Effects of Long-Term Tennis Playing on the Muscle-Bone Relationship in the Dominant and Nondominant Forearms

The relationship between muscle strength and bone mineral density illustrates the positive effect of mechanical loading on bone. But local and systemic factors may affect both muscle and bone tissues. This study investigated the effects of long-term tennis playing on the relationship between lean tissue mass and bone mineral content in the forearms, taking the body dimensions into account. Fifty-two tennis players (age 24.2 ± 5.8 yrs, 16.2 ± 6.1 yrs of practice) were recruited. Lean tissue mass (LTM), bone area, bone mineral content (BMC), and bone mineral density were measured at the forearms from a DXA whole-body scan. Grip strength was assessed with a dynamometer. A marked side-to-side difference (p < 0.0001) was found in favor of the dominant forearm in all parameters. Bone area and BMC correlated with grip strength on both sides (r = 0.81-0.84, p < 0.0001). The correlations were still significant after adjusting for whole-body BMC, body height, or forearm length. This result reinforced the putative role of the muscles in the mechanical loading on bones. In addition, forearm BMC adjusted to LTM or grip strength was higher on the dominant side, suggesting that tennis playing exerts a direct effect on bone. Key words: bone mineral content, muscle strength, unilateral loading, mechanical stress, absorptiometry

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Bone and Lean Tissue Changes Following Cranial Cruciate Ligament Transection and Stifle Stabilization

Journal of the American Animal Hospital Association ◽

10.5326/0420127 ◽

2006 ◽

Vol 42 (2) ◽

pp. 127-135 ◽

Cited By ~ 10

Author(s):

David A. Francis ◽

Darryl L. Millis ◽

Laurie L. Head

Keyword(s):

Bone Mineral Content ◽

Bone Mineral ◽

Mineral Content ◽

Cruciate Ligament ◽

Distal Tibia ◽

Significant Loss ◽

Mineral Density ◽

Lean Tissue ◽

Tissue Mass ◽

Cranial Cruciate Ligament

Following cranial cruciate ligament transection and extracapsular stabilization, dual-energy X-ray absorptiometry was used to analyze bone mineral content and lean tissue mass in the surgical and nonsurgical legs (n=14) at 0, 2, 4, and 8 weeks, and to evaluate bone mineral content and bone mineral density (BMD) of the proximal, mid-, and distal tibia of both the surgical and nonsurgical legs (n=15) at 0, 5, and 10 weeks. There was significant loss of bone mineral content and lean tissue in the surgical leg compared to the nonsurgical leg. Significant loss in bone mineral content and BMD was detected in the tibia of the surgical leg and was most pronounced in the metaphyseal region.

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Abstract P615: Stress-Induced Changes in Total Bone Mineral Content and Total Bone Mineral Density due to Activation of the Renin-Angiotensin-Aldosterone System in Adolescent Females

Hypertension ◽

10.1161/hyp.68.suppl_1.p615 ◽

2016 ◽

Vol 68 (suppl_1) ◽

Author(s):

Vishwajeeth Pasham ◽

Deborah Stewart ◽

Laura Carbone ◽

Gregory A Harshfield

Keyword(s):

Bone Mineral Density ◽

Bone Mineral Content ◽

Bone Metabolism ◽

Bone Mineral ◽

Mineral Content ◽

Mineral Density ◽

Renin Angiotensin Aldosterone System ◽

Total Bone Mineral Density ◽

Total Bone Mineral Content ◽

The Relationship

Background: Previous literature has shown a strong negative effect of angiotensin II (ANGII) on bone metabolism within mouse models. Additionally, psychological stress has been associated with activation of the renin-angiotensin-aldosterone system (RAAS). Stress has also been related to lower total bone mineral density (TBMD). However, there is controversy in the literature examining the relationship between the RAAS and bone metabolism within humans and stress has not been considered as a direct link between these systems. Purpose: We aimed to examine the relationship between stress-induced RAAS activation and TBMD and total bone mineral content (TBMC). Methods: Participants were placed on a sodium controlled diet for three days. Participants then underwent two hours rest, one hour mental stressor, and two hours recovery with hourly collections of blood/urine samples. Renin, ANGII, aldosterone, TBMD and TBMC were measured. Results: This study recruited 586 adolescents (mean age 16±1.116) with 51% women and 62% African-American and 38% Caucasian. Overall, relationships were observed between ANGII and aldosterone, and TBMC and TBMD controlling for age, race, and BMI. During stress, aldosterone was related to TBMD (r=-.150, p<0.05) and ANGII was related to TBMC (r=-.156, p<0.05) and TBMD (r=-.139, p<0.05). When comparing males and females, only females demonstrated a relationship between TBMC and ANGII in response to stress (stress: r=-.229, p<0.05; post-stress: r=-.277, p<0.01) and between aldosterone and TBMC (stress: r=-.199, p<0.05) and TBMD (stress: r=-.250, p<0.01). Renin was not significantly correlated with TBMD nor TBMC in any population. Conclusion/Interpretations: These data suggest that stress-induced RAAS activation may be associated with lower TBMD and TBMC in girls. Despite small correlations, consistency across multiple measures of RAAS activation being apparent in adolescents is significant. This observation may indicate that stress activation of RAAS contributes to bone remodeling in early life.

