Isolation and characterization of a cytolysin produced by Vibrio cholerae serogroup non-O1
1985 ◽
Vol 31
(8)
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pp. 711-720
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Keyword(s):
A thermolabile toxin (molecular weight, 52 711; isoelectric point, 8.65) produced by a clinical isolate of Vibrio cholerae serogroup non-O1 was cytotoxic for Y-1 mouse adrenal cells and Chinese hamster ovary cells. The toxin lysed rabbit red blood cells and produced a hemorrhagic zone in rabbit skin. When injected intravenously into adult mice, the cytolysin was rapidly lethal and caused fluid accumulation in both 5- and 18-h rabbit ileal loops. Strains of V. cholerae that produced cytolysin but no cholerae enterotoxin were able to cause fluid accumulation in rabbit intestinal loops.
1979 ◽
Vol 101
(1)
◽
pp. 149-156
◽
1975 ◽
Vol 86
(2)
◽
pp. 253-260
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1986 ◽
Vol 261
(13)
◽
pp. 5790-5794
◽
1986 ◽
Vol 1
(2)
◽
pp. 139-145
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1992 ◽
Vol 267
(7)
◽
pp. 4889-4896
◽
1979 ◽
Vol 98
(3)
◽
pp. 459-468
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1993 ◽
Vol 268
(10)
◽
pp. 7276-7282