Article

1998 ◽  
Vol 76 (2) ◽  
pp. 137-141
Author(s):  
Sergey A Avilov ◽  
Olga A Drozdova ◽  
Vladimir I Kalinin ◽  
Anatoly I Kalinovsky ◽  
Valentin A Stonik ◽  
...  

Frondoside C (1) is a new sulfated nonholostane triterpene glycoside obtained (with the glycosides closed by aglycone structure as impurities) from the sea cucumber Cucumaria frondosa. Its structure has been elucidated on the basis of spectral data (NMR and MS) of compound 1 and of its desulfated derivative (2) obtained by solvolysis. Frondoside C (1) is just the seventh glycoside reported from sea cucumbers, having a lanostane-type aglycone devoid of the typical 18(20)- lactone ring.Key words: Cucumaria frondosa, sea cucumbers, frondosides, triterepene glycosides, antitumor activity.

2005 ◽  
Vol 83 (12) ◽  
pp. 2120-2126 ◽  
Author(s):  
Alexandra S Silchenko ◽  
Sergey A Avilov ◽  
Alexandr S Antonov ◽  
Anatoly I Kalinovsky ◽  
Pavel S Dmitrenok ◽  
...  

Frondosides A2-4 (1), A2-7 (2), and A2-8 (3) are new monosulfated triterpene glycosides isolated from the sea cucumber Cucumaria frondosa. Their structures have been elucidated on the basis of spectral data (2D NMR and MS). Frondosides A2-7 (2) and A2-8 (3) are isomers and differ from each other only by the position of a double bond in their non-holostane-type aglycones.Key words: Cucumaria frondosa, sea cucumbers, frondosides, triterpene glycosides.


2005 ◽  
Vol 83 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Alexandra S Silchenko ◽  
Sergey A Avilov ◽  
Alexandr S Antonov ◽  
Anatoly I Kalinovsky ◽  
Pavel S Dmitrenok ◽  
...  

Frondosides A2-1 (1), A2-2 (2), A2-3 (3), and A2-6 (4) are new monosulfated holostane pentaosides isolated from the sea cucumber Cucumaria frondosa. Their structures have been elucidated on the basis of spectral data (2D NMR and MS). Frondoside A2-2 (2) contains an α,β-unsaturated ketone fragment in the side chain of the aglycon, unique for triterpene glycosides of sea cucumbers.Key words: Cucumaria frondosa, sea cucumbers, frondosides, triterpene glycosides.


1998 ◽  
Vol 76 (2) ◽  
pp. 137-141 ◽  
Author(s):  
Sergey A. Avilov ◽  
Olga A. Drozdova ◽  
Vladimir I. Kalinin ◽  
Anatoly I. Kalinovsky ◽  
Valentin A. Stonik ◽  
...  

2011 ◽  
Vol 6 (8) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Alexandra S. Silchenko ◽  
Anatoly I. Kalinovsky ◽  
Sergey A. Avilov ◽  
Pelageya V. Andryjaschenko ◽  
Pavel S. Dmitrenok ◽  
...  

Four new triterpene glycosides cucumariosides H5 (1), H6 (2), H7 (3) and H8 (4) along with the known cucumarioside H (5) have been isolated from the Far Eastern sea cucumber Eupentacta fraudatrix. The structures of glycosides 1–4 were elucidated on the basis of spectral data (2D NMR and MS). Glycosides 1–4 belong to the group of cucumariosides H, having branched rare pentasaccharide carbohydrate moieties with one sulfate group and 3- O-methyl-D-xylose as a terminal monosaccharide unit. Glycosides 1–3 and 5 differ from each other in structures of side chains of the aglycones, while cucumarioside H8 (4) has a novel aglycone with unprecedented 16(22)-epoxy-group, never found in the sea cucumbers glycosides. Glycosides 1–3, and 5 were cytotoxic against mouse lymphocytes and hemolytic against mouse erythrocytes. Glycoside 2 was less active in comparison with others.


ChemInform ◽  
2010 ◽  
Vol 29 (40) ◽  
pp. no-no ◽  
Author(s):  
S. A. AVILOV ◽  
O. A. DROZDOVA ◽  
V. I. KALININ ◽  
A. I. KALINOVSKY ◽  
V. A. STONIK ◽  
...  

