THE RELATIONSHIP OF CHANGES IN BLOOD-FLOW THROUGH AN EXTREMITY TO (1) CHANGES IN TEMPERATURE OF TISSUES, (2) DIFFERENCES IN OXYGEN CONTENT OF THE ARTERIAL AND VENOUS BLOOD, AND (3) CARDIAC OUTPUT

1929 ◽  
Vol 91 (1) ◽  
pp. 115-122 ◽  
Author(s):  
Hubert B. Bradburn ◽  
Alfred Blalock
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Oxygen Content ◽  
Venous Blood ◽  
Flow Through ◽  
Relationship Of ◽  
The Relationship

Effects of epinephrine on cardiovascular and metabolic responses to leg exercise in man

1963 ◽  
Vol 18 (6) ◽  
pp. 1118-1122 ◽  
Author(s):  
Robert J. Marshall ◽  
John T. Shepherd
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Oxygen Content ◽  
Muscle Blood Flow ◽  
Venous Blood ◽  
Metabolic Responses ◽  
Leg Muscles ◽  
Leg Exercise ◽  
The Subject ◽  
The Mean

In studies on six experienced subjects lying supine, cardiac output and oxygen content of femoral venous blood were measured with the subject at rest, during the increase in muscle blood flow caused by intravenous infusion of epinephrine, during mild leg exercise, and during identical exercise combined with an infusion. The oxygen content of the blood from the exercising limb was much higher (average, 50%) during an infusion than when no infusion was given (average, 32%). The mean increase in cardiac output during the combined maneuver (8.2 liters/min) almost equaled the sum of the increases during the separate infusion (3.7 liters) and during exercise (4.7 liters). All individual studies showed approximately this same result. Thus, the additional blood supplied to the leg muscles by the infusion did not appear to be used for metabolic purposes during exercise. cardiac output; muscle blood flow Submitted on March 22, 1963

Relationship of blood flow to pressure in the intestinal vascular bed of the dog

1962 ◽  
Vol 202 (2) ◽  
pp. 253-256 ◽  
Author(s):  
E. Clinton Texter ◽  
Steven Merrill ◽  
Melvin Schwartz ◽  
Guido Van Derstappen ◽  
Francis J. Haddy
Keyword(s):  
Blood Flow ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Vascular Bed ◽  
Local Mechanism ◽  
Small Vein ◽  
Flow Through ◽  
Renal Vascular ◽  
Relationship Of ◽  
The Relationship

The relationship of pressure in the superior mesenteric artery, mesenteric small artery, mesenteric small vein, and portal vein to the rate of blood flow in the superior mesenteric artery was studied in eight dogs. Total bed resistance to blood flow decreased as a function of flow over the range 20–60 ml/min but increased as a function of flow over the range 90–270 ml/min. The onset and cessation of the resistance increase were associated with pressures in the superior mesenteric artery of 64 and 205 mm Hg, respectively. These resistance changes resulted mainly from change of resistance to flow through vessels less than 0.5 mm diameter. The findings suggest that the intestinal vascular bed, like the renal vascular bed, has a local mechanism which antagonizes changes of flow rate produced by variation of arterial pressure.

Effect of two methods of hand heating on body temperature, forearm blood flow, and deep venous oxygen saturation

1990 ◽  
Vol 259 (5) ◽  
pp. E639-E643 ◽  
Author(s):  
I. W. Gallen ◽  
I. A. Macdonald
Keyword(s):  
Blood Flow ◽  
Body Temperature ◽  
Oxygen Content ◽  
Forearm Blood Flow ◽  
Venous Blood ◽  
Blood Oxygen ◽  
Left Hand ◽  
Venous Oxygen Saturation ◽  
Baseline Values ◽  
Healthy Females

