Pulmonary hemodynamics and arterial oxygen saturation in pulmonary embolism

1965 ◽  
Vol 20 (2) ◽  
pp. 184-190 ◽  
Author(s):  
Paolo Caldini
Keyword(s):  
Pulmonary Embolism ◽  
Oxygen Saturation ◽  
Arterial Oxygen Saturation ◽  
Arterial Oxygen ◽  
Repeated Injection ◽  
Venous Admixture ◽  
Pulmonary Hemodynamics ◽  
Pulmonary Embolization ◽  
Mechanical Pump ◽  
The Right

Thoracotomized dogs with a reservoir and mechanical pump substitution of the right heart were subjected to pulmonary embolization by repeated injection of glass microspheres (80-120 뀅) or autologous clots (2-3 mm). Airway pressure was controlled by means of a Starling resistor connected to the expiratory line of the respirator. Following embolization with microspheres, the initial abrupt rise in pulmonary arterial pressure was followed by a more gradual increase, interpreted as due to delayed constriction of pulmonary vascular bed. Following emboli injection, systemic arterial oxygen saturation decreased to 82%, venous admixture rose to 30%. When the end-expiratory pressure was increased from 5 to 20 cm of water, the arterial oxygen saturation rose and venous admixture decreased to values not significantly different from pre-embolic levels. These findings suggest that pulmonary hypertension in pulmonary embolism is due not only to a mechanical obstruction of pulmonary vessels, but that some degree of pulmonary vasoconstriction also occurs when small-sized emboli are used. Arterial hypoxemia associated with pulmonary embolism appears to be due to perfusion of non- or poorly ventilated areas of the lung and not to significant blood flow through arteriovenous anastomoses. blood tensions; pulmonary edema; pulmonary venoarterial shunts Submitted on May 4, 1964

Detection of extrinsic bronchial compression during foreign body removal by pulse oximetry

1990 ◽  
Vol 104 (1) ◽  
pp. 50-51
Author(s):  
M. S. C. Morrissey ◽  
P. J. H. Venn ◽  
H. Y. Chan ◽  
H. Whittet
Keyword(s):  
Foreign Body ◽  
Oxygen Saturation ◽  
Pulse Oximetry ◽  
Main Bronchus ◽  
Arterial Oxygen Saturation ◽  
Arterial Oxygen ◽  
Partial Removal ◽  
Foreign Body Removal ◽  
The Right ◽  
Bronchial Compression

AbstractA case of stridor is described which was due to the presence of a foreign body in the larynx of an infant. Following partial removal, compression of the right main bronchus was detected because of continuing low arterial oxygen saturation. The use of pulse oximetry allowed this complication to be identified, and the advantages of this method of monitoring are discussed.

OXIMETER STUDIES IN NEWBORN INFANTS DURING CRYING

PEDIATRICS ◽  
1952 ◽  
Vol 9 (6) ◽  
pp. 756-763 ◽  
Author(s):  
KLARA J. PREC ◽  
DONALD E. CASSELS
Keyword(s):  
Oxygen Saturation ◽  
Arterial Oxygen Saturation ◽  
Pulmonary Ventilation ◽  
Newborn Infants ◽  
Arterial Oxygen ◽  
Direct Reading ◽  
Single Scale ◽  
The Mean ◽  
Alveolar Oxygen ◽  
The Right

The arterial oxygen saturation was determined in 135 healthy newborn infants during sleep and while crying with a direct reading single scale oximeter. In the first group, consisting of infants from one hour and 30 minutes to 3 days of age, 66% showed a decrease of oxygen saturation with crying, 27% an increase and 6.8% no change. In the second group, which includes all infants between 4 and 9 days of age, 59% showed an increase in saturation with crying, 21% a decrease and 22.4% no change. In comparison, the mean results in these two groups are in the opposite direction. These changes are statistically significant. Twenty-eight infants were studied also while breathing oxygen (73%-98.5%), and the results compared with those in room air were found to show an identical trend. It is concluded that increases in arterial oxygen saturation with crying, which occur most frequently in older infants, are probably due to an increase in alveolar oxygen tension secondary to improved pulmonary ventilation during crying. The paradoxic decrease in saturation during crying, which was found in a large percentage of infants of the younger group, is suggestive of the presence of a transitory venous-arterial shunt. This shunt could be either through atelectatic areas of the lung or through the foramen ovale, which is only functionally closed and can open whenever the pressure in the right auricle exceeds the left auricular pressure. There is some available evidence to support the latter possibility.

