In this paper we prove the existence and uniqueness of weak solutions of the mixed problem for the nonlinear hyperbolic-parabolic equation(K1(x,t)u′)′+K2(x,t)u′+A(t)u+F(u)=fwith null Dirichlet boundary conditions and zero initial data, whereF(s)is a continuous function such thatsF(s)≥0,∀s∈Rand{A(t);t≥0}is a family of operators ofL(H01(Ω);H−1(Ω)). For the existence we apply the Faedo-Galerkin method with an unusual a priori estimate and a result of W. A. Strauss. Uniqueness is proved only for some particular classes of functionsF.