Understanding Age-Related Changes in Skeletal Muscle Metabolism: Differences Between Females and Males

2016 ◽  
Vol 36 (1) ◽  
pp. 129-156 ◽  
Author(s):  
Brandon J.F. Gheller ◽  
Emily S. Riddle ◽  
Melinda R. Lem ◽  
Anna E. Thalacker-Mercer
1994 ◽  
Vol 30 (2) ◽  
pp. 171-185 ◽  
Author(s):  
O. Pastoris ◽  
M. Dossena ◽  
R. Arnaboldi ◽  
A. Gorini ◽  
R.F. Villa

2020 ◽  
Vol 21 (2) ◽  
pp. 592 ◽  
Author(s):  
Elena Rezuş ◽  
Alexandra Burlui ◽  
Anca Cardoneanu ◽  
Ciprian Rezuş ◽  
Cătălin Codreanu ◽  
...  

Aging is an inevitable and gradually progressive process affecting all organs and systems. The musculoskeletal system makes no exception, elderly exhibit an increased risk of sarcopenia (low muscle mass),dynapenia (declining muscle strength), and subsequent disability. Whereas in recent years the subject of skeletal muscle metabolic decline in the elderly has been gathering interest amongst researchers, as well as medical professionals, there are many challenges yet to be solved in order to counteract the effects of aging on muscle function efficiently. Noteworthy, it has been shown that aging individuals exhibit a decline in skeletal muscle metabolism, a phenomenon which may be linked to a number of predisposing (risk) factors such as telomere attrition, epigenetic changes, mitochondrial dysfunction, sedentary behavior (leading to body composition alterations), age-related low-grade systemic inflammation (inflammaging), hormonal imbalance, as well as a hypoproteic diet (unable to counterbalance the repercussions of the age-related increase in skeletal muscle catabolism). The present review aims to discuss the relationship between old age and muscle wasting in an effort to highlight the modifications in skeletal muscle metabolism associated with aging and physical activity.


2004 ◽  
Vol 39 (2) ◽  
pp. 203-210 ◽  
Author(s):  
Laurent Mosoni ◽  
Denis Breuillé ◽  
Caroline Buffière ◽  
Christiane Obled ◽  
Philippe Patureau Mirand

Diabetes ◽  
2016 ◽  
Vol 66 (2) ◽  
pp. 560.2-560
Author(s):  
Blake J. Cochran ◽  
Liming Hou ◽  
Anil Paul Chirackal Manavalan ◽  
Benjamin M. Moore ◽  
Fatiha Tabet ◽  
...  

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