Evaluation of language analysis to summarize the literature: a comparison to traditional meta-analysis in primary hip and knee surgery

2021 ◽  
pp. rapm-2021-103261
Author(s):  
Joshua Myszewski ◽  
Emily Klossowski ◽  
Kristopher M Schroeder

IntroductionSentiment analysis, by evaluating written wording and its context, is a growing tool used in computer science that can determine the level of support expressed in a body of text using artificial intelligence methodologies. The application of sentiment analysis to biomedical literature is a growing field and offers the potential to rapidly and economically explore large amounts of published research and characterize treatment efficacy.MethodsWe compared the results of sentiment analysis of 115 article abstracts analyzed in a recently published meta-analysis of peripheral nerve block usage in primary hip and knee arthroplasty to the conclusions drawn by the authors of the original meta-analysis.ResultsA moderately positive outlook supporting the utilization of regional anesthesia for hip and knee arthroplasty was found in the 115 articles that were included for analysis, with 46% expressing positive sentiment, 35% expressing neutral sentiment, and 19% of abstracts expressing negative sentiment. This was well aligned with the conclusions reached by a previous meta-analysis of the same articles.DiscussionSentiment analysis applied to the medical literature can rapidly evaluate large collections of published data and generate an impression of overall findings that are aligned with the findings of a traditional meta-analysis.

2018 ◽  
Vol 43 (6) ◽  
pp. 1283-1295 ◽  
Author(s):  
Sascha Karunaratne ◽  
Michael Duan ◽  
Evangelos Pappas ◽  
Brett Fritsch ◽  
Richard Boyle ◽  
...  

2021 ◽  
Author(s):  
Md Ariful Haque ◽  
Xiong Ying ◽  
Sayed Abdulla Jami ◽  
Ren YunFeng ◽  
Siam Al Mobarak ◽  
...  

Abstract Purpose: Knee arthroplasty and hip arthroplasty (THA) patients are susceptible to post-operative venous thromboembolism(VTE). Doctors are increasingly recommending the application of different thromboprophylaxis agents such as rivaroxaban. The agents are primarily effective in preventing thromboembolism after hip and knee arthroplasty. Similarly, recent research suggests aspirin as one of the cost-effective interventions for preventing thromboembolism. Accordingly, this meta-analysis aims to compare the effectiveness of Aspirin against Rivaroxaban for the prevention or treatment of thromboembolism following knee arthroplasty and knee arthroplasty.Methods: The researcher relied on electronic searches of about five databases. The database searches identified relevant studies used to extract meta-analyzed data and information. The databases included PubMed, Cinahl, Medicine, Cochrane Database of Systematic Reviews(CDSR), Pharma GKB, SAGE, from inception to December 2020.Results: Different studies from the five databases we are included in this study. The studies include 2257 in the aspirin group and 2337 in the rivaroxaban group. The result revealed no significant difference between Aspirin and Rivaroxaban for the treatment of venous thromboembolism.Conclusion: The meta-analysis result affirmed no statistically significant difference between Aspirin and Rivaroxaban in preventing venous thromboembolism, a joint arthroplasty, or hip fracture surgery. However, some health care professionals find aspirin a more effective, safe, convenient, and affordable alternative for preventing venous thromboembolism. Thus the meta-analysis recommends extensive randomized studies to confirm the stipulated outcomes.


CJEM ◽  
2007 ◽  
Vol 9 (06) ◽  
pp. 459-462 ◽  
Author(s):  
Clinton T. Forsythe ◽  
Michael E. Ernst

ABSTRACT Objective: The objective of this paper was to review the relation between fluoroquinolone (FQ) use and arthropathy in children. Methods: The biomedical literature from January 1980 to February 2007 was searched using PubMed. Key search terms included fluoroquinolones, arthropathy, tendinopathy and children. Literature was included if it was a clinical trial or meta-analysis examining the use of 1 or more FQs in a pediatric human population and if it had a primary outcome measure of reported incidence of arthropathy or tendinopathy. Articles were excluded if the primary outcome measure was efficacy of an FQ in a particular pediatric disease state, and evaluated safety was a secondary end point. Results: Data was reviewed from 4 large retrospective studies. Three of the 4 studies failed to find a significant link between musculoskeletal injury and FQ treatment. One study reported a correlation between use of pefloxacin and arthropathy, but the authors' conclusions supported the use of FQs in select pediatric cases. Conclusion: Arthropathy that occurs as a result of FQ use in children has not been adequately supported by published data from safety trials in human children. Concerns about arthropathy with FQs should not preclude their use by emergency physicians when appropriate and necessary in pediatric patients.


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