We discuss four methodological issues regarding cross-cultural judgment studies of facial expressions of emotion involving design, sampling, stimuli, and dependent variables. We use examples of relatively recent studies in this area to highlight and discuss these issues. We contend that careful consideration of these, and other, cross-cultural methodological issues can help researchers minimize methodological errors, and can guide the field to address new and different research questions that can continue to facilitate an evolution in the field’s thinking about the nature of culture, emotion, and facial expressions.