2.5; 95% confidence interval, 0.0851 − 0.929) and 0.901 (p < 0.001; cutoff, 3.5; 95% confidence interval, 0.869 − 0.933), respectively. Conclusions The model developed for predicting the risk of LGIB-related mortality is simple and easy to apply clinically. The AUROC of the model was better than that of the existing models.


2021 ◽  
Vol 09 (12) ◽  
pp. E1869-E1869
Author(s):  
Paola Soriani ◽  
Paola Biancheri ◽  
Cesare Hassan ◽  
Mauro Manno

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Yuan Zhao ◽  
Gang Li ◽  
Xiang Yu ◽  
Ping Xie

Background. To investigate the safety and efficacy of superselective transcatheter arterial embolization (TAE) with n-butyl cyanoacrylate (NBCA) in treating lower gastrointestinal bleeding caused by angiodysplasia.Methods. A retrospective study was performed to evaluate the clinical data of the patients with lower gastrointestinal bleeding caused by angiodysplasia. The patients were treated with superselective TAE with NBCA between September 2013 and March 2015. Angiography was performed after the embolization. The clinical signs including melena, anemia, and blood transfusion treatment were evaluated. The complications including abdominal pain and intestinal ischemia necrosis were recorded. The patients were followed up to evaluate the efficacy in the long run.Results. Seven cases (2 males, 5 females; age of69.55±2.25) were evaluated in the study. The embolization was successfully performed in all cases. About 0.2–0.8 mL (mean0.48±0.19 mL) NCBA was used. Immediate angiography after the embolization operation showed that the abnormal symptoms disappeared. The patients were followed up for a range of 2–19 months and six patients did not reoccur. No serious complications, such as femoral artery puncture point anomaly, vascular injury, and intestinal necrosis perforation were observed.Conclusion. For the patients with refractory and repeated lower gastrointestinal hemorrhage due to angiodysplasia, superselective TAE with NBCA seem to be a safe and effective alternative therapy when endoscopy examination and treatment do not work.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hyun Seok Lee ◽  
Hee Seok Moon ◽  
In Sun Kwon ◽  
Hyun Yong Jeong ◽  
Byung Seok Lee ◽  
...  

Abstract Background Lower gastrointestinal bleeding (LGIB) often subsides without medical intervention; however, in some cases, the bleeding does not stop and the patient’s condition worsens. Therefore, predicting severe LGIB in advance can aid treatment. This study aimed to evaluate variables related to mortality from LGIB and propose a scoring system. Methods In this retrospective study, we reviewed the medical records of patients who visited the emergency room with hematochezia between January 2016 and December 2020. Through regression analysis of comorbidities, medications, vital signs, laboratory investigations, and duration of hospital stay, variables related to LGIB-related mortality were evaluated. A scoring system was developed and the appropriateness with an area under the receiver operating characteristics curve (AUROC) was evaluated and compared with other existing models. Results A total of 932 patients were hospitalized for LGIB. Variables associated with LGIB-related mortality were the presence of cancer, heart rate > 100 beats/min, blood urea nitrogen level ≥ 30 mg/dL, an international normalized ratio > 1.50, and albumin level ≤ 3.0 g/dL. The AUROCs of the models CNUH-4 and CNUH-5 were 0.890 (p < 0.001; cutoff, 2.5; 95% confidence interval, 0.0851–0.929) and 0.901 (p < 0.001; cutoff, 3.5; 95% confidence interval, 0.869–0.933), respectively. Conclusions The model developed for predicting the risk of LGIB-related mortality is simple and easy to apply clinically. The AUROC of the model was better than that of the existing models.


2021 ◽  
Vol 33 (2) ◽  
pp. 120-122
Author(s):  
Madhusudan Saha ◽  
Md Anisur Rahman ◽  
Mohammad Zakaria ◽  
Musammat Aklima Akter Hely ◽  
Nasrin Aktar ◽  
...  

Introduction: This retrospective study was done to see colonoscopic yields in patients presenting with lower gastrointestinal bleeding. Materials & Methods: Reports of patients undergoing colonoscopy due to bleeding per rectum were retrieved from endoscopy records. Patients’ particulars and colonoscopic findings were recorded in a data sheet. Analysis was done using SPSS 20 version. Results: A total of 309 patients (male 211 (68.3%) and female 98 (31.7) with mean age 40.3 years %)) were included in this study. According to colonoscopic yield, causes of LGIB were haemorrhoids 137 (44.33% ), rectal and colonic growth 58(18.77% ) rectal and colonic polyps 54 (17.47% ), anal fissure 38 (12.29% ), proctitis 18 (5.82%), colitis 18(5.82%), ileal ulcer and ileitis 34(11.0%). Colorectal growth was more common among patients age 26 to 60years. Among male rectal growth was slightly higher than female. Conclusion: Lower gastrointestinal bleeding is more common among males. Commonest cause of LGIB are internal haemorrhoids, rectal growth, rectal and colonic polyps and anal fissure. Colorectal neoplasm, proctitis, colitis and ileal inflammation and ulcers constitute small part. Medicine Today 2021 Vol.33(2): 120-122


2017 ◽  
Vol 54 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Pedro BOAL CARVALHO ◽  
Joana MAGALHÃES ◽  
Francisca DIAS DE CASTRO ◽  
Sara MONTEIRO ◽  
Bruno ROSA ◽  
...  

ABSTRACT BACKGROUND Small bowel bleeding is a leading indication for small bowel capsule endoscopy. The Suspected Blood Indicator (SBI) is a software feature directed to automatically detect bleeding lesions during small bowel capsule endoscopy. OBJECTIVE We aimed to assess SBI diagnostic accuracy for small bowel haemorrhage or potentially bleeding lesions during small bowel capsule endoscopy for small bowel bleeding. Methods - Single-centre retrospective study including 281 consecutive small bowel capsule endoscopy performed for small bowel bleeding during 6 years. The investigators marked lesions with high bleeding potential (P2), such as angioectasias, ulcers and tumours, as well as active bleeding during regular small bowel capsule endoscopy viewing with PillCam SB2(r). All small bowel capsule endoscopy were independently reviewed by another central reader using SBI. RESULTS Among the 281 patients, 29 (10.3%) presented with active haemorrhage while 81 (28.9%) presented with a P2 lesion. The most frequently observed P2 lesions were angioectasias (52), ulcers (15), polyps (7) and ulcerated neoplasias (7). SBI showed a 96.6% (28/29) sensitivity for active small bowel bleeding, with a 97.7% negative predictive value. Regarding P2 lesions, the SBI displayed an overall sensitivity of 39.5%, being highest for ulcerated neoplasias (100%), but significantly lower for angioectasias (38.5%) or ulcers (20.0%). CONCLUSION Although SBI sensitivity for the automatic detection of potentially bleeding lesions was low, it effectively detected active small bowel bleeding with very high sensitivity and negative predictive value.


Sign in / Sign up

Export Citation Format

Share Document