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Explore Upper Limits of Bone Mineral Content And Density In Humans: A Study On Japanese Collegiate Sumo Wrestlers

10.21203/rs.3.rs-1001814/v1 ◽

2021 ◽

Author(s):

Taishi Midorikawa ◽

Suguru Torii ◽

Megumi Ohta ◽

Shizuo Sakamoto

Keyword(s):

Body Weight ◽

Bone Mineral Content ◽

Bone Mineral ◽

Fat Mass ◽

Mineral Content ◽

Mineral Density ◽

Tissue Mass ◽

X Ray ◽

Upper Limit ◽

Upper Limits

Abstract The purpose of this study was to explore the upper limit of total bone mineral content (BMC, kg) and bone mineral density (BMD, g/cm2) in humans by estimating body composition of Sumo wrestlers. A total of 54 male college Sumo wrestlers were recruited for the study and assigned to 2 groups according to body weight (middleweight, 85-115 kg, n = 23 and heavyweight, >115 kg, n = 31). BMC, BMD, fat mass and lean soft tissue mass (LSTM) were measured using dual-energy X-ray absorptiometry (DXA) for the total and appendicular regions. Heavyweight Sumo wrestlers had significantly greater body weight, fat mass, and LSTM compared to middleweight Sumo wrestlers. Mean total BMC was significantly larger in heavyweight than middleweight Sumo wrestlers, respectively (The highest value was 4.16 kg.). Total BMD was significantly higher in heavyweight compared to middleweight Sumo wrestlers (The highest value was 1.59 g/cm2.), and was significantly correlated with body weight, but not with fat mass and LSTM. Based on the present and previous studies, the upper limit of total BMC and BMD in humans with 150 kg bodyweight might be around 5.0 kg and 1.60 g/cm2.

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Daily Treatment with Human Recombinant Parathyroid Hormone-(1–34), LY333334, for 1 Year Increases Bone Mass in Ovariectomized Monkeys*

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem.84.10.6039 ◽

1999 ◽

Vol 84 (10) ◽

pp. 3757-3763 ◽

Cited By ~ 1

Author(s):

Robert Brommage ◽

Charlotte E. Hotchkiss ◽

Cynthia J. Lees ◽

Melanie W. Stancill ◽

Janet M. Hock ◽

...

Keyword(s):

Bone Mass ◽

Bone Mineral Content ◽

Bone Mineral ◽

Mineral Content ◽

Proximal Tibia ◽

Whole Body ◽

Mineral Density ◽

Increase Bone Mass ◽

Skeletal Effects ◽

Body Bone

AbstractPTH stimulates bone formation to increase bone mass and strength in rats and humans. The aim of this study was to determine the skeletal effects of recombinant human PTH-(1–34) [rhPTH-(1–34)] in monkeys, as monkey bone remodeling and structure are similar to those in human bone.Adult female cynomolgus monkeys were divided into sham-vehicle (n= 21), ovariectomized (OVX)-vehicle (n = 20), and OVX groups given daily sc injections of rhPTH-(1–34) at 1 (n = 39) or 5 (n = 41) μg/kg for 12 months. Whole body bone mineral content was measured, as was bone mineral density (BMD) in the spine, proximal tibia, midshaft radius, and distal radius. Serum and urine samples were also analyzed. rhPTH-(1–34) treatment did not influence serum ionized Ca levels or urinary Ca excretion, but depressed endogenous PTH while increasing serum calcitriol levels. Compared to that in the OVX group, the higher dose of rhPTH-(1–34) increased spine BMD by 14.3%, whole body bone mineral content by 8.6%, and proximal tibia BMD by 10.8%. Subregion analyses suggested that the anabolic effect of rhPTH-(1–34) on the proximal tibia was primarily in cancellous bone. Similar, but less dramatic, effects on BMD were observed with the lower dose of rhPTH-(1–34). Daily sc rhPTH-(1–34) treatment for 1 yr increases BMD in ovariectomized monkeys without inducing sustained hypercalcemia or hypercalciuria.

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