Fetal fuels. III: Ketone utilization by fetal hepatocyte.

1978 ◽  
Vol 235 (3) ◽  
pp. E330 ◽  
Author(s):  
G E Shambaugh ◽  
R R Koehler ◽  
H Yokoo
Keyword(s):  
1994 ◽  
Vol 160 (3) ◽  
pp. 445-454 ◽  
Author(s):  
Masanobu Nanno ◽  
Masahiro Hata ◽  
Hideki Yagi ◽  
Tsunetoshi Itoh ◽  
Hideyuki Doi ◽  
...  

1984 ◽  
Vol 105 (1) ◽  
pp. 211-220 ◽  
Author(s):  
Christiane Guguen-Guillouzo ◽  
Bruno Clement ◽  
Gérard Lescoat ◽  
Denise Glaise ◽  
André Guillouzo

2010 ◽  
Vol 90 ◽  
pp. 464
Author(s):  
M. G. Joshi ◽  
P. B. Patil ◽  
N. Hernandez ◽  
D. Hallberg ◽  
Z. He ◽  
...  
Keyword(s):  

Antioxidants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1059
Author(s):  
Marianna Pauletto ◽  
Mery Giantin ◽  
Roberta Tolosi ◽  
Irene Bassan ◽  
Andrea Barbarossa ◽  
...  

Aflatoxin B1 (AFB1) toxicity in livestock and human beings is a major economic and health concern. Natural polyphenolic substances with antioxidant properties have proven to be effective in ameliorating AFB1-induced toxicity. Here we assessed the potential anti-AFB1 activity of curcumin (pure curcumin, C, and curcumin from Curcuma longa, CL) in a bovine fetal hepatocyte-derived cell line (BFH12). First, we measured viability of cells exposed to AFB1 in presence or absence of curcumin treatment. Then, we explored all the transcriptional changes occurring in AFB1-exposed cells cotreated with curcumin. Results demonstrated that curcumin is effective in reducing AFB1-induced toxicity, decreasing cells mortality by approximately 30%. C and CL induced similar transcriptional changes in BFH12 exposed to AFB1, yet C treatment resulted in a larger number of significant genes compared to CL. The mitigating effects of curcuminoids towards AFB1 toxicity were mainly related to molecular pathways associated with antioxidant and anti-inflammatory response, cancer, and drug metabolism. Investigating mRNA changes induced by curcumin in cattle BFH12 cells exposed to AFB1 will help us to better characterize possible tools to reduce its consequences in this susceptible and economically important food-producing species.


1987 ◽  
Vol 492 (1 Alcohol and t) ◽  
pp. 224-232 ◽  
Author(s):  
GEORGE I. HENDERSON ◽  
DAVID W. HEITMAN ◽  
STEVEN SCHENKER
Keyword(s):  

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