Effect of Metopirone on Pituitary–Interrenal Function in Two Teleosts, Sockeye Salmon (Oncorhynchus nerka) and Rainbow Trout (Salmo gairdneri)

1968 ◽  
Vol 25 (7) ◽  
pp. 1465-1474 ◽  
Author(s):  
Ulf H. M. Fagerlund ◽  
J. R. McBride ◽  
Edward M. Donaldson
Keyword(s):  
Rainbow Trout ◽  
Sockeye Salmon ◽  
Oncorhynchus Nerka ◽  
Inhibitory Effect ◽  
Salmo Gairdneri ◽  
Pars Distalis ◽  
Marked Inhibitory Effect ◽  
Interrenal Cells ◽  
Rostral Region ◽  
Low Dosage

Metopirone (SU 4885), an inhibitor of 11β-hydroxylation of adrenocorticosteroids, was administered intramuscularly to adult castrated sockeye salmon (Oncorhynchus nerka) and intact rainbow trout (Salmo gairdneri). Marked hypertrophy of interrenal cells pointed to an increase in the activity of the interrenal tissue of both species. Increased cortisol concentrations in trout at low dosage levels of metopirone suggested that the drug was stressful. However, decreased concentrations at higher dosage levels in trout, and decreased cortisol concentrations in all salmon indicated that the drug was also exerting a marked inhibitory effect on 11β-hydroxylation. In salmon, a repository ACTH preparation (acthar) brought about interrenal hypertrophy similar to that produced by metopirone. Metopirone also induced degranulation and hyperplasia of the cells of the palisade-like layer in the rostral region of the pars distalis in both species of fish. These cells were the only cell type of the pars distalis that were stained with lead-haematoxylin. The evidence indicates that they are the corticotrops.

Factors Affecting Rainbow Trout (Salmo gairdneri) Predation on Migrant Fry of Sockeye Salmon (Oncorhynchus nerka)

1976 ◽  
Vol 33 (1) ◽  
pp. 19-24 ◽  
Author(s):  
R. M. Ginetz ◽  
P. A. Larkin
Keyword(s):  
Rainbow Trout ◽  
Sockeye Salmon ◽  
Oncorhynchus Nerka ◽  
Development Stage ◽  
Salmo Gairdneri ◽  
Factors Affecting ◽  
Light Intensities ◽  
Salmon Fry ◽  
Lower Stream ◽  
Downstream Movement

Predation of rainbow trout (Salmo gairdneri) on migrant sockeye salmon (Oncorhynchus nerka) fry in experimental streams was higher on fry at an earlier development stage, in moonlight by contrast to cloudy night light intensities, at lesser turbidities, and at lower stream velocities. At dusk light intensities, from.05 to.30 ft-c, mortality from predation was inversely related to light intensity. The longer the period of exposure of fry to naturally declining light intensities prior to downstream movement, the lower was the loss to predators. Exposure of predators to high light intensities prior to the downstream movement of fry resulted in decreased fry mortality. Fry that had survived exposure to predators in an experimental stream 1 and 2 days previous were less vulnerable to predation than "naive" fry. Successive exposures further decreased the loss to predation. Fry enumerated at a counting fence suffered less predation than fry not enumerated. Experienced fry moved downstream more rapidly than naive fry.In laboratory aquaria, experienced fry formed compact schools prior to and in response to stimuli, while naive fry formed loose schools or did not school. Experienced fry were less active in responding to stimuli. Enumerated fry resembled experienced fry; nonenumerated fry resembled naive fry.Various techniques of enhancing sockeye salmon fry survival during downstream migration are suggested by these results.

Occurrence of the eyefluke, Diplostomum (Diplostomum) baeri bucculentum Dubois et Rausch, 1948, in salmonid fishes of northern British Columbia

1985 ◽  
Vol 63 (2) ◽  
pp. 396-399 ◽  
Author(s):  
Hilda Lei Ching
Keyword(s):  
Rainbow Trout ◽  
Chinook Salmon ◽  
Sockeye Salmon ◽  
Lake Trout ◽  
Infected Fish ◽  
Salmo Gairdneri ◽  
Coregonus Clupeaformis ◽  
Lake Whitefish ◽  
Dolly Varden Salvelinus Malma ◽  
Prosopium Williamsoni

As a result of experimental infections in chicks, diplostomula found in the retina of chinook salmon from the Nechako River were identified as Diplostomum (Diplostomum) baeri bucculentum. Eyeflukes in other salmonids were considered to be the same species based on similar measurements and site in the eyes. These eyeflukes varied in prevalence and mean intensity in seven salmonid species surveyed in nine localities in 1979–1981. The following fish were sampled: rainbow trout (Salmo gairdneri), 505; mountain whitefish (Prosopium williamsoni), 334; lake whitefish (Coregonus clupeaformis), 32; Dolly Varden (Salvelinus malma), 66; lake trout (S. namaycush), 13; kokanee or sockeye salmon (Oncorhynchus nerka), 323; and chinook salmon (O. tshawytscha), 164. Eyeflukes had prevalences ranging from 84 to 100% in six lakes, 64% in the river, 53% in one reservoir site, and a prevalence of 15% in the other reservoir site. Mountain and lake whitefishes had high mean intensities while kokanee had low mean intensities. Correlation of increased intensity with increased fish size was significant for 6 of 27 samples. Four samples of lake whitefish, mountain whitefish, rainbow trout, and chinook salmon showed significant asymmetry when numbers of diplostomula were compared between eyes. More of the heavily infected fish showed asymmetry than did the lightly infected fish.