2019 ◽  
Vol 133 (2) ◽  
pp. 113 ◽  
Author(s):  
Emaline M. Montgomery ◽  
Tiffany Small ◽  
Jean-Francois Hamel ◽  
Annie Mercier

Orange-footed Sea Cucumber (Cucumaria frondosa; Echinodermata: Holothuroidea) is a dark-brown species that is broadly distributed in North Atlantic and Arctic waters. Here, we document the rare occurrence of colour morphs showing various degrees of albinism, from totally white to faint orange pigmentation. These unusually coloured individuals were found across a broad distribution range in eastern Canada and northeastern United States, with their occurrence in Newfoundland samples ranging from 0.2% to 0.5%. Two fully albino individuals were noticeably smaller than other colour morphs. The occurrence of rare, unusually coloured sea cucumbers is important from an ecological standpoint and may also have commercial implications.


1998 ◽  
Vol 76 (10) ◽  
pp. 1842-1849 ◽  
Author(s):  
Rabindra Singh ◽  
Bruce A MacDonald ◽  
Peter Lawton ◽  
Martin LH Thomas

Sea cucumbers (Cucumaria frondosa) (Echinodermata: Holothuroidea) held in flow-through tanks were exposed to different chloropigment concentrations by manipulating the seston concentration via the use of water filters in the inflow lines and the addition of cultured algae or natural plankton to tanks. The percentage of sea cucumbers open and feeding increased asymptotically as the seston chloropigment concentration increased. Below 50 µg·L-1 the percentage of sea cucumbers with tentacles extended and feeding decreased. The rate at which sea cucumbers inserted their tentacles into their mouths (0.96 ± 0.34 insertion/min (mean ± SD)) increased with increasing seston quality. Cucumaria frondosa fed at faster rates at the higher concentrations. There was a significant positive relationship between the stomach content (amount of chloropigment) of sea cucumbers and the seston chloropigment concentration to which they were exposed (r2 = 0.200, p < 0.001).


2007 ◽  
Vol 85 (9) ◽  
pp. 626-636 ◽  
Author(s):  
Alexandra S Silchenko ◽  
Sergey A Avilov ◽  
Anatoly I Kalinovsky ◽  
Pavel S Dmitrenok ◽  
Vladimir I Kalinin ◽  
...  

Seven highly polar trisulfated triterpene glycosides belonging to the frondoside A7 group have been isolated from the North Atlantic sea cucumber Cucumaria frondosa. The structures of five new glycosides, frondosides A7-1 (1), A7-2 (2), A7-3 (3), A7-4 (4), and isofrondoside C (5) were elucidated, three of which contained lanostane aglycons without a lactone-ring. Three pairs of the glycosides proved to be isomers by virture of the positions of double bonds in the aglycons nuclei; two pairs of the glycosides differed from each other by the character of the oxygen functionality at C-22. The results from these studies provided the basis for postulating the biosynthetic pathways of norlanostane glycosides in the sea cucumber.Key words: Cucumaria frondosa, sea cucumbers, frondosides, triterpene glycosides.


PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245238
Author(s):  
Catherine M. Couillard ◽  
Domynick Maltais ◽  
Rénald Belley

Sea cucumber Cucumaria frondosa have highly variable whole body mass and length, and are usually sold to Asian markets as dried gutted body wall. Understanding the relation between size and yield of dry product is essential for resource conservation and for economic purposes. In this study, stock-specific mass and length recovery rates were estimated for C. frondosa captured by dredging or diving at various depths and seasons on the South shore of the St. Lawrence Estuary, along Gaspé Peninsula, and processed in a commercial plant. The processing yield in dry product mass per sea cucumber was more than 1.5 times larger for sea cucumbers collected at 26–47 m depth compared to those collected at 9–16 m depth. Within each strata, there was little variation in the processed body mass, seasonally or spatially. Recovery rates based on gutted mass for this stock (13.4─14.5%) varied little among depths and seasons, despite observed seasonal and bathymetric variation in reproductive status. In contrast, recovery rates based on whole body mass and length were highly variable both seasonally and spatially. Stress related to dredging or post-capture handling induced important variable body contraction and water content, leading to variation in body length, mass and shape of sea cucumbers having the same processed body mass. Gutted mass was the best metric to predict processed body mass and to estimate size whereas whole body length was the least reliable. New stock-specific information on variability of body mass, length, and recovery rates induced by capture, and on seasonal and bathymetric variation in reproductive status and processing yields will be used for the design of future stock assessment surveys, and for stock conservation.


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