Late adverse reactions to nonionic contrast media.

Radiology ◽  
1992 ◽  
Vol 183 (3) ◽  
pp. 737-740 ◽  
Author(s):  
H Yoshikawa
2012 ◽  
Vol 24 (1) ◽  
pp. 22 ◽  
Author(s):  
Kyung Eun Jung ◽  
Jimin Chung ◽  
Byung Cheol Park ◽  
Keum Nahn Jee ◽  
Young Koo Jee ◽  
...  

1994 ◽  
Vol 162 (3) ◽  
pp. 523-526 ◽  
Author(s):  
E C Lasser ◽  
C C Berry ◽  
M M Mishkin ◽  
B Williamson ◽  
N Zheutlin ◽  
...  

1995 ◽  
Vol 36 (1) ◽  
pp. 72-76 ◽  
Author(s):  
R. Mikkonen ◽  
T. Kontkanen ◽  
L. Kivisaari

A prospective study of acute and late reactions to low-osmolal contrast media was conducted in 4 875 patients. The contrast medium was injected intravenously in 4 417 patients and intraarterially in 458 for CT, urography or angiography. In the i.v. group only nonionic contrast media, iohexol or iopamidol, were used and in the intraarterial group both ionic and nonionic contrast media, ioxaglate and iohexol, were used. The patients completed 2-phase questionnaires, the rate of reply being 88%. In the i.v. group the incidence of acute reactions was 1.2% and that of late reactions was 4.7%. In the intraarterial group the incidence of acute reactions was 7.4% and the incidence of late reactions was 4.8%. Women and patients from under 40 to 60 years of age were the most susceptible to late reactions. The risk factors for late reactions are allergy, medicine allergy, previous adverse reaction to contrast medium and other diseases including diabetes mellitus, heart-, liver- and kidney diseases.


Radiology ◽  
1990 ◽  
Vol 175 (3) ◽  
pp. 621-628 ◽  
Author(s):  
H Katayama ◽  
K Yamaguchi ◽  
T Kozuka ◽  
T Takashima ◽  
P Seez ◽  
...  

2019 ◽  
Vol 14 (2) ◽  
pp. 122-126
Author(s):  
Deepti Chopra ◽  
Abhinav Jain ◽  
Richa Garg ◽  
Shreya Dhingra

Background: Radiocontrast media are used extensively nowadays to visualize internal organs. Currently, non-ionic iodinated contrast media are used which are generally considered to be safe but some adverse reactions have been reported. Thus, the present study was carried out to analyze the nature and incidence of adverse drug reactions (ADRs) to radiographic contrast media in a teaching hospital. Methods:An observational study carried out for a period of six months in a teaching hospital. Contrast media induced adverse reactions were analyzed in terms of affected organs, rate, causality assessment, severity and preventability. The treatment and outcomes of adverse events were also recorded. Naranjo Probability Scale was used to evaluate the relationship between the contrast agent used and the suspected ADR. The severity of the suspected ADRs was determined using Hartwig Scale and preventability was assessed using modified Schumock and Thornton criterion. Results:A total of 15 suspected ADRs occurred in 11 patients with an incidence of 1.4%. It included 5 (45.4%) males and 6 (54.5%) females (p < 05). The highest percentage (72.7 %) of ADRs was seen in adult patients, the mean age being 40.8 years. Vomiting (33.3%) was the most common ADR noted followed by severe nausea and rashes. 64.7 % of ADRs were categorized as probable and 35.3 % were possible. Adverse reactions required treatment in 46.6% patients. There was no fatality reported. Conclusion:The reactions observed were mild to moderate in severity and occurred within 30 minutes of the administration of the contrast.


1991 ◽  
Vol 156 (4) ◽  
pp. 865-866 ◽  
Author(s):  
E Kotlyarov ◽  
G S Johnston ◽  
S Mirvis

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