Letter to the Editor: Epilepsy in Chinese Culture

2001 ◽  
Vol 29 (01) ◽  
pp. 181-184 ◽  
Author(s):  
Tatia M. C. Lee ◽  
Serena H. C. Yang ◽  
Philip K.K. Ng
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Chinese Culture ◽  
Treatment Of Epilepsy ◽  
Letter To The Editor ◽  
Yin And Yang ◽  
Five Elements ◽  
Classification And Treatment

This article reviewed the meaning and development of epilepsy in Chinese culture. The theories of Yin and Yang and the five elements, fundamentals of traditional Chinese medicine, were introduced, which form the context of understanding of the etiology, classification, and treatment of epilepsy in traditional Chinese medicine.

Excavating Anticonvulsant Compounds from Prescriptions of Traditional Chinese Medicine in the Treatment of Epilepsy

2018 ◽  
Vol 46 (04) ◽  
pp. 707-737 ◽  
Author(s):  
Zefeng Zhao ◽  
Xirui He ◽  
Cuixia Ma ◽  
Shaoping Wu ◽  
Ye Cuan ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Therapeutic Strategy ◽  
In Vitro Models ◽  
New Drugs ◽  
Treatment Of Epilepsy ◽  
Effective Therapeutic Strategy ◽  
Promising Source

Traditional Chinese medicine (TCM) has a long history and been widely used in prevention and treatment of epilepsy in China. This paper is intended to review the advances in the active anticonvulsant compounds isolated from herbs in the prescription of TCM in the treatment of epilepsy. These compounds were introduced with the details including classification, CAS number specific structure and druggability data. Meanwhile, much of the research in these compounds in the last two decades has shown that they exhibited favorable pharmacological properties in treatment of epilepsy both in in vivo and in vitro models. In addition, in this present review, the evaluation of the effects of the anticonvulsant classical TCM prescriptions is discussed. According to these rewarding pharmacological effects and chemical substances, the prescription of TCM herbs could be an effective therapeutic strategy for epilepsy patients, and also could be a promising source for the development of new drugs.

scholarly journals Uncovering the Pharmacological Mechanism of Chaibei Zhixian Decoction on Epilepsy by Network Pharmacology Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Jian Zhang ◽  
Chenglong Zheng ◽  
Siyuan Yuan ◽  
Xiaoke Dong ◽  
Le Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Protein Kinase ◽  
Traditional Chinese Medicine ◽  
Protein Kinase B ◽  
Interleukin 1 ◽  
Negative Regulation ◽  
Network Pharmacology ◽  
Protein Targets ◽  
Treatment Of Epilepsy ◽  
Go Terms

Objective. Epilepsy is a neuronal disorder that is characterized by epileptic seizures and linked with abnormal neural functioning in the brain. Traditional Chinese medicine (TCM) formula Chaibei Zhixian decoction (CZD) has been widely used for epilepsy in China while the pharmacological mechanisms are still unclear. In the present study, systematic and comprehensive network pharmacology was utilized for the first time to reveal the potential pharmacological mechanisms of CZD on epilepsy. Methods. Traditional Chinese Medicine Systems Pharmacology (TCMSP) database and analysis platform was utilized for the development of an ingredients-targets database. After identifying epileptic targets of CZD, their interaction with other proteins was estimated based on protein-protein interaction network created from STITCH and gene ontology (GO) enrichment analysis utilizing Cytoscape-ClueGO plugin. Results. CZD formula was found to have 643 chemical ingredients, and the potential protein targets of these ingredients were 5230, as retrieved from TCMSP database. Twenty-six protein targets were found to be associated with epilepsy. Thirteen hub genes were regulated by CZD in epilepsy, including estradiol, ESR1, ESR2, SRC, CTNNB1, EP300, MAPK1, MAPK3, SP1, BRCA1, NCOA3, CHRM1, and GSK3B. The results of GO terms analysis showed that 8 GO terms were recovered in the form of 3 clusters, including negative regulation of protein kinase B signaling, positive regulation of interleukin-1 production, and microvillus assembly. Conclusions. Network pharmacology approach provides better understanding of the underlying pharmacological mechanisms of CZD on epilepsy. Estradiol, ESR1, ESR2, CTNNB1, EP300, MAPK1, MAPK3, BRCA1, and GSK3B are likely to be important molecules regulated by CZD in treatment of epilepsy. Negative regulation of protein kinase B signaling may play vital roles in the treatment of epilepsy by CZD.

scholarly journals Chakras’ Energies Alterations in Patients with Chronic Gastritis

2020 ◽  
Vol I (1) ◽  
pp. 20-23
Author(s):  
Huang Wei Ling
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Epigastric Pain ◽  
Case Reports ◽  
Chronic Fatigue ◽  
General Term ◽  
Auricular Acupuncture ◽  
Minimum Level ◽  
Dietary Counseling ◽  
Five Elements

Introduction Gastritis is a general term for inflammation of the stomach. In traditional Chinese medicine (TCM), gastritis is a disharmony between Yin, Yang, Qi, Blood and Heat retention of Liver, Stomach, Spleen or other disharmonies. Purpose To demonstrate that gastritis has energies alterations and chakras’ energies deficiencies as the root of its problem. The correction and replenishment of the chakras’ energies meridians are the most important goals in patient’s recovery. Methods Two case reports. The first, a 34-year-old male patient with complaints of chronic fatigue and epigastric pain, not improving with any medication the doctors prescribed. The second patient was a 32-year-old female who started having pain on the stomach and a burning sensation, as well as strong headache since she was 16-years-old. She was diagnosed with reflux through an endoscopy and treatment was started lansoprazole and pantoprazole and diet for reflux. She performed this treatment for four years, with no success. Both patients did the chakras’ energies meridian measurement through radiesthesia procedure. The result was that six out of seven chakras’ were completely lack of energies rated one (the minimum level) out of eight (the normal level), with the exception of the seventh chakra that was normal. Both patients were treated with Chinese dietary counseling, auricular acupuncture with apex ear bloodletting, systemic acupuncture and replenishment of the chakras’ energies with homeopathic medication according to Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine and crystal based medications. Results Both patients recover from all their symptoms very fast, including the epygastric pain discomfort without the necessity of using any antacid and proton-pump inhibitors medications. Conclusion Gastritis has an energy alteration and chakras’ energies deficiencies as a root and the treatment of these energy imbalances and replenishment of this lack of energies is essential for the patient’s improvement in the deepest level, not only treating the symptom. Keywords: Gastritis; Energy; Chakra; Traditional Chinese Medicine; Homeopathy; Crystal-based medication.

scholarly journals Recognizing Traditional Chinese Medicine Customs during the COVID-19 Pandemic: A Case Report

2021 ◽  
pp. 239
Author(s):  
◽  
◽  
◽  
◽  
Keyword(s):  
Case Report ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Healthcare Providers ◽  
The Body ◽  
Alternative Health ◽  
Competency Training ◽  
Cultural Competency Training ◽  
Physical Barriers ◽  
Yin And Yang

Traditional Chinese Medicine (TCM) is based on the belief of vital energy (qi) within the body and attributes disease with imbalance in energies (yin and yang). The COVID-19 pandemic has necessitated unique physical barriers, including increased physical distancing, use of personal protective equipment (PPE), and telehealth services, which complicate existing efforts to understand alternative health practices. This case report highlights the importance of cultural competency training for healthcare providers, as evident in improved patient care when recognizing and acknowledging TCM customs in association with the COVID-19 pandemic.

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