The Pigments of Salmon

1937 ◽  
Vol 3 (5) ◽  
pp. 469-472 ◽  
Author(s):  
Basil E. Bailey
Keyword(s):  
Sockeye Salmon ◽  
Oncorhynchus Nerka ◽  
Salmo Gairdneri ◽  
Carotenoid Pigments ◽  
Red Pigments ◽  
Red Muscle

The red colour of the muscle flesh of the sockeye salmon (Oncorhynchus nerka) is due to the presence of two carotenoid pigments both of which have properties similar to those of astacin. Two red pigments were also found in the red muscle flesh of the steelhead salmon (Salmo gairdneri).

Characterization and Subcellular Localization of Leucine Aminonaphthylamidase (LAN) in Rainbow Trout (Salmo gairdneri)

1975 ◽  
Vol 32 (8) ◽  
pp. 1289-1295 ◽  
Author(s):  
G. R. Bouck ◽  
P. W. Schneider Jr. ◽  
Janet Jacobson ◽  
R. C. Ball
Keyword(s):  
Enzyme Activity ◽  
Rainbow Trout ◽  
Reaction Time ◽  
Blood Plasma ◽  
Substrate Concentration ◽  
Room Temperature ◽  
Diagnostic Value ◽  
Inhibitory Effect ◽  
Salmo Gairdneri ◽  
Body Temperatures

LAN analyses appear to have diagnostic value in fish pathobiology and studies were undertaken to determine optima for substrate concentration, pH, reaction time, temperature, and buffer ions. Citrate ion did not inhibit LAN at anticoagulant levels, but cyanide, pyrophosphate, and EDTA had an inhibitory effect. Storage of samples at —10 and 1 C resulted in small but significant reductions of LAN activity, while at room temperature enzyme activity was rapidly lost. LAN activity was distributed among liver fractions as follows: microsomes, 12%; mitochondria, 9%; cellular sap, 37%; other, 50%. Three isozymes of LAN were found. Blood plasma contained significant amounts of LAN activity which was significantly higher in cold- than in warm-acclimated fish. However, these LAN levels were comparable when their activity was extrapolated to body temperatures.

Sublethal Effects of Bleached Kraft Pulp Mill Effluent on Respiration and Circulation in Sockeye Salmon (Oncorhynchus nerka)

1973 ◽  
Vol 30 (3) ◽  
pp. 369-377 ◽  
Author(s):  
John C. Davis
Keyword(s):  
Oxygen Uptake ◽  
Sockeye Salmon ◽  
Sublethal Effects ◽  
Oncorhynchus Nerka ◽  
Gas Diffusion ◽  
Arterial Oxygen ◽  
Salmo Gairdneri ◽  
Similar Response ◽  
Initial Exposure ◽  
Cough Frequency

Sublethal effects of aerated neutralized, filtered, full bleach kraft mill effluent (BKME) on circulation and respiration of Pacific salmon were examined. Ventilatory water flow, oxygen uptake, cough frequency, and buccal pressure increased in a group of 19 sockeye salmon, Oncorhynchus nerka, 207–321 g, at 10.5 ± 0.5 C, upon initial exposure to sublethal BKME concentrations. The threshold concentration for these responses appreared to be around 20% of the 4 day LC50 (static bioassay).Following overnight exposure to BKME, ventilatory volume, oxygen uptake rate, cough frequency, and oxygen utilization tended to approach pre-exposure levels, particularly at the higher sublethal contractions. Changing effluent toxicity, acclimation phenomena, or physiological adjustment are discussed as possible explanations for these results.Measures of arterial oxygen tension in sockeye salmon indicated that arterial tension declines rapidly and remains depressed following up to 24 hr exposure to BKME (33–47% of 4 day LC50). On the average this decline represented a 20% decrease in oxygen saturation of the blood. Decreased arterial PO2 may be due to mucous production at the gills and resulting gas diffusion problems, as well as abnormalities in ventilation. Reduction in scope for activity might result from impaired oxygen uptake at the gills. A similar response was observed in rainbow trout, Salmo gairdneri.

