OP22 Hand Hygiene and absenteeism in primary schools; a Cluster Randomised Controlled Trial

2014 ◽  
Vol 68 (Suppl 1) ◽  
pp. A14.1-A14 ◽  
Author(s):  
AL Nicholson ◽  
RM Campbell ◽  
ST Brookes ◽  
CE Costelloe ◽  
CR Chittleborough ◽  
...  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Naomi E. Clarke ◽  
Dinh Ng-Nguyen ◽  
Rebecca J. Traub ◽  
Archie C. A. Clements ◽  
Kate Halton ◽  
...  

Abstract Background Current guidelines and targets for soil-transmitted helminth (STH) control focus on school-based deworming for school-age children, given the high risk of associated morbidity in this age group. However, expanding deworming to all age groups may achieve improved STH control among both the community in general and school-age children, by reducing their risk of reinfection. This trial aims to compare school-based targeted deworming with community-wide mass deworming in terms of impact on STH infections among school-age children. Methods The CoDe-STH (Community Deworming against STH) trial is a cluster-randomised controlled trial (RCT) in 64 primary schools in Dak Lak province, Vietnam. The control arm will receive one round of school-based targeted deworming with albendazole, while in the intervention arm, community-wide mass deworming with albendazole will be implemented alongside school-based deworming. Prevalence of STH infections will be measured in school-age children at baseline and 12 months following deworming. The primary outcome is hookworm prevalence in school-age children at 12 months, by quantitative PCR. Analysis will be intention-to-treat, with outcomes compared between study arms using generalised linear and non-linear mixed models. Additionally, cost-effectiveness of mass and targeted deworming will be calculated and compared, and focus group discussions and interviews will be used to assess acceptability and feasibility of deworming approaches. Individual based stochastic models will be used to predict the impact of mass and targeted deworming strategies beyond the RCT timeframe to assess the likelihood of parasite population ‘bounce-back’ if deworming is ceased due to low STH prevalence. Discussion The first large-scale trial comparing mass and targeted deworming for STH control in South East Asia will provide key information for policy makers regarding the optimal design of STH control programs. Trial registration ACTRN12619000309189.


2010 ◽  
Vol 14 (2) ◽  
pp. 219-226 ◽  
Author(s):  
Simon Murphy ◽  
GF Moore ◽  
K Tapper ◽  
R Lynch ◽  
R Clarke ◽  
...  

AbstractObjectiveThe present study evaluated the impact of a national school programme of universal free healthy breakfast provision in Wales, UK.DesignA cluster randomised controlled trial with repeated cross-sectional design and a 12-month follow-up. Primary outcomes were breakfast skipping, breakfast diet and episodic memory. Secondary outcomes were frequency of eating breakfast at home and at school, breakfast attitudes, rest-of-day diet and class behaviour.SettingPrimary schools in nine local education authority areas.SubjectsA total of 4350 students (aged 9–11 years) at baseline and 4472 at follow-up in 111 schools.ResultsStudents in intervention schools reported significantly higher numbers of healthy food items consumed at breakfast and more positive attitudes towards breakfast eating at 12 months. Parents in intervention schools reported significantly higher rates of consumption of breakfast at school and correspondingly lower rates of breakfast consumption at home. No other significant differences were found.ConclusionsThe intervention did not reduce breakfast skipping; rather, pupils substituted breakfast at home for breakfast at school. However, there were improvements in children’s nutritional intake at breakfast time, if not the rest of the day, and more positive attitudes to breakfast, which may have implications for life-course dietary behaviours. There was no impact on episodic memory or classroom behaviour, which may require targeting breakfast skippers.


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