scholarly journals A 13-week low glycemic load diet and lifestyle modification program combining low glycemic load protein shakes and targeted nutraceuticals improved weight loss and cardio-metabolic risk factors

2017 ◽  
Vol 95 (12) ◽  
pp. 1414-1425 ◽  
Author(s):  
Clinton J. Dahlberg ◽  
Joseph J. Ou ◽  
John G. Babish ◽  
Joseph J. Lamb ◽  
Sarah Eliason ◽  
...  

An open-label, randomized, exploratory study of 44 healthy overweight subjects with cardio-metabolic syndrome (CMS) risk factors was conducted to assess the safety, tolerability, and efficacy of a proprietary lifestyle modification program without (DIET) and with (PROG) targeted nutraceutical supplementation, including phytosterols, antioxidants, probiotics, fish oil, berberine, and soy, pea, and whey proteins over 13 weeks. Key metrics were recorded at baseline and weeks 9 and 13. For the DIET and PROG groups, compliance was 85% and 86%, respectively, with no adverse events related to the diet or supplements. Twelve subjects discontinued participation before week 9 for reasons unrelated to the study. PROG subjects experienced greater decreases (p < 0.05) than DIET in body mass, fat mass, total cholesterol, LDL cholesterol, TG, cholesterol / HDL ratio, TG/HDL ratio, apolipoprotein B / apolipoprotein A1 ratio, and hs-CRP. The Framingham 10-year cardiovascular disease risk score decreased by 40% (p < 0.01) in the PROG arm versus no change for the DIET arm. As a pilot study, it was not possible to state whether the observed effects were the result of nutraceutical supplementation alone or the result of additive or synergistic interactions among diet, lifestyle modifications, and nutraceutical supplementation. Moreover, individuals with CMS risk factors following a lifestyle modification program received additional health benefits from targeted nutraceutical supplementation.

2019 ◽  
Vol 68 (3) ◽  
pp. 109-120 ◽  
Author(s):  
Soo Hee Woo ◽  
Eui Geum Oh ◽  
Kyung-SOO Kim ◽  
Sang Hui Chu ◽  
Gwang Suk Kim ◽  
...  

Cardiovascular disease is a leading cause of mortality in the United States. This study examined the cardiovascular disease risk factors and health beliefs of workers for the purpose of developing a social network service (SNS)-based (e.g., Facebook and KakaoTalk) lifestyle-modification program for workers. Participants included 68 hospital workers (aged 25-60 years), with more than two metabolic syndrome or cardiovascular disease risk factors. Participants were randomly assigned to one of three groups: SNS intervention group ( n = 23), education-only intervention group ( n = 19), or nonintervention group ( n = 26). Data were collected to compare changes in risk indicators according to the intervention method and time and analyzed using repeated-measures analyses of variance. Compared to the education and nonintervention groups, the SNS intervention group demonstrated significant improvements in waist circumference, body mass index, total cholesterol, low-density lipoprotein cholesterol, health promotion behaviors, and self-efficacy. This type of program has potential for allowing occupational health professionals to work with workers to improve lifestyle behaviors that promote health and reduce the risk of cardiovascular disease.


Author(s):  
Jordan Sarver ◽  
Janet Simon ◽  
David Drozek

Abstract Background: Cardiovascular disease (CVD) is the second leading cause of death inPeru, behind respiratory disease. e purpose of this study was to better quantify thelevel of CVD risk in resource poor communities of northern Lima. Methods and findings: Data was collected from urban, impoverished communitiesof Lima, Peru consisting of demographics, dietary recall, glycosylated hemoglobin,lipids and body mass index. Conclusion: Cardiovascular disease risk factors are prevalent with alarming percentagesof the population demonstrating abnormal values in most variables examined, andincreased risk utilizing the risk calculator. Higher levels of modifiable CVD risk factorsexist in resource poor communities in northern Lima, Peru. Lifestyle modification focusedon a plant-based diet might be an affordable, cost-effective approach to reducingCVD risk.  


2005 ◽  
Vol 81 (5) ◽  
pp. 976-982 ◽  
Author(s):  
Cara B Ebbeling ◽  
Michael M Leidig ◽  
Kelly B Sinclair ◽  
Linda G Seger-Shippee ◽  
Henry A Feldman ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Ju-Sheng Zheng ◽  
Jing Yang ◽  
Tao Huang ◽  
Xiao-Jie Hu ◽  
Ming Luo ◽  
...  

Objectives. To elucidate whether consumption of two Chinese liquors, tea-flavor liquor (TFL) and traditional Chinese liquor (TCL) have protective effects on cardiovascular disease (CVD) risk factors in healthy human subjects.Methods. Forty-five healthy subjects (23 men, 22 women), aged 23–28, were recruited and randomized into two groups: TFL and TCL, and consumed 30 mL/day (45% (v/v) alcohol) of either liquor for 28 days.Results. Serum high-density lipoprotein cholesterol/low-density lipoprotein cholesterol (HDL-C/LDL-C) and apolipoprotein A1 were significantly increased, and total cholesterol (TC) and TC/HDL-C were significantly decreased after the intervention in both groups (P<0.05). Serum uric acid (P=0.004for TFL,P=0.001for TCL), glucose (P<0.001for TFL,P<0.001for TCL) and endothelial adhesion molecules (P<0.05) were significantly decreased after the intervention. ADP-induced whole blood platelet aggregation was also significantly decreased after the intervention in both TFL and TCL groups (P<0.05).Conclusions. TFL and TCL consumption had protective effects on CVD risk factors in young humans. However, the results were valid only for 28 days, and that the possibility of adverse effect (liver, kidney) of chronic alcohol consumption should be considered.


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