Efficacy and safety of balloon dilation as palliative treatment for tetralogy of Fallot

1994 ◽  
Vol 4 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Gurleen K. Sharland ◽  
Shakeel A. Qureshi ◽  
Edmund J. Ladusans ◽  
Jonathon M. Parsons ◽  
Edward J. Baker ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Tetralogy Of Fallot ◽  
Pulmonary Valve ◽  
Arterial Oxygen Saturation ◽  
Balloon Dilation ◽  
Right Ventricular Outflow Tract ◽  
Outflow Tract ◽  
Arterial Oxygen ◽  
The Mean ◽  
The Right

AbstractTwenty-six patients requiring palliation for the tetralogy of Fallot were treated by balloon dilation. The mean age at dilation was 8.5 months (range 0.5−20.6) and the mean weight 6.7 kg (range 2.6−10.7). Successful dilation was achieved in 25 patients. The mean ratio of the balloon to the diameter of the pulmonary outflow tract was 1.6 (range 1.2−2.0). The aortic oxygen saturation increased from mean±SD of 80±12.4% before to 91±4.3% after dilation (p<0.05). The pulmonary arterial oxygen saturation rose from 64±10.7% to 80±7.7% (p<0.05). Transient hypotension and arterial desaturation were noted in 19 patients during inflation of the balloon. One patient had a cardiac arrest prior to dilation and died afterwards. Seven patients had cyanotic spells related to the procedure. Attempts to cross the pulmonary valve resulted in infundibular perforation by the guide wire in one patient. Of the 24 survivors who initially had successful dilation procedures, three have needed a Blalock-Taussig shunt. Palliation without a shunt was achieved in the remaining 21 patients. In 12 patients, repeat angiography, 2.5−20 months (mean 9.1) after dilation, showed an increase in the diameter of the outflow tract from 7.1±2.1 mm before to 9.5±2.0 mm after dilation (p<0.05). Diameters of the pulmonary arteries increased from 6.3±2.2 mm on the right and 6.8±1.9 mm on the left before to 9.2±2.2 mm and 9.3±2.5 mm respectively after dilation (p<0.05 for both branches). Surgical correction has been achieved in 22 patients, 21 of these 2−22 months after balloon dilation and the other patient 20 months after construction of a shunt. At operation, the leaflets of the pulmonary valve were noted to be torn in five patients. In 12 patients, there was extensive scarring of the infundibulum. Balloon dilation of the right ventricular outflow tract achieves adequate palliation and may result in an increase in the diameter of the pulmonary valve and branches of the pulmonary trunk. It should be considered as an alternative to shunt procedures in children with tetralogy of Fallot.

scholarly journals Accuracy of two pulse-oximetry measurements for INTELLiVENT-ASV in mechanically ventilated patients: a prospective observational study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shinshu Katayama ◽  
Jun Shima ◽  
Ken Tonai ◽  
Kansuke Koyama ◽  
Shin Nunomiya
Keyword(s):  
Oxygen Saturation ◽  
Pulse Oximetry ◽  
Prospective Observational Study ◽  
Arterial Oxygen Saturation ◽  
Arterial Oxygen ◽  
Arterial Blood Gas ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Arterial Blood ◽  
Ventilated Patients

