With the edge of the application and key technologies, the management ideas that are the integration of equipment development and production stage of technology status management put forward and combed this project, providing comprehensive data management environment, providing rapid decision-making, timely information and scientific basis
AbstractNucleosome organization is involved in many regulatory activities in various organisms. However, studies integrating nucleosome organizations in mammalian genomes are very limited mainly due to the lack of comprehensive data management. Here, we presentNUCOME, which is the first database to organize publicly available MNase-seq data resource and manage unified processed datasets covering various cell types in human and mouse. TheNUCOMEprovides standard, qualified and informative nucleosome organization data at the genome scale and at any genomic regions for users’ downstream analyses.NUCOMEis freely available athttp://compbio.tongji.edu.cn/NUCOME/.
NUCOME: A Comprehensive Database of Nucleosome Organizations in Mammalian Genomes