NOVEL METHOD FOR ASSESSING ARTERIAL STIFFNESS BASED ON OSCILLOMETRIC BLOOD PRESSURE MEASUREMENT

2018 ◽  
Vol 18 (07) ◽  
pp. 1840010
Author(s):  
CHI ZHANG ◽  
YONGJIA GAO ◽  
TAOCHEN LONG ◽  
YI DU ◽  
XIAOXU HOU ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Brachial Artery ◽  
Mechanical Characteristics ◽  
Pulse Wave ◽  
Arterial Compliance ◽  
Blood Pressure Measurement ◽  
Physiological Significance ◽  
Novel Method ◽  
Oscillometric Blood Pressure Measurement

Arterial stiffness is a major contributor to cardiovascular diseases. The aim of this study is to explore the physiological significance of the brachial mechanical parameters, which could be estimated from oscillometric blood pressure (BP) measurement, and investigate on the potential of these arterial parameters as an index of arterial stiffness. The mechanical characteristics of brachial artery were modeled based on the collapsible tube theory, which includes two important parameters to describe the compliance of brachial artery. After the model validation, the arterial parameters were estimated from the measured oscillometric envelope of 56 subjects by solving an inverse problem. The physiological significance of these parameters was explored by analyzing their association with pulse wave velocity (PWV) as well as with the BP. Arterial compliance parameters were successfully estimated from the envelope of the oscillometric pulse wave in the BP measurement. The parameters were found to be linearly associated with age, PWV, and BP. These results suggest that our method may provide a potential approach to assess arterial compliance based on oscillometric measurement of BP.

PS 05-73 THE DEGREE OF CHANGES IN BLOOD PRESSURE AFTER RE-FLOW OF BRACHIAL ARTERY DURING BLOOD PRESSURE MEASUREMENT MIGHT BE PREDICT ARTERIAL STIFFNESS

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e161
Author(s):  
Byong-kyu Kim ◽  
Yon Woong Park ◽  
Seung Pyo Hong ◽  
Young Soo Lee ◽  
Jin Bae Lee ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Brachial Artery ◽  
Pressure Measurement ◽  
Blood Pressure Measurement

scholarly journals Impact of blood pressure perturbations on arterial stiffness

2015 ◽  
Vol 309 (12) ◽  
pp. R1540-R1545 ◽  
Author(s):  
Jisok Lim ◽  
Miriam E. Pearman ◽  
Wonil Park ◽  
Mohammed Alkatan ◽  
Daniel R. Machin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Elastic Modulus ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Young’S Modulus ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Arterial Compliance ◽  
Stiffness Index ◽  
Arterial Distensibility

Although the associations between chronic levels of arterial stiffness and blood pressure (BP) have been fairly well studied, it is not clear whether and how much arterial stiffness is influenced by acute perturbations in BP. The primary aim of this study was to determine magnitudes of BP dependence of various measures of arterial stiffness during acute BP perturbation maneuvers. Fifty apparently healthy subjects, including 25 young (20–40 yr) and 25 older adults (60–80 yr), were studied. A variety of BP perturbations, including head-up tilt, head-down tilt, mental stress, isometric handgrip exercise, and cold pressor test, were used to encompass BP changes induced by physical, mental, and/or mechanical stimuli. When each index of arterial stiffness was plotted with mean BP, all arterial stiffness indices, including cardio-ankle vascular index or CAVI ( r = 0.50), carotid-femoral pulse wave velocity or cfPWV ( r = 0.51), brachial-ankle pulse wave velocity or baPWV ( r = 0.61), arterial compliance ( r = −0.42), elastic modulus ( r = 0.52), arterial distensibility ( r = −0.32), β-stiffness index ( r = 0.19), and Young's modulus ( r = 0.35) were related to mean BP (all P < 0.01). Changes in CAVI, cfPWV, baPWV, and elastic modulus were significantly associated with changes in mean BP in the pooled conditions, while changes in arterial compliance, arterial distensibility, β-stiffness index, and Young's modulus were not. In conclusion, this study demonstrated that BP changes in response to various forms of pressor stimuli were associated with the corresponding changes in arterial stiffness indices and that the strengths of associations with BP varied widely depending on what arterial stiffness indices were examined.

