Scaling of osmotic regulation in mammals and birds

1983 ◽  
Vol 244 (5) ◽  
pp. R601-R606 ◽  
Author(s):  
W. A. Calder ◽  
E. J. Braun
Keyword(s):  
Water Balance ◽  
Structure And Function ◽  
Allometric Equations ◽  
Osmotic Regulation ◽  
Metabolic Rates ◽  
Renal Structure ◽  
And Function ◽  
Stressful Environments

Allometric equations provide a means of summarizing and relating the components of renal structure and function in water balance and osmotic regulation. These summary equations also serve as base lines for evaluating adaptations to stressful environments and for comparisons of kidney designs and osmotic strategies of ureotelic mammals and uricotelic birds. Many of the functions can be quantitatively related to the M3/4 scaling of metabolic rates.

Discordant effects of guanidines on renal structure and function and on regional vascular dysfunction and collagen changes in diabetic rats

Diabetes ◽  
1997 ◽  
Vol 46 (1) ◽  
pp. 94-106 ◽  
Author(s):  
J. R. Nyengaard ◽  
K. Chang ◽  
S. Berhorst ◽  
K. M. Reiser ◽  
J. R. Williamson ◽  
...  
Keyword(s):  
Vascular Dysfunction ◽  
Diabetic Rats ◽  
Structure And Function ◽  
Renal Structure ◽  
And Function

The heart as a functional unit

ESC CardioMed ◽  
2018 ◽  
pp. 76-81
Author(s):  
Philip J. Kilner ◽  
Sonya V. Babu-Narayan
Keyword(s):  
Functional Unit ◽  
Structure And Function ◽  
Morphological Features ◽  
Metabolic Rates ◽  
Evolutionary Origins ◽  
And Function

This chapter and Chapter 3.6 address the interrelatedness of heart form, structure, and function. The principle of reciprocation between the alternate contractions of atrial and ventricular cavities is outlined, and it is explained how it is enhanced with the increased output of exercise by virtue of the directions of the forces associated with changes of momentum through the looped curvatures of the heart. The human heart’s sinuous paths of flow and its fully septated, four-chamber arrangement are features shared by the hearts of other mammals and the birds, which are also warm-blooded with relatively high cardiac outputs for high metabolic rates. These morphological features are not found among the hearts of the exothermic invertebrate phyla such as worms, arthropods, or molluscs. The possible evolutionary origins and potential functional advantages of cardiac septation for mammalian life are considered. This chapter addresses the interrelatedness of macroscopic structural morphodynamics with the fluid morphodynamics of passing blood streams while Chapter 3.6 considers the smaller-scale morphodynamics of myocardium in an attempt to convey a multiscale morphodynamic interpretation of the heart form, structure, and function.

EFFECTS OF BACTERIURIA ON RENAL STRUCTURE AND FUNCTION IN THE AGING RAT

1981 ◽  
Vol 16 (5) ◽  
pp. 369
Author(s):  
M. S.F. McLachlan ◽  
L. Boylan
Keyword(s):  
Structure And Function ◽  
Renal Structure ◽  
Aging Rat ◽  
And Function

scholarly journals Radix Rehmanniae and Corni Fructus against Diabetic Nephropathy via AGE-RAGE Signaling Pathway

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Jing Chen ◽  
Yuping Chen ◽  
Anmei Shu ◽  
Jinfu Lu ◽  
Qiu Du ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Signaling Pathway ◽  
Animal Experiments ◽  
Structure And Function ◽  
Metabolic Parameters ◽  
Network Pharmacology ◽  
Active Compounds ◽  
Renal Structure ◽  
Corni Fructus ◽  
And Function

Background and Aims. Radix Rehmanniae and Corni Fructus (RC) have been widely applied to treat diabetic nephropathy (DN) for centuries. But the mechanism of how RC plays the therapeutic role against DN is unclear as yet. Methods. The information about RC was obtained from a public database. The active compounds of RC were screened by oral bioavailability (OB) and drug-likeness (DL). Gene ontology (GO) analysis was performed to realize the key targets of RC, and an active compound-potential target network was created. The therapeutic effects of RC active compounds and their key signal pathways were preliminarily probed via network pharmacology analysis and animal experiments. Results. In this study, 29 active compounds from RC and 64 key targets related to DN were collected using the network pharmacology method. The pathway enrichment analysis showed that RC regulated advanced glycosylation end product (AGE-) RAGE and IL-17 signaling pathways to treat DN. The animal experiments revealed that RC significantly improved metabolic parameters, inflammation renal structure, and function to protect the kidney against DN. Conclusions. The results revealed the relationship between multicomponents and multitargets of RC. The administratiom of RC might remit the DM-induced renal damage through the AGE-RAGE signaling pathway to improve metabolic parameters and protect renal structure and function.

scholarly journals Preservation of Renal Structure and Function at 2 Years without Calcineurin Inhibitor Use

2005 ◽  
Vol 5 (5) ◽  
pp. 1168-1168
Author(s):  
Kevin C. Abbott ◽  
Erin M. Bohen ◽  
Christina M. Yuan
Keyword(s):  
Calcineurin Inhibitor ◽  
Structure And Function ◽  
Renal Structure ◽  
And Function

Renal structure and function in insulin-dependent diabetes mellitus in man

1992 ◽  
Vol 10 (Supplement 1) ◽  
pp. S17-S20 ◽  
Author(s):  
S Michael Mauer ◽  
Pascale Lane ◽  
Dan Zhu ◽  
Paola Fioretto ◽  
Michael W. Steffes
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Dependent Diabetes Mellitus ◽  
Structure And Function ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Renal Structure ◽  
Insulin Dependent ◽  
And Function
Sign in / Sign up

Export Citation Format

Share Document