AbstractRecently, maintaining a certain oxygen saturation measured by pulse oximetry (SpO2) range in mechanically ventilated patients was recommended; attaching the INTELLiVENT-ASV to ventilators might be beneficial. We evaluated the SpO2 measurement accuracy of a Nihon Kohden and a Masimo monitor compared to actual arterial oxygen saturation (SaO2). SpO2 was simultaneously measured by a Nihon Kohden and Masimo monitor in patients consecutively admitted to a general intensive care unit and mechanically ventilated. Bland–Altman plots were used to compare measured SpO2 with actual SaO2. One hundred mechanically ventilated patients and 1497 arterial blood gas results were reviewed. Mean SaO2 values, Nihon Kohden SpO2 measurements, and Masimo SpO2 measurements were 95.7%, 96.4%, and 96.9%, respectively. The Nihon Kohden SpO2 measurements were less biased than Masimo measurements; their precision was not significantly different. Nihon Kohden and Masimo SpO2 measurements were not significantly different in the “SaO2 < 94%” group (P = 0.083). In the “94% ≤ SaO2 < 98%” and “SaO2 ≥ 98%” groups, there were significant differences between the Nihon Kohden and Masimo SpO2 measurements (P < 0.0001; P = 0.006; respectively). Therefore, when using automatically controlling oxygenation with INTELLiVENT-ASV in mechanically ventilated patients, the Nihon Kohden SpO2 sensor is preferable.Trial registration UMIN000027671. Registered 7 June 2017.

scholarly journals BIOCHEMICAL STUDIES ON SHOCK

1944 ◽  
Vol 79 (1) ◽  
pp. 9-22 ◽  
Author(s):  
Frank L. Engel ◽  
Helen C. Harrison ◽  
C. N. H. Long
Keyword(s):  
Blood Pressure ◽  
Amino Acids ◽  
Oxygen Saturation ◽  
Hepatic Artery ◽  
Arterial Oxygen Saturation ◽  
Amino Nitrogen ◽  
Arterial Oxygen ◽  
High Positive Correlation ◽  
Peripheral Tissues ◽  
Arterial Blood

1. In a series of rats subjected to hemorrhage and shock a high negative correlation was found between the portal and peripheral venous oxygen saturations and the arterial blood pressure on the one hand, and the blood amino nitrogen levels on the other, and a high positive correlation between the portal and the peripheral oxygen saturations and between each of these and the blood pressure. 2. In five cats subjected to hemorrhage and shock the rise in plasma amino nitrogen and the fall in peripheral and portal venous oxygen saturations were confirmed. Further it was shown that the hepatic vein oxygen saturation falls early in shock while the arterial oxygen saturation showed no alteration except terminally, when it may fall also. 3. Ligation of the hepatic artery in rats did not affect the liver's ability to deaminate amino acids. Hemorrhage in a series of hepatic artery ligated rats did not produce any greater rise in the blood amino nitrogen than a similar hemorrhage in normal rats. The hepatic artery probably cannot compensate to any degree for the decrease in portal blood flow in shock. 4. An operation was devised whereby the viscera and portal circulation of the rat were eliminated and the liver maintained only on its arterial circulation. The ability of such a liver to metabolize amino acids was found to be less than either the normal or the hepatic artery ligated liver and to have very little reserve. 5. On complete occlusion of the circulation to the rat liver this organ was found to resist anoxia up to 45 minutes. With further anoxia irreversible damage to this organ's ability to handle amino acids occurred. 6. It is concluded that the blood amino nitrogen rise during shock results from an increased breakdown of protein in the peripheral tissues, the products of which accumulate either because they do not circulate through the liver at a sufficiently rapid rate or because with continued anoxia intrinsic damage may occur to the hepatic parenchyma so that it cannot dispose of amino acids.

Arterial Oxygen Saturation and Posture in Acute Stroke

1993 ◽  
Vol 22 (4) ◽  
pp. 269-272 ◽  
Author(s):  
JIMMY ELIZABETH ◽  
JOSEPH SINGARAYAR ◽  
JOHN ELLUL ◽  
DAVID BARER ◽  
MICHAEL LYE
Keyword(s):  
Oxygen Saturation ◽  
Acute Stroke ◽  
Arterial Oxygen Saturation ◽  
Arterial Oxygen
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