Two methods of hand heating [warmed blanket 40 degrees C (WB) and warm-air box 55 degrees C (WA)] were compared with the effect of no heating (control) in six healthy females. After 30 min baseline, the left hand was either heated for 1 h or not heated. Measurements were made of skin temperature (ST), core temperature (CT), right forearm (FBF) and skin blood flow (SBF), and right forearm deep venous blood oxygen content with and without occlusion of the hand circulation. CT rose above baseline in WB (by +0.2 degrees C, P less than 0.01) but not with control or WA. Abdominal ST rose only with WB (by +0.66 degrees C above baseline, P less than 0.01). FBF increased above baseline values with both WA (by +10 ml.l forearm-1.min-1) and WB (by +12 ml.l forearm-1.min-1), but neither was significantly greater than the control. SBF increased above baseline only with WB (by +202 mV, P less than 0.01), and this was significantly greater than control SBF. With an occluded hand circulation, deep venous oxygen content rose above baseline values with WB only (+6.0%, P less than 0.01) but was not greater than control with either method of hand heating. We conclude that using a warm-air box has less effect than a heated blanket on the measured variables.

Relation of blood flow to VO2, PO2, and PCO2 in dog gastrocnemius muscle

1988 ◽  
Vol 255 (5) ◽  
pp. H1004-H1010 ◽  
Author(s):  
D. E. Mohrman ◽  
R. R. Regal
Keyword(s):  
Blood Flow ◽  
Steady State ◽  
Gastrocnemius Muscle ◽  
Muscle Blood Flow ◽  
Carbon Dioxide Tension ◽  
Experimental Conditions ◽  
Muscle Oxygen ◽  
Muscle Oxygen Consumption ◽  
Relationship Of ◽  
The Relationship

We pump-perfused gastrocnemius-plantaris muscle preparations at constant pressure to study the relationship of muscle blood flow (Q) to muscle oxygen consumption (VO2), venous oxygen tension (PVO2), and venous carbon dioxide tension (PVCO2) during steady-state exercise at different rates. Tests were performed under four experimental conditions produced by altering the perfusate blood-gas status with a membrane lung. The consistency of the relationship of Q to other variables was evaluated by statistical analysis of fitted curves. Not one of the above listed variables had the same relationship with Q in all four of the experimental conditions we tested. However, we did find that a consistent relationship existed among Q, PVO2, and PVCO2 in our data. That relationship is well described by the equation (Q-23).[PVO2 - (0.5.PVCO2) - 3] = 105 (when Q is expressed in ml.100 g-1.min-1 and PVO2 and PVCO2 in mmHg). One interpretation of this result is that both PO2 and PCO2 are important variables in the control of blood flow in skeletal muscle the combined influence of which could account for nearly all of the hyperemia response to steady-state muscle exercise.

Relationship of pyruvate and lactate during anaerobic metabolism. V: Coronary adequacy

1961 ◽  
Vol 200 (6) ◽  
pp. 1169-1176 ◽  
Author(s):  
William E. Huckabee
Keyword(s):  
Blood Flow ◽  
Coronary Flow ◽  
Cardiac Tissue ◽  
Anaerobic Metabolism ◽  
Constant Ratio ◽  
Blood Concentrations ◽  
Arterial Blood ◽  
Anesthetized Dogs ◽  
Relationship Of ◽  
The Relationship

Veno-arterial differences of pyruvate and lactate across the myocardium in chloralose-anesthetized dogs were very variable; in any one animal they changed continually with time despite constant blood flow and arterial blood concentrations. There was a systematic tendency of v-a lactate to vary with v-a pyruvate, as expressed in the calculated "Δ excess lactate," which remained nearly constant (or, if blood flow changed, bore a constant ratio to (a-v)O2). No change in Δ excess lactate from control values occurred in nonhypoxic experiments despite marked changes in v-a differences, arterial blood composition, and coronary flow. Cardiac Δ excess lactate became positive in most animals breathing 10% O2 in N2; output of excess lactate was also observed in all those in which moderate muscular exercise was induced. This anaerobic metabolism, or change in the relationship between pyruvate and lactate exchanges, was interpreted as an indication that O2 delivery response was not adequate to meet cardiac tissue requirements during such mild stresses when judged by the standards of adequacy of the basal state.

