Relationship of blood flow to pressure in the intestinal vascular bed of the dog

1962 ◽  
Vol 202 (2) ◽  
pp. 253-256 ◽  
Author(s):  
E. Clinton Texter ◽  
Steven Merrill ◽  
Melvin Schwartz ◽  
Guido Van Derstappen ◽  
Francis J. Haddy

The relationship of pressure in the superior mesenteric artery, mesenteric small artery, mesenteric small vein, and portal vein to the rate of blood flow in the superior mesenteric artery was studied in eight dogs. Total bed resistance to blood flow decreased as a function of flow over the range 20–60 ml/min but increased as a function of flow over the range 90–270 ml/min. The onset and cessation of the resistance increase were associated with pressures in the superior mesenteric artery of 64 and 205 mm Hg, respectively. These resistance changes resulted mainly from change of resistance to flow through vessels less than 0.5 mm diameter. The findings suggest that the intestinal vascular bed, like the renal vascular bed, has a local mechanism which antagonizes changes of flow rate produced by variation of arterial pressure.

1969 ◽  
Vol 47 (6) ◽  
pp. 563-569 ◽  
Author(s):  
Keith MacCannell

Ethylene and propylene glycol both decrease renal blood flow in dogs while increasing flow through the superior mesenteric artery. The decrease in renal blood flow is not a passive response to dilatation of major vascular beds since it precedes the increment in superior mesenteric arterial flow and since it can be duplicated by direct injection of glycols into the renal artery. These rheological changes in response to glycols are at least partly due to hemolysis since intravenous injection of plasma from hemolyzed blood or of crystalline hemoglobin produces the same pattern of response, which is not blocked by phenoxybenzamine. However, the production of hemoglobinemia may not be the sole explanation for the vascular responses to the glycols, since a concentration of 2 %, which does not induce detectable hemolysis, still produces the characteristic increase in superior mesenteric artery blood flow.


2021 ◽  
Author(s):  
Rinad Minvaleev ◽  
Rinat Bogdanov ◽  
David Bahner ◽  
Alexander Levitov ◽  
Andrej Kuznetsov

Abstract Objectives Medieval yoga texts claim that a special exercise of the muscles of the anterior abdominal wall, called agnisara, improves digestive function. Main objective of the study was to demonstrate change in the blood flow through superior mesenteric artery (if any) after performance of agnisara. Design and subjects: Ultrasound examination of the linear and volumetric indicators of blood flow in the superior mesenteric artery (SMA) before and after performing the agnisara yoga exercise 100 times was carried out in 12 healthy volunteers of both sexes (8 of them women). Results A significant increase in the diameter of the SMA, peak systolic and diastolic velocities, and blood flow in the superior mesenteric artery after performing the agnisara exercise 100 times was found, which contrasts with the established data on a decrease in splanchnic blood flow in humans in response to normal physical activity. Conclusion Properly performed agnisara increases blood flow to the splanchnic region, registered by the SMA, which should contribute to adequate blood supply to the gastrointestinal tract for successful performance of digestive function.


2012 ◽  
Vol 12 (3) ◽  
pp. 5-10 ◽  
Author(s):  
E Paulusova ◽  
L Stillova ◽  
K Haskova ◽  
K Matasova

Abstract Hypotrophic newborn is a newborn with birth weight below the 5th percentile weight of corresponding gestational age. Hypotrophic infants have higher morbidity and mortality in comparison with eutrophic neonates. A higher incidence of hypoglycemia, polycythemia, hyperbilirubinemia, thrombocytopenia, perinatal asphyxia and caesarean section occurs typically in hypotrophic newborns. Both, intrauterine hemodynamic dysbalance and centralization of circulation due to hypotrophy cause decreased blood flow to the splanchnic circulation after the birth. There was observed a lower increase in blood flow through the coeliac artery and superior mesenteric artery in comparison with eutrophic newborns during the first postnatal week. These facts are likely to be associated with a higher frequency of abdominal problems and necrotizing enterocolitis.


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