Histological Effects of 11-Ketotestosterone, 17α-Methyltestosterone, Estradiol, Estradiol Cypionate, and Cortisol on the Interrenal Tissue, Thyroid Gland, and Pituitary Gland of Gonadectomized Sockeye Salmon (Oncorhynchus nerka)

1971 ◽  
Vol 28 (4) ◽  
pp. 477-484 ◽  
Author(s):  
A. P. van Overbeeke ◽  
J. R. McBride
Keyword(s):  
Thyroid Gland ◽  
Sex Steroids ◽  
Sockeye Salmon ◽  
Marked Effect ◽  
Anterior Part ◽  
Oncorhynchus Nerka ◽  
Control Fish ◽  
Slight Reduction ◽  
Pars Distalis ◽  
Visible Effect

Effects of two androgens, two estrogens, and cortisol in gonadectomized sockeye salmon (Oncorhynchus nerka) were investigated. Males were injected with 11-ketotestosterone, 17α-methyltestosterone, or cortisol for 4 or 7 weeks. Females were injected with estradiol, estradiol cypionate, or cortisol for 8 weeks.Both the androgens and the estrogens caused interrenal hypertrophy. The effect of 17α-methyltestosterone was stronger than that of 11-ketotestosterone, and of the two estrogens used, estradiol cypionate exerted the most marked effect. Cortisol brought about a slight atrophy of the interrenal tissue.A pronounced histological activation of the small thyroid follicles was induced by the two androgens. The estrogens exerted no visible effect on the thyroid gland, and cortisol treatment caused a slight reduction in the height of the follicular epithelium.In the gonadectomized control fish of both sexes, gonadotrophs were small and practically all devoid of granules. All four sex steroids induced the appearance of many granulated PAS-positive gonadotrophs, particularly in the anterior part of the proximal pars distalis. This effect is considered on activation of the gonadotrophs. Cortisol administration induced pronounced degranulation and atrophy of the corticotrophs and this effect was strongest in the males. Neither the androgens nor the estrogens visibly affected the corticotrophs.

On the developmental pathway to nonanadromy in sockeye salmon, Oncorhynchus nerka

1994 ◽  
Vol 72 (3) ◽  
pp. 397-405 ◽  
Author(s):  
Chris J. Foote ◽  
Ian Mayer ◽  
Chris C. Wood ◽  
W. Craig Clarke ◽  
J. Blackburn
Keyword(s):  
Gene Flow ◽  
Seasonal Cycle ◽  
Sockeye Salmon ◽  
Oncorhynchus Nerka ◽  
Rapid Development ◽  
Inhibitory Effect ◽  
Developmental Pathway ◽  
Early Maturation ◽  
Recent Gene Flow ◽  
And Migration

The evolution of nonanadromous forms of salmonids has been linked to adaptive similarities between migration to the sea and migration to lakes, and to inhibition of smoltification by rapid development rates and early maturation. We examined the seasonal cycle of seawater adaptability in a landlocked (10 000 years) population of kokanee, Oncorhynchus nerka, to determine if the typical anadromous cycle persists in the absence of recent gene flow from sockeye salmon, as would be expected if components of smoltification are beneficial to a lacustrine existence. We also monitored the effects of maturation on seawater adaptability, to determine if they had an inhibitory effect on smoltification, as would be expected if a developmental conflict was responsible for the evolution of nonanadromous forms. Maturation was measured through the growth of gonadal tissue and the increase in circulating testosterone and 11-ketotestosterone. Landlocked kokanee showed the seawater adaptability cycle typical of sockeye salmon, and maturation had no inhibitory effect on seawater adaptability until near, or at, full maturity. We conclude that at least some components of smoltification must be beneficial to a life in lakes to account for the continued maintenance of the cycle. Further, rapid development and maturation on their own do not appear to account for the evolution of nonanadromous populations of O. nerka.

Molybdenum Concentrations in Tissues of Rainbow Trout (Salmo gairdneri) and Kokanee Salmon (Oncorhynchus nerka) from Waters Differing Widely in Molybdenum Content

1973 ◽  
Vol 30 (6) ◽  
pp. 841-842 ◽  
Author(s):  
James V. Ward
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Nerka ◽  
Weight Basis ◽  
Molybdenum Content ◽  
Salmo Gairdneri ◽  
Kokanee Salmon ◽  
Water Fish ◽  
Wet Weight ◽  
Molybdenum Concentration

Concentrations of molybdenum in tissues of rainbow trout (Salmo gairdneri) from three waters increased only slightly with increase in molybdenum concentration of the water. Fish from high (300 ppb) molybdenum water had mean concentrations of 13–332 ppb on a wet-weight basis; those from low (6 ppb) molybdenum water, 10–146 ppb; and those from trace molybdenum water, 5–118 ppb. Rainbow trout exhibited generally higher molybdenum concentrations than did kokanee salmon (Oncorhynchus nerka) in high molybdenum water. A possible plateau mechanism concerning molybdenum accumulation by salmonids is discussed.

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