THE EFFECT OF NECROGENIC DIETS ON THE ACTIVITIES OF CERTAIN ENZYME SYSTEMS IN THE RED BLOOD CELLS OF RATS

1964 ◽  
Vol 42 (12) ◽  
pp. 1809-1814 ◽  
Author(s):  
Beverley B. Lazier ◽  
J. M. R. Beveridge

The enzymic activities of glucose-6-phosphate dehydrogenase, glutathione reductase, and catalase were studied in the red blood cells of male rats which were fed a basal diet designed to induce acute hepatic necrosis. Significant decreases in the activity were found for all three systems. These changes were prevented by supplementing the basal diet with one of the following: methionine, sodium selenite, DL-α-tocopherol acetate, or all three factors plus cystine.There was no significant change in 6-phosphogluconic dehydrogenase activity when it was investigated under similar circumstances.

Transfusion ◽  
2015 ◽  
Vol 56 (2) ◽  
pp. 427-432 ◽  
Author(s):  
Anna L. Peters ◽  
Robin van Bruggen ◽  
Dirk de Korte ◽  
Cornelis J.F. Van Noorden ◽  
Alexander P.J. Vlaar

Neonatology ◽  
2009 ◽  
Vol 96 (2) ◽  
pp. 96-101 ◽  
Author(s):  
Chun Hay Ko ◽  
Raymond Pui-On Wong ◽  
Pak Cheung Ng ◽  
Karen Li ◽  
Kit Man Chui ◽  
...  

Blood ◽  
1965 ◽  
Vol 25 (1) ◽  
pp. 92-95 ◽  
Author(s):  
IVO PANNACCIULLI ◽  
ALBERTO TIZIANELLO ◽  
FRANCO AJMAR ◽  
EMANUELE SALVIDIO

Abstract Two severe hemolytic crises, in a month’s period, were induced by primaquine in a glucose-6-phosphate dehydrogenase deficient Sardinian male. Young red blood cells tagged with Fe59 10 to 16 days earlier were destroyed in the second hemolytic episode. The implications of these experiments on the nature of drug-induced hemolysis in Caucasians are briefly discussed.


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