Real-time flow-rate control system for cell analysis

Author(s):  
Tadayoshi Aoyama ◽  
Amalka De Zoysa ◽  
Qingyi Gu ◽  
Takeshi Takaki ◽  
Idaku Ishii
2016 ◽  
Vol 28 (6) ◽  
pp. 854-861 ◽  
Author(s):  
Tadayoshi Aoyama ◽  
◽  
Amalka De Zoysa ◽  
Qingyi Gu ◽  
Takeshi Takaki ◽  
...  

[abstFig src='/00280006/09.jpg' width='300' text='Snapshots of particle sorting experiment using our system' ] On-chip cell analysis is an important issue for microtechnology research, and microfluidic devices are frequently used in on-chip cell analysis systems. One approach to controlling the fluid flow in microfluidic devices for cell analysis is to use a suitable pumps. However, it is difficult to control the actual flow-rate in a microfluidic device because of the difficulty in placing flow-rate sensors in the device. In this study, we developed a real-time flow-rate control system that uses syringe pumps and high-speed vision to measure the actual fluid flow in microfluidic devices. The developed flow-rate control system was verified through experiments on microparticle velocity control and microparticle sorting.


2015 ◽  
Vol 2015 (0) ◽  
pp. _1P1-M03_1-_1P1-M03_2
Author(s):  
Tadayoshi AOYAMA ◽  
Zoysa Amalka ◽  
Qingyi GU ◽  
Takeshi TAKAKI ◽  
Idaku ISHII

Author(s):  
E. G. Berestovitskiy ◽  
P. I. Kizilov ◽  
A. N. Kruchkov ◽  
N. V. Pialov

2019 ◽  
Vol 9 (10) ◽  
pp. 1978
Author(s):  
Yoshiyuki Noda ◽  
Yuta Sueki

In this paper, we study an advanced pouring control system using a tilting-ladle-type automatic pouring machine. In such a machine, it is difficult to precisely pour the molten metal into the pouring basin of the mold, as the outflow from the ladle can be indirectly controlled by controlling its tilt. Therefore, model-based pouring control systems have been developed as a part of conventional studies to solve this problem. In the results of a recent study, the efficacy of a pouring flow rate control system based on differential flatness has been verified, by performing a simulation. In this study, we apply the flow rate control system based on differential flatness to a tilting-ladle-type automatic pouring machine, using experiments to verify the efficacy of the flow rate control system in suppressing any disturbances. In these experiments, the tracking performance using the developed flow rate control system was better than the performance obtained using a conventional feed-forward-type flow rate control system.


Metallurgist ◽  
1984 ◽  
Vol 28 (10) ◽  
pp. 335-336
Author(s):  
S. L. Solomentsev ◽  
B. L. Markov ◽  
V. K. Sigmund ◽  
S. M. Basukinskii ◽  
A. P. Pukhov ◽  
...  

2007 ◽  
Vol 19 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Yoshiyuki Noda ◽  
◽  
Kazuhiko Terashima

This paper concerns control of the pouring process of tilting-ladle-type automatic pouring systems used in the casting industry. Here, the flow rate is modeled mathematically using mass equilibrium and Bernoulli’s theorem, then a feedforward flow rate control system is constructed by using the flow rate model’s inverse dynamics. The proposed control system can improve the accuracy of the flow rate, and enables flow rate control to be designed systematically for the various types of ladles used in casting plants. In order to verify the effectiveness of the proposed control system, the system was applied to an automatic pouring system which was tested experimentally using both water and molten metal.


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