Relation of local skin temperature and local sweating to cutaneous blood flow

1963 ◽  
Vol 18 (4) ◽  
pp. 781-785 ◽  
Author(s):  
Leo C. Senay ◽  
Leon D. Prokop ◽  
Leslie Cronau ◽  
Alrick B. Hertzman
Keyword(s):  
Blood Flow ◽  
Skin Temperature ◽  
Sweat Gland ◽  
Cutaneous Blood Flow ◽  
Local Skin ◽  
Cutaneous Vasodilatation ◽  
Local Skin Temperature ◽  
Relationship Of ◽  
The Relationship ◽  
Cutaneous Blood

The relationship of local skin temperature and the onset of sweating to the local cutaneous blood flow was studied in the forearm and calf. The purpose of the investigation was to appraise the possible relation of sweat gland activity to the cutaneous vasodilatation which has been attributed to bradykinin or to intracranial temperatures. The onset of sweating was not marked by any apparently related increases in the rate of cutaneous blood flow. On the contrary, the onset of sweating was followed often by a stabilization or even a decrease in the level of cutaneous blood flow. The relations of the latter to the local skin temperature were complex, particularly in the forearm. There appeared to be additional unidentified influences, possibly vasomotor, operating on the skin vessels during transitional phases in the relation of skin temperature to blood flow. Submitted on October 15, 1962

Effect of furosemide on pulmonary blood flow distribution in resting and exercising horses

1999 ◽  
Vol 86 (6) ◽  
pp. 2034-2043 ◽  
Author(s):  
Howard H. Erickson ◽  
Susan L. Bernard ◽  
Robb W. Glenny ◽  
M. Roger Fedde ◽  
Nayak L. Polissar ◽  
...  
Keyword(s):  
Blood Flow ◽  
Pulmonary Blood Flow ◽  
Flow Distribution ◽  
Thoroughbred Horses ◽  
Dorsal Portion ◽  
Primary Finding ◽  
Pulmonary Arterial ◽  
Relationship Of ◽  
The Relationship ◽  
Rest And Exercise

We determined the spatial distribution of pulmonary blood flow (PBF) with 15-μm fluorescent-labeled microspheres during rest and exercise in five Thoroughbred horses before and 4 h after furosemide administration (0.5 mg/kg iv). The primary finding of this study was that PBF redistribution occurred from rest to exercise, both with and without furosemide. However, there was less blood flow to the dorsal portion of the lung during exercise postfurosemide compared with prefurosemide. Furosemide did alter the resting perfusion distribution by increasing the flow to the ventral regions of the lung; however, that increase in flow was abated with exercise. Other findings included 1) unchanged gas exchange and cardiac output during rest and exercise after vs. before furosemide, 2) a decrease in pulmonary arterial pressure after furosemide, 3) an increase in the slope of the relationship of PBF vs. vertical height up the lung during exercise, both with and without furosemide, and 4) a decrease in blood flow to the dorsal region of the lung at rest after furosemide. Pulmonary perfusion variability within the lung may be a function of the anatomy of the pulmonary vessels that results in a predominantly fixed spatial pattern of flow distribution.

Application and In situ calibration of a pulsed-doppler flowmeter for blood flow measurement in crustaceans

1994 ◽  
Vol 74 (2) ◽  
pp. 455-458 ◽  
Author(s):  
C.N. Airriess ◽  
B.R. McMahon ◽  
I.J. McGaw ◽  
G.B. Bourne
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
The Body ◽  
Pulsed Doppler ◽  
Arterial Perfusion ◽  
Non Invasive ◽  
In Situ Calibration ◽  
Flow Through ◽  
Doppler Flowmeter

The pulsed-Doppler flowmeter permits continuous, non-invasive measurement of blood flow through several arteries simultaneously. Summation of volume flow rates through all arteries leaving the heart allows determination of cardiac output, stroke volume, and the percentage of cardiac output delivered to each region of the body. The use of this system for investigating changes in arterial perfusion as well as its calibration in situ are described.

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