scholarly journals cAMP and Mitochondria

Physiology ◽  
2013 ◽  
Vol 28 (3) ◽  
pp. 199-209 ◽  
Author(s):  
Federica Valsecchi ◽  
Lavoisier S. Ramos-Espiritu ◽  
Jochen Buck ◽  
Lonny R. Levin ◽  
Giovanni Manfredi
Keyword(s):  
Protein Phosphorylation ◽  
Adenylyl Cyclase ◽  
Regulatory Mechanism ◽  
Mitochondrial Proteins ◽  
Camp Signaling ◽  
Metabolic Adaptation ◽  
Mitochondrial Bioenergetics ◽  
Soluble Adenylyl Cyclase

Phosphorylation of mitochondrial proteins has emerged as a major regulatory mechanism for metabolic adaptation. cAMP signaling and PKA phosphorylation of mitochondrial proteins have just started to be investigated, and the presence of cAMP-generating enzymes and PKA inside mitochondria is still controversial. Here, we discuss the role of cAMP in regulating mitochondrial bioenergetics through protein phosphorylation and the evidence for soluble adenylyl cyclase as the source of cAMP inside mitochondria.

Increased levels of calcium-sensitive adenylyl cyclase subtypes in the limbic system of alcoholics: evidence for a specific role of cAMP signaling in the human addictive brain

2001 ◽  
Vol 895 (1-2) ◽  
pp. 233-237 ◽  
Author(s):  
Megumi Yamamoto ◽  
Sabine Pohli ◽  
Nuria Durany ◽  
Hiroki Ozawa ◽  
Toshikazu Saito ◽  
...  
Keyword(s):  
Adenylyl Cyclase ◽  
Limbic System ◽  
Specific Role ◽  
Camp Signaling

scholarly journals Intracellular cAMP signaling by soluble adenylyl cyclase

2011 ◽  
Vol 79 (12) ◽  
pp. 1277-1288 ◽  
Author(s):  
Martin Tresguerres ◽  
Lonny R. Levin ◽  
Jochen Buck
Keyword(s):  
Adenylyl Cyclase ◽  
Camp Signaling ◽  
Intracellular Camp ◽  
Soluble Adenylyl Cyclase

scholarly journals Spatial resolution of cAMP signaling by soluble adenylyl cyclase

2016 ◽  
Vol 214 (2) ◽  
pp. 125-127 ◽  
Author(s):  
Giusi Caldieri ◽  
Sara Sigismund
Keyword(s):  
Plasma Membrane ◽  
Adenylyl Cyclase ◽  
G Protein ◽  
Spatial Resolution ◽  
Camp Signaling ◽  
Receptor Signaling ◽  
Soluble Adenylyl Cyclase ◽  
Spatial Encoding ◽  
Cell Biol ◽  
G Protein Coupled

G protein–coupled receptor signaling starts at the plasma membrane and continues at endosomal stations. In this issue, Inda et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512075) show that different forms of adenylyl cyclase are activated at the plasma membrane versus endosomes, providing a rationale for the spatial encoding of cAMP signaling.

scholarly journals Protective role of soluble adenylyl cyclase against reperfusion-induced injury of cardiac cells

2019 ◽  
Vol 1865 (1) ◽  
pp. 252-260 ◽  
Author(s):  
Laura Rinaldi ◽  
Sofya Pozdniakova ◽  
Vignesh Jayarajan ◽  
Christian Troidl ◽  
Yaser Abdallah ◽  
...  
Keyword(s):  
Adenylyl Cyclase ◽  
Protective Role ◽  
Cardiac Cells ◽  
Soluble Adenylyl Cyclase

scholarly journals The role of soluble adenylyl cyclase in neurite outgrowth

2014 ◽  
Vol 1842 (12) ◽  
pp. 2561-2568 ◽  
Author(s):  
Travis L. Stiles ◽  
Michael S. Kapiloff ◽  
Jeffrey L. Goldberg
Keyword(s):  
Adenylyl Cyclase ◽  
Neurite Outgrowth ◽  
Soluble Adenylyl Cyclase
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