Role of intestinal calcium absorption in plasma calcium regulation of the rat

1984 ◽  
Vol 246 (5) ◽  
pp. R680-R683 ◽  
Author(s):  
F. Bronner
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Calcium Intake ◽  
Calcium Absorption ◽  
Calcium Regulation ◽  
Plasma Calcium ◽  
Intestinal Calcium Absorption ◽  
High Calcium Intake ◽  
High Calcium

Transmural calcium movement in the intestine involves both saturable and nonsaturable components, with the saturable movement subject to regulation by vitamin D and indirectly by parathyroid hormone. Under conditions of high-calcium intake, calcium absorption due to the saturable component is minimized and the numerical value of the nonsaturable component can equal that found in vitamin D-deficient or parathyroidectomized (PTX) animals on similar calcium intakes. Yet in PTX animals intestinal calcium represents a larger proportion of the calcium inflow into the central pool, and PTX animals are less able to regulate their plasma calcium than hormonally intact animals. This demonstrates that intestinal calcium input in the rat can be classified as a signal disturbing (raising) the plasma calcium.

Role of prolactin in vitamin D metabolism and calcium absorption during lactation in the rat

1982 ◽  
Vol 94 (3) ◽  
pp. 443-453 ◽  
Author(s):  
C. J. Robinson ◽  
E. Spanos ◽  
M. F. James ◽  
J. W. Pike ◽  
M. R. Haussler ◽  
...  
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Alkaline Phosphatase Activity ◽  
Plasma Levels ◽  
Calcium Absorption ◽  
High Plasma ◽  
Intestinal Calcium Absorption ◽  
Vitamin D Metabolism

Intestinal calcium absorption and plasma levels of 1,25-dihydroxycholecalciferol (1,25(OH)2D3) were measured in lactating and non-lactating rats and the effects of bromocriptine and exogenous prolactin treatment were evaluated. In lactating rats calcium absorption and plasma levels of parathyroid hormone, 1,25(OH)2D3 and alkaline phosphatase activity were significantly increased. Bromocriptine treatment significantly reduced the enhanced calcium absorption and levels of plasma 1,25(OH)2D3 and alkaline phosphatase but had no significant effect on plasma levels of parathyroid hormone. Prolactin administered with bromocriptine to lactating animals prevented all the changes observed with bromocriptine treatment alone. It was concluded that the increased plasma levels of prolactin during lactation lead to high plasma levels of 1,25(OH)2D3 which are responsible for the enhanced intestinal calcium absorption.

Vitamin D receptor genotypes and changes of bone density in physically active German women with high calcium intake

2009 ◽  
Vol 105 (02) ◽  
pp. 103-108 ◽  
Author(s):  
F. Rauch ◽  
A. Radermacher ◽  
A. Danz ◽  
U. Schiedermaier ◽  
A. Golücke ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Vitamin D Receptor ◽  
Calcium Intake ◽  
High Calcium Intake ◽  
Physically Active ◽  
High Calcium

THE ROLE OF THE THYROID IN THE INTESTINAL EFFECT OF VITAMIN D ON RACHITIC RATS

1970 ◽  
Vol 48 (4) ◽  
pp. 541-544 ◽  
Author(s):  
M. WINTER ◽  
E. MORAVA ◽  
G. SIMON
Keyword(s):  
Vitamin D ◽  
Intestinal Absorption ◽  
Calcium Absorption ◽  
Intestinal Calcium Absorption ◽  
Thyroid Glands ◽  
And Control

SUMMARY The effect of 20 i.u. vitamin D3 on the intestinal absorption of calcium was investigated in thyroidectomized and control rachitic rats. Vitamin D3 increased both duodenal and jejunal calcium absorption in the absence of the thyroid glands. These results suggest that neither thyroxine nor calcitonin are necessary for the effect of vitamin D3 on intestinal calcium absorption.

Effect of vitamin D3 (cholecalciferol) on plasma calcium and intestinal 45calcium absorption in goldfish, Carassius auratus L.

1984 ◽  
Vol 62 (1) ◽  
pp. 34-36 ◽  
Author(s):  
James C. Fenwick
Keyword(s):  
Vitamin D ◽  
Food Deprivation ◽  
Vitamin D3 ◽  
Carassius Auratus ◽  
Calcium Absorption ◽  
Plasma Calcium ◽  
Intestinal Calcium Absorption ◽  
Total Calcium ◽  
Goldfish Carassius Auratus

Goldfish that were fed as well as not fed for 2 weeks had similar plasma total calcium levels, and vitamin D3 injections during the last 6 days had no significant effect on this parameter. When fish were fed for 1 day after 13 days of food deprivation, plasma calcium increased significantly and this increase was augmented by vitamin D3 injections. This latter group also showed a chlorpromazine-sensitive increase in 45calcium absorption from perfused everted gut sacs when compared with the controls. It was concluded that vitamin D3 stimulates intestinal calcium absorption in the goldfish.

Role of vitamin D in plasma calcium regulation

1969 ◽  
Vol 216 (2) ◽  
pp. 254-262 ◽  
Author(s):  
S Hurwitz ◽  
RE Stacey ◽  
F Bronner
Keyword(s):  
Vitamin D ◽  
Calcium Regulation ◽  
Plasma Calcium

Calcium Balance in Osteoporotic Patients on Long-Term Oral Calcium Therapy with and without Sex Hormones

1982 ◽  
Vol 62 (2) ◽  
pp. 221-226 ◽  
Author(s):  
N. C. Thalassinos ◽  
D. H. Gutteridge ◽  
G. F. Joplin ◽  
T. R. Fraser
Keyword(s):  
Calcium Intake ◽  
Calcium Absorption ◽  
Concomitant Administration ◽  
Urinary Calcium ◽  
Calcium Balance ◽  
Total Calcium ◽  
High Calcium Intake ◽  
Oral Calcium ◽  
High Calcium

1. The effect of a high calcium intake (1 mmol day−1 kg−1) alone or with the concomitant administration of oestradiol and testosterone derivatives was monitored by serial calcium balances in 48 patients with osteoporosis of various types. 2. On high calcium alone there was an increase (P < 0.001) in both total calcium balance and net calcium absorption as compared with values on a simulated home intake. This effect was sustained for periods up to 10 years (mean 3.5 years) by the addition of the hormones. 3. Discontinuation of the hormones (only) produced a significant decrease in both calcium balance and nett absorption but both were still increased when compared with the initial values under simulated home calcium intake. 4. No significant change in the urinary calcium output was observed under any of the regimens.

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