Properties of ganglion cells with atypical receptive-field organization in retina of macaques

1978 ◽  
Vol 41 (6) ◽  
pp. 1435-1449 ◽  
Author(s):  
F. M. de Monasterio
Keyword(s):  
Electrical Stimulation ◽  
Superior Colliculus ◽  
Ganglion Cells ◽  
Receptive Fields ◽  
Optic Tract ◽  
Spatial Summation ◽  
Lateral Geniculate Body ◽  
Central Retina ◽  
Lateral Geniculate ◽  
Stimulation Of

1. About 10% of a sample of 436 cells recorded in the retina of macaques had receptive fields lacking a center-surround organization. These cells had a diffuse extrafoveal distribution, they were less frequently found in the foveal region, and their conduction latencies overlapped with those of cells (types I, III, and IV) having a center-surround organization. Three groups were distinguished. 2. Type II cells had spectrally opponent responses mediated by mechanisms having similar or identical distributions and response latency; these cells did not respond to white light. They predominated in the central retina, they usually received input from all three types of cone, they had a linear spatial summation of incomming photo-receptor signals, they lacked rod input, they had conduction latencies that were intermediate between those of the other two groups, and they could be antidromically activated by electrical stimulation of the lateral geniculate body but not of the superior colliculus. 3. Type V cells were neurons whose common characteristic was the presence of on-off responses to both small and large stimuli. One subgroup had either excitatory or inhibitory on-off responses and a silent inhibitory surround that tended to suppress cell responses and maintained activity. They were observed throughout the central retina, including the fovea; they received input from green- and red-sensitive cones, but not from blue-sensitive cones; they had a non-linear spatial summation; they had comparatively long conduction latencies; and they could be antidromically activated by electrical stimulation of either the lateral geniculate body or superior colliculus. Another subgroup lacked spontaneous activity and any type of surround. They were encountered at a retinal depth more sclerad than that of other neurons and could not be antidromically driven from the optic tract or more central structures; these cells also lacked input from blue-sensitive cones and had a nonlinear spatial summation. 4. Type VI cells were predominantly inhibited by moving stinuli in any direction of motion and failed to respond to stationary flashing stimuli; they appeared to predominate toward the perifovea and had comparatively short conduction latencies.

Superior colliculus cell responses to electrical stimulation of the retina

1977 ◽  
Vol 55 (2) ◽  
pp. 301-306 ◽  
Author(s):  
S. Molotchnikoff ◽  
P. L'archevêque
Keyword(s):  
Electrical Stimulation ◽  
Superior Colliculus ◽  
Retinal Ganglion Cells ◽  
Ganglion Cells ◽  
Optic Tract ◽  
Retinal Ganglion ◽  
Cell Responses ◽  
Prolonged Discharge ◽  
Stimulation Of

Superior colliculus cell discharges in response to electrical stimulation of the retina were investigated in rabbit. In contrast with the responses at the optic tract level both polarities evoked discharges of equal latencies suggesting a convergence of ON- and OFF-centre retinal ganglion cells upon one collicular unit. Three typical patterns of responses could be distinguished. Thus, 40% of cells reacted with a burst, 47% with a prolonged discharge, and 5% responded by a transient inhibition. The responses of the remaining cells could not be classified.

Visual cortex contribution to the organization of eye movements produced by local electrical stimulation of the cat lateral geniculate body

1987 ◽  
Vol 19 (2) ◽  
pp. 126-130
Author(s):  
V. Ya. Svetlova ◽  
N. F. Podvigin ◽  
F. N. Makarov ◽  
K. P. Fedorova ◽  
E. V. Evpyat'eva
Keyword(s):  
Electrical Stimulation ◽  
Visual Cortex ◽  
Eye Movements ◽  
Lateral Geniculate Body ◽  
Lateral Geniculate ◽  
Stimulation Of

Response properties of ganglion cells in the isolated mouse retina

1993 ◽  
Vol 10 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Charlene Stone ◽  
Lawrence H. Pinto
Keyword(s):  
Ganglion Cells ◽  
Cutoff Frequency ◽  
Receptive Fields ◽  
Spatial Summation ◽  
Mouse Retina ◽  
Sinusoidal Grating ◽  
Central Retina ◽  
X Cells ◽  
Y Cells ◽  
Receptive Field Center

AbstractWe have studied the organization of receptive fields of ganglion cells in the isolated mouse retina and have shown that the organization is similar to that of the cat. Based upon responses to circular and annular stimuli, most ganglion cells (90%; N = 83) had receptive fields with concentric center-surround organization, either ON or OFF center. The plot of response amplitude vs. stimulus area for these cells increased to a maximum (corresponding to a diameter of 10.0 ± 2.8 deg S.E.M.; N = 13) and then decreased for larger stimuli, demonstrating the presence of an antagonistic surround. The dark-adapted sensitivity (205 ± 43.8 impulses quantum−1 rod−1; mean ± S.E.M.) did not differ from that measured for the intact preparation. We found a subset of OFF-center cells for which the dark discharge was very regular (mean coefficient of variation = 0.30). Using sinusoidal grating stimuli, we classified ganglion cells as X-like (87%) and Y-like (13%) based on spatial summation properties and the presence of subunit activity in the receptive-field center. We found no difference in the spatial-frequency preference between X-like and Y-like cells in the central retina (high cutoff frequency, 0.20 ± 0.014 cycle/deg, mean ± S.E.M.), in contrast to the marked difference between X cells and Y cells in the cat. Thus, ganglion cell receptive fields in the mouse retina resemble those of the cat, although the spatial characteristics of the receptive fields in the central retina are more homogeneous. This homogeneity would simplify the comparison of retinas from normal and mutant strains of the mouse.

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