scholarly journals 947 Results after conservative surgery of stage II/III serous borderline ovarian tumors

Author(s):  
S Gouy ◽  
S Maria ◽  
A Maulard ◽  
M Faron ◽  
A Leary ◽  
...  
Author(s):  
Sebastien Gouy ◽  
Sophie Maria ◽  
Matthieu Faron ◽  
Amandine Maulard ◽  
Patricia Pautier ◽  
...  

2005 ◽  
Vol 97 (3) ◽  
pp. 845-851 ◽  
Author(s):  
Nurettin Boran ◽  
Aylin Pelin Cil ◽  
Gokhan Tulunay ◽  
Esmen Ozturkoglu ◽  
Sevgi Koc ◽  
...  

2016 ◽  
Vol 215 (6) ◽  
pp. 756.e1-756.e9 ◽  
Author(s):  
Dorella Franchi ◽  
Sara Boveri ◽  
Davide Radice ◽  
Rosalba Portuesi ◽  
Vanna Zanagnolo ◽  
...  

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15508-e15508
Author(s):  
Natasha Gercovich ◽  
Carlos Garcia Gerardi ◽  
Ernesto Gil Deza ◽  
Eduardo L. Morgenfeld ◽  
Edgardo G. J. Rivarola ◽  
...  

e15508 Background: Borderline ovarian tumors, also called low-malignancy potential tumors, are infrequent tumors present predominantly in pre-menopause women. Their evolution after surgical treatment is generally very good. The main objective of this paper is to show the evolution of a group of borderline tumors treated at our institution. Methods: Between January 1, 2000 and January 1, 2010, 36 patients diagnosed with ovarian borderline tumors were examined by two independent pathologists, according to the guidelines established by the USA Association of Directors of Anatomic and Surgical Pathology. These patients were followed at IOHM and comprise this paper’s study group. Results: Population Characteristics: Mean Age: 41 years (Range: 20-85). Affected Ovary (Right: 17 pts; Left: 14 pts; Both: 5 pts). Pathology: Mucinous (17 pts), Serous (16 pts), Clear, Brenner and Endometroid Cells (1 pt each). Stages: IA (24 pts), IB (5 pts), IC (2pts), IIIA (4 pts), IIIC (1 pt). Five patients presented non-invasive peritoneal implants and three presented positive peritoneal liquid. All patients were surgically treated: 28 with total anexohisterectomy (TAH) and 8 with unilateral ooforectomy. No patient was given any chemotherapy or radiotherapy treatment. Four patients did not attend follow-up consultations and were lost after 4, 6, 12 and 29 months with no evidence of disease (NED). Thirty-two patients were followed bi-annually during the first five years and annually thereafter. One patient became pregnant after the surgery. All patients are alive and NED with an average follow up of 50 months (range: 29-133). Conclusions: 1) Although half the cases in the study were under 35 years old, there were 12 tumors present in patients over 50 years of age and 1 borderline tumor present in an 85 year old patient. 2) Surgically treated ovarian borderline tumors have a high chance of being curable without the need of chemotherapy or radiotherapy. 3) Conservative surgery in young patients allows a conservation of fertility, provided they are subject to an adequate follow-up.


2000 ◽  
Vol 55 (7) ◽  
pp. 430-431
Author(s):  
Robert T. Morris ◽  
David M. Gershenson ◽  
Elvio G. Silva ◽  
Michele Follen ◽  
Mitchell Morris ◽  
...  

2020 ◽  
Author(s):  
Na Li ◽  
Jinhai Gou ◽  
Lin Li ◽  
Xiu Ming ◽  
Ting Wenyi Hu ◽  
...  

Abstract Purpose The study is aimed to evaluate the potential effect of clinicopathologic and surgical factors on the prognosis and fertile outcomes in the patients with borderline ovarian tumors. Patients and Methods We performed a retrospective analysis involving BOT patients who had underwent surgical procedures in West China Second University Hospital from January 2008 to January 2015 . The disease-free survival (DFS) outcomes and potential prognostic factors were evaluated using Kaplan-Meier method and Cox regression analysis, respectively. Furthermore, the fertile outcomes were analyzed using Pearson Χ2 and Fish correlation test. Results A total of 448 patients were included with a median age of 37.1 years and a median follow-up time of 113 months. Forty-two (11.6%) recurrences with the mean recurrence interval 80.2 months and four (0.9%) deaths were observed. One hundred and eighteen (26.3%) patients were underwent staging surgery and the remaining 330 (73.7%) patents underwent unstaged surgery. A total of 233 patients undergoing fertility sparing surgery (FSS) attempted to conceive and 92 (39.48%) of them achieved pregnancy. No statistically significant difference of fertile outcomes were found between staging surgery group or not (P=0.691). In univariate analyse, staging surgery was obviously associated with DFS (HR=2.191 P=0.005), but was not an independent prognostic factor (p=0.600) for DFS on multivariate analysis. The multivariate Cox analysis revealed that advanced FIGO stage (≥stage II), positive ascites\pelvic washings and laparotomy approach were independent prognostic factors for DFS in overall patients, whereas advanced stage (≥stage II), laparotomy approach, cystectomy-included procedure, invasive implants and bilateral tumors were independent prognostic factors for DFS in patients undergoing FSS. In addition, laparoscopy approach had better prognosis than laparotomy in patients of early stage (stage I) with fertility desire. Conclusion Patients with BOT fail to benefit from surgical staging in prognosis and fertile outcomes. Laparoscopy will be recommended to patients of stage I with fertility desire. Patients with fertility desire at advanced stage (≥stage II), invasive implants and bilateral tumors should pay more attention to the risk of recurrence and choose FSS carefully.


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