GW24-e0353 A novel mutation R397Q in KCNQ1 gene caused dilated cardiomyopathy with ventricular tachycardia and prolonged QT interval

Heart ◽  
2013 ◽  
Vol 99 (Suppl 3) ◽  
pp. A1.1-A1 ◽  
Author(s):  
Xiong Qinmei ◽  
Zhou Qiongqiong ◽  
Zhou Hui ◽  
Liu Xiuxia ◽  
Cao Qing ◽  
...  
2019 ◽  
Vol 77 (5) ◽  
pp. 584-585
Author(s):  
Małgorzata Peregud‑Pogorzelska ◽  
Jarosław Kaźmierczak ◽  
Małgorzata Zielska ◽  
Jakub Pobłocki ◽  
Mieczysław Walczak ◽  
...  

1994 ◽  
Vol 127 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Ameeta B Martin ◽  
Arthur Garson ◽  
James C Perry

1996 ◽  
Vol 11 (S2) ◽  
pp. S40-S40
Author(s):  
William Brady ◽  
Daniel DeBehnke ◽  
Dennis Laundrie ◽  
Jeffrey A. Skiles

Objective: To determine the prevalence and outcome of out-of-hospital ventricular tachycardia (VT) cardiac arrest with a prolonged QT interval and to identify the subset with torsades de pointes (TdP).Methods: Design: Retrospective review. Setting: Fire department-based paramedic system. Participants: Non-traumatic VT cardiac arrest (1/91-12/94) with a supraventricular perfusing rhythm (SVPR) and a measurable QT interval. Interventions: QT interval was measured from a SVPR and corrected QT interval (QTc) was calculated (prolonged if ≥0.45 sec). VT was classified as polymorphic or monomorphic.Results: 190 patients met inclusion criteria. 51% of patients had a prolonged QTc (PQTc). The overall hospital discharge rate was 28.4%. No difference with respect to paramedic-witnessed arrests in each QTc group was found (25.8% normal QTc [NQTc] vs. 27.8% PQTc; p = 0.752). Patients with PQTc were less likely to be discharged from the hospital (19.6% vs. 37.6%; p = 0.01). Patients with PQTc were not more likely to have PVT (37% vs. 40%; p = 0.705). 16 (8.4%) patients had TdP. 27.8% of TdP and 26.8% of non-TdP patients were discharged (p = 0.912).


2017 ◽  
Vol 35 (5) ◽  
pp. 804.e5-804.e6 ◽  
Author(s):  
Max Wentlandt ◽  
Stephen C. Morris ◽  
Steven H. Mitchell

1990 ◽  
Vol 10 (1) ◽  
pp. 66-72
Author(s):  
Makoto TOHYAMA ◽  
Hideyoshi FUJIHARA ◽  
Ryo KIMURA ◽  
Kazunori SATO

2016 ◽  
Author(s):  
Gary Green ◽  
Sally Graglia

Wide-complex tachycardias (WCTs) should always alert the emergency physician to a potentially immediate or rapidly developing, life-threatening scenario. The approach to these patients should follow general emergency medicine principles. The review covers the pathophysiology, stabilization and assessment, diagnosis and treatment, and disposition and outcomes of WCT. Figures show a basic electrocardiogram (ECG) tracing, an ambulatory monitoring strip of a patient with recurrent presyncope showing repetitive monomorphic ventricular tachycardia, a 12-lead ECG of a rapid wide QRS tachycardia due to an antidromic atrioventricular reciprocating tachycardia in a patient with Wolff-Parkinson-White (WPW) syndrome, an example of pacemaker-mediated tachycardia, ventricular tachycardia occurring in the context of QT prolongation consistent with torsades de pointes, a 12-lead ECG in a patient with WPW syndrome showing a rapid, irregular ventricular rate and wide QRS complexes of atrial fibrillation with a short refractory period, an ECG representative of tricyclic antidepressant overdose, and an algorithm for identifying patients with systolic heart failure and left ventricular ejection fraction less than or equal to 35% who are candidates for an implantable cardioverter-defibrillator. Tables list causes of regular WCT, causes of prolonged QT interval, common medications with potential QT prolongation activity, pharmacologic treatment options for stable patients with WCT, Kindwall and colleagues’ criteria for ventricular tachycardia, Brugada and colleagues’ criteria for ventricular tachycardia, Vereckei and colleagues’ aVr algorithm for the diagnosis of ventricular tachycardia, and a comparison of self-reported sensitivities, specificities, and test accuracies of the algorithms presented by Kindwall, Brugada, and Vereckei and their colleagues.   Key words: prolonged QT interval, supraventricular tachycardia, ventricular tachycardia, wide-complex tachycardias   This review contains 8 highly rendered figures, 8 tables, and 59 references.


2021 ◽  
pp. 126-130
Author(s):  
N. A. Skuratova ◽  
A. I. Zaryankina ◽  
A. A. Kozlovsky ◽  
S. S. Ivkina

The article presents a clinical case of a 16-year-old girl with clinical manifestations of congenital long QT interval syndrome in the form of syncope which were primarily diagnosed as epileptic syndrome for which the patient was taking anticonvulsant drugs having qualities of secondary prolongation of QT interval. At the same time, the data of family anamnesis (sudden death of the mother at a young age) in combination with typical manifestations of disease and electrocardiographic signs (prolonged QT interval measured from the standard electrocardiogram, paroxysms of spindle-shaped ventricular tachycardia accompanied with syncope conditions) made it possible to diagnose congenital long QT interval syndrome and implant an electric cardiac pacemaker.


1981 ◽  
Vol 102 (1) ◽  
pp. 16-24 ◽  
Author(s):  
George J. Taylor ◽  
Richard S. Crampton ◽  
Robert S. Gibson ◽  
Pamela T. Stebbins ◽  
Maria T.G. Waldman ◽  
...  

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