DABCO as a green catalyst for the synthesis of pyranoquinoline derivatives

2017 ◽  
Vol 95 (5) ◽  
pp. 601-604 ◽  
Author(s):  
Ramin Ghorbani-Vaghei ◽  
Farid Rahmatpour ◽  
Narges Sarmast ◽  
Jafar Mahmoudi ◽  
Azadeh Shahriari
Keyword(s):  
One Pot ◽  
Green Catalyst ◽  
One Pot Synthesis ◽  
Convenient Synthesis ◽  
High Yields

In this study, a rapid and convenient synthesis of quinolines was developed. The reaction involves a one-pot synthesis of pyranoquinoline derivatives from aldehyde, malonitrile, and 8-hydroxyquinoline using DABCO as a catalyst at 80 °C in H2O/EtOH as the solvent in good to high yields.

scholarly journals A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

SynOpen ◽  
2018 ◽  
Vol 02 (02) ◽  
pp. 0207-0212 ◽  
Author(s):  
Feize Liu ◽  
Xueling Hou ◽  
Li Nie ◽  
Khurshed Bozorov ◽  
Michael Decker ◽  
...  
Keyword(s):  
Aromatic Aldehydes ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Synthesis ◽  
Three Component Reaction ◽  
Simple Protocol ◽  
High Yields

An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and amines.

An Expeditious One-Pot Three-Component Synthesis of 4-Aryl-3,4-dihydrobenzo[g] quinoline-2,5,10(1H)-triones under Green Conditions

2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani
Keyword(s):  
Reaction Medium ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
First Time ◽  
Green Conditions

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

scholarly journals A New and Efficient One-pot Synthesis of Trialkyl 6-tert-Butylamino-2H-pyran-2-one-3,4,5-tricarboxylates

1999 ◽  
Vol 23 (6) ◽  
pp. 368-369
Author(s):  
Issa Yavari ◽  
Abbas Ali Esmaili ◽  
Sakineh Asghari ◽  
Hamid Reza Bijanzadeh
Keyword(s):  
One Pot ◽  
Tert Butyl ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
High Yields

The highly reactive 1:1 intermediate produced in the reaction between tert-butyl isocyanide and dialkyl acetylenedicarboxylates is trapped by dialkyl 2-bromomalonates to yield the title compounds in fairly high yields.

One-pot synthesis of β-diketimine ligands

2010 ◽  
Vol 88 (10) ◽  
pp. 1040-1045 ◽  
Author(s):  
Ibrahim El-Zoghbi ◽  
Aysha Ased ◽  
Paul O. Oguadinma ◽  
Ekou Tchirioua ◽  
Frank Schaper
Keyword(s):  
Hydrochloric Acid ◽  
Water Use ◽  
Minimum Amount ◽  
One Pot ◽  
One Pot Synthesis ◽  
Toluenesulfonic Acid ◽  
High Yields ◽  
Optimized Conditions

Symmetric N,N′-dialkyl-2-amino-4-imino-pent-2-enes (nacnacRH) can be prepared in high yields in a simple one-pot reaction from acetylacetone and 2 equiv. of amine. Optimized conditions require the azeotropic removal of water, use of a minimum amount of solvent, and of 1 equiv. of acid. Either para-toluenesulfonic acid, hydrochloric acid, or a mixture of both can be employed, with the latter being most advantageous. Symmetric nacnacRH are thus obtained in higher than 95% purity and with 65% yield for R = Me and 80%–95% yields for R = n-Pr, i-Pr, i-Bu, Bn, Cy, and (+)-CH(Me)Ph.

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

Polyethylene glycol-mediated synthesis of decahydroacridine-1,8-diones catalyzed by ceric ammonium nitrate

2010 ◽  
Vol 64 (6) ◽  
Author(s):  
Mazaahir Kidwai ◽  
Divya Bhatnagar
Keyword(s):  
Polyethylene Glycol ◽  
Ammonium Nitrate ◽  
Effective Medium ◽  
Ceric Ammonium Nitrate ◽  
One Pot ◽  
One Pot Synthesis ◽  
High Yields

AbstractPolyethylene glycol was found to be an inexpensive non-toxic and effective medium for one pot synthesis of high yields of decahydroacridine-1,8-diones in the presence of ceric ammonium nitrate as the catalyst. Moreover, the solvent can be recovered and reused.

scholarly journals Calcium hydroxide: An efficient and mild base for one-pot synthesis of curcumin and it’s analogues

2013 ◽  
Vol 6 (1) ◽  
pp. 150-156
Author(s):  
Pramod S. Kulkarni ◽  
Dasharath D. Kondhare ◽  
Ravi Varala ◽  
Pudukulathan K. Zubaidha
Keyword(s):  
Calcium Hydroxide ◽  
Aromatic Aldehyde ◽  
One Pot ◽  
Acetyl Acetone ◽  
One Pot Synthesis ◽  
The One ◽  
High Yields

Abstract Calcium hydroxide was found to be an efficient mild base for the one-pot synthesis of curcumin and its analogues obtained by condensation of one equivalent of acetyl acetone with two equivalents of corresponding aromatic aldehyde. The present protocol offers various advantages such as high yields, inexpensive easily available mild base, easy workup and eco-friendly method.

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