Oscillometric Determination of Diastolic, Mean and Systolic Blood Pressure—A Numerical Model

1986 ◽  
Vol 108 (4) ◽  
pp. 359-364 ◽  
Author(s):  
F. K. Forster ◽  
D. Turney
Keyword(s):  
Blood Pressure ◽  
Diastolic Pressure ◽  
Cuff Pressure ◽  
Arterial Compliance ◽  
Blood Pressure Measurement ◽  
Pressure Curve ◽  
Pressure Waveform ◽  
Blood Pressure Waveform ◽  
Collapse Behavior ◽  
Oscillometric Blood Pressure Measurement

A theoretical model of oscillometric blood pressure measurement is presented. Particular emphasis is paid to the collapse behavior of the artery, and an exponential volume-pressure curve is used. The results of this study suggest that mean blood pressure can be accurately predicted from the peak of the oscillometric curve if corrections related to the cuff pressure waveform are applied. It is also shown, however, that systolic and diastolic pressure may not in general be accurately determined from fixed amplitude ratios based on the oscillometric peak due to the sensitivity of the method to variations in blood pressure waveform, pulse pressure, and arterial compliance. No simple procedures are found to correct for these effects.

Abstract 3077: Cross-Sectional Associations of Arterial Stiffness Measures and Ankle-Brachial Index: The Multi-Ethnic Study of Atherosclerosis (MESA)

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
John T Wilkins ◽  
Mary M McDermott ◽  
Kiang Liu ◽  
Cheeling Chan ◽  
Michael Criqui ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Mechanical Characteristics ◽  
Pulse Wave ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
Cross Sectional ◽  
Men And Women ◽  
Independent Variables ◽  
Vascular Impedance ◽  
Peripheral Arterial

The association between tonometry-derived measures of arterial stiffness and peripheral arterial disease (PAD) is unclear. Using baseline data from 2847 female and 2614 male participants of the NHLBI-funded MESA study, we conducted linear regression analyses adjusted for age, demographics and risk factors. Ankle-brachial index (ABI) was the dependent variable and measures of large (C1) and small artery elasticity (C2) and total vascular impedance (TVI), all measured from radial artery tonometry, were the independent variables in separate models. In men and women, lower C1 and C2 values were associated with lower ABI. Higher TVI was associated with lower ABI in men and women [P<0.001]. Significant trends for C1, C2 and TVI were observed across clinical strata of ABI (Table ). In pairwise analyses, compared with participants with a normal ABI (1.1 to <1.3), those with ABI <1.1 tended to have significantly lower C2. Additionally, women with high ABI (1.3–1.5) tended to have significantly higher C2 values. Pairwise comparisons of lower and higher ABI groups compared with normal groups did not yield consistent findings for C1. Significantly higher TVI levels with lower ABI group were noted mostly in women (Table ). We observed a continuum of arterial mechanical characteristics across clinical ABI values, indicating that measures of arterial stiffness are significantly associated with ABI and severity of PAD. These results suggest that changes in C2 occur in patients with advanced lower extremity large-vessel atherosclerotic disease. Of note, female participants with high ABI between 1.3–1.5 had a significantly higher C2, arguing against the accepted “non-compressible” or “calcified arterial disease” explanation for high ABI in women. Associations Between ABI and Pulse Wave Analysis Measurements when adjusted for age, cigarette smoking, diabetes, hypertension, and creatinine level

Arterial Stiffness, Pulse Wave Analyses: What Can't Blood Pressure Tell you in Chronic Kidney Disease

2012 ◽  
Vol 8 (4) ◽  
pp. 244-249
Author(s):  
Antonio Bellasi ◽  
Paolo Salvi ◽  
Sergio Papagni ◽  
Emiliana Ferramosca ◽  
Carlo Ratti ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Arterial Stiffness ◽  
Pulse Wave

scholarly journals The Emergence of Ambulatory Measurement of Arterial Stiffness and Central Blood Pressure. A Promising Novelty of Clinical Importance or Just Another Marker?

2013 ◽  
Vol 5 (1) ◽  
pp. 82-86
Author(s):  
A. Lazaridis ◽  
E. Gkaliagkousi ◽  
M. Doumas ◽  
A. Reklou ◽  
A. Karagiannis
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Arterial Stiffness ◽  
Integrated Assessment ◽  
Pulse Wave ◽  
Clinical Importance ◽  
Organ Damage ◽  
Brachial Blood Pressure ◽  
Ambulatory Measurement ◽  
The Everyday

Whereas brachial blood pressure (BP) is still considered the gold standard for the estimation of cardiovascular risk in all clinical trials and guidelines, scientific interest is shifting towards central hemodynamics and the scientific community is experiencing a whole new revolution with the emergence of novel cardiovascular markers such as the ambulatory measurement of central BP and arterial stiffness. Central BP has already started to demonstrate its superiority over peripheral BP as a better and more reliable predictor of end-organ damage in cardiovascular diseases. Furthermore, ambulatory measurement of central BP and pulse wave velocity are expected to add much more useful information towards a more integrated assessment of cardiovascular risk and profile. However, more research is required before these novel markers could be incorporated in the everyday practice of BP measurement.

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