The life and death of laboratory teaching of medical physiology: a personal narrative. Part I.

1993 ◽  
Vol 264 (6) ◽  
pp. S16 ◽  
Author(s):  
H W Davenport

Part I of this essay sketches the history of laboratory teaching of medical physiology in England from the perspective of the author as a student at Oxford from 1935 to 1938. The systematic laboratory teaching that began in the 1870s at University College London under William Sharpey was carried to Oxford, as well as to other English and Scottish universities, by Sharpey's junior colleagues. C. S. Sherrington added mammalian experiments, and C. G. Douglas and J. G. Priestley added experiments on human subjects. The author describes his experience as a student in the Oxford courses and tells how he learned physiology by teaching it from 1941 to 1943 in the laboratory course established at the University of Pennsylvania by Oxford-trained physiologist Cuthbert Bazett.

1993 ◽  
Vol 265 (6) ◽  
pp. S55 ◽  
Author(s):  
H W Davenport

Part II of this essay describes the author's participation in the laboratory course instituted by Eugene Landis at Harvard in 1943, a course that drew heavily on Thomas Lewis's example. He describes in detail his own methods of laboratory teaching at Utah and Michigan when, as department chair, he had the responsibility for organizing courses in physiology for medical students. In conclusion, the author laments the curtailment and eventual abolition of laboratory teaching in the 1970s that resulted from curriculum reform, student revolt, and faculty indifference.


1953 ◽  
Vol 22 (66) ◽  
pp. 97-97
Author(s):  
T. B. L. Webster

The Classical Association was founded in December 1903 in the Botany Lecture Theatre of University College, London. University College has invited the Association to celebrate its Jubilee there from 7 to 10 April 1954. Invitations have been received from the University, King's College, and Westminster School to hold part of the functions in their buildings and a special exhibition of new books is being arranged by the University Library. In connexion with the Jubilee an appeal is being issued to members with the object of raising a small working capital to avoid the necessity of increasing the subscription, which in spite of growing membership no longer produces enough to cover the increased cost of printing and provides no margin for extra activities.It is hoped that the Hon. Secretary, Professor L. J. D. Richardson, will give the opening lecture on the history of the Association. Headings will clearly be: the foundation of local branches in this country and of parallel associations in the Commonwealth, the establishment of the Association's three journals, the institution of school reading competitions, and the excellent work done by the Education Sub-Committee. During its fifty years of life the Association has endeavoured to fulfil the objects laid down in the rules. Two recent activities are designed particularly ‘to encourage investigation and call attention to new discoveries’ and ‘to create opportunities for friendly intercourse’, viz. participation in the Joint Committee of Greek and Roman Societies, which runs the successful triennial meetings at Oxford and Cambridge, and membership of the International Federation of Classical Studies, whose next conference will be in Copenhagen in August 1954.


1942 ◽  
Vol 13 (4) ◽  
pp. 438
Author(s):  
Robert E. Spiller ◽  
Edward Potts Cheyney ◽  
Cornell M. Dowlin ◽  
Agnes Addison

Author(s):  
Vincent W. Hevern ◽  
Elizabeth R. Valentine ◽  
Bernard Spilka ◽  
Horst Gundlach ◽  
Roger K. Thomas ◽  
...  

Author(s):  
Douglass F. Taber

Benjamin List of the Max-Planck-Institut, Mülheim, devised (J. Am. Chem. Soc. 2010, 132, 10227) a catalyst system for the stereocontrolled epoxidation of a trisubstituted alkenyl aldehyde 1. Takashi Ooi of Nagoya University effected (Angew. Chem. Int. Ed. 2010, 49, 7562; see also Org. Lett. 2010, 12, 4070) enantioselective Henry addition to an alkynyl aldehyde 3. Madeleine M. Joullié of the University of Pennsylvania showed (Org. Lett. 2010, 12, 4244) that an amine 7 added selectively to an alkynyl aziridine 6. Yutaka Ukaji and Katsuhiko Inomata of Kanazawa University developed (Chem. Lett. 2010, 39, 1036) the enantioselective dipolar cycloaddition of 9 with 10. K. C. Nicolaou of Scripps/La Jolla observed (Angew. Chem. Int. Ed. 2010, 49, 5875; see also J. Org. Chem. 2010, 75, 8658) that the allylic alcohol from enantioselective reduction of 12 could be hydrogenated with high diastereocontrol. Masamichi Ogasawara and Tamotsu Takahashi of Hokkaido University added (Org. Lett. 2010, 12, 5736) the allene 14 to the acetal 15 with substantial stereocontrol. Helen C. Hailes of University College London investigated (Chem. Comm. 2010, 46, 7608) the enzyme-mediated addition of 18 to racemic 17. Dawei Ma of the Shanghai Institute of Organic Chemistry, in the course of a synthesis of oseltamivir (Tamiflu), accomplished (Angew. Chem. Int. Ed. 2010, 49, 4656) the enantioselective addition of 21 to 20. Shigeki Matsunaga of the University of Tokyo and Masakatsu Shibasaki of the Institute of Microbial Chemistry developed (Org. Lett. 2010, 12, 3246) a Ni catalyst for the enantioselective addition of 23 to 24. Juthanat Kaeobamrung and Jeffrey W. Bode of ETH-Zurich and Marisa C. Kozlowski of the University of Pennsylvania devised (Proc. Natl. Acad. Sci. 2010, 107, 20661) an organocatalyst for the enantioselective addition of 27 to 26. Yihua Zhang of China Pharmaceutical University and Professor Ma effected (Tetrahedron Lett. 2010, 51, 3827) the related addition of 27 to 29. There have been scattered reports on the stereochemical course of the coupling of cyclic secondary organometallics. In a detailed study, Paul Knochel of Ludwig-Maximilians- Universität München showed (Nat. Chem. 2020, 2, 125) that equatorial bond formation dominated, exemplified by the conversion of 31 to 33.


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