scholarly journals Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach

2009 ◽  
Vol 2009 ◽  
pp. 1-7 ◽  
Author(s):  
Ulrich Ronellenfitsch ◽  
Wilko Staiger ◽  
Georg Kähler ◽  
Philipp Ströbel ◽  
Matthias Schwarzbach ◽  
...  
Keyword(s):  
Laparoscopic Resection ◽  
Gastrointestinal Stromal Tumour ◽  
Operation Time ◽  
Oncologic Outcome ◽  
Oncological Outcome ◽  
Stromal Tumour ◽  
Perioperative Outcomes ◽  
Gastric Gist ◽  
Gastric Gists

Background. Surgery remains the only curative treatment for gastrointestinal stromal tumour (GIST). Resection needs to ensure tumour-free margins while lymphadenectomy is not required. Thus, partial gastric resection is the treatment of choice for small gastric GISTs. Evidence on whether performing resection laparoscopically compromises outcome is limited. Methods. We compiled patients undergoing laparoscopic resection of suspected gastric GIST between 2003 and 2007. Follow-up was performed to obtain information on tumour recurrence. Results. Laparoscopic resection with free margins was performed in 21/22 patients. Histology confirmed GIST in 17 cases, 4 tumours were benign neoplasms. Median operation time and postoperative stay for GIST patients were 130 (range 80–201) mins and 7 (range 5–95) days. Two patients experienced stapler line leakage necessitating surgical revision. After median follow-up of 18 (range 1–53) months, no recurrence occurred. Conclusions. Laparoscopic resection of gastric GISTs yields good perioperative outcomes. Oncologic outcome needs to be assessed with longer follow-up. For posterior lesions, special precaution is needed. Laparoscopic resection could become standard for circumscribed gastric GISTs if necessary precautions for oncological procedures are observed.

Post-chemotherapy modified template retroperitoneal lymph node dissection in patients with nonseminomatous germ cell tumours

2021 ◽  
Author(s):  
Murat Zor ◽  
Sercan Yilmaz ◽  
Bahadir Topuz ◽  
Engin Kaya ◽  
Serdar Yalcin ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Germ Cell ◽  
Residual Disease ◽  
Germ Cell Tumors ◽  
Operation Time ◽  
Long Term Results ◽  
Perioperative Outcomes ◽  
Retroperitoneal Lymph Node Dissection

Abstract Introduction/background: Although a full bilateral template RPLND is thought to be the standard of care for the management of postchemotherapy retroperitoneal residual masses for nonseminomatous germ cell tumors (NSGCT), in the past decade modified templates have become increasingly popular. In this study, we aimed to present our oncological and perioperative outcomes of consecutive seventeen NSGCT patients who underwent a modified template unilateral PC-RPLND for retroperitoneal residual disease. Materials and Methods: We retrospectively evaluated the medical records of 17 consecutive NSGCT patients who underwent modified template unilateral PC-RPLND in our university hospital between 2017 and 2020. All patients had normal serum tumour markers with residual disease in the retroperitoneum. Surgical characteristics including the size of the retroperitoneal residual mass, residual tumor pathology, removed lymph nodes, positive percentage of removed lymph nodes, accompanying operations, complications, mean operation time and hospital stay, and long-term results including survival and antegrade ejaculation were evaluated. Results: Eleven patients underwent left and six right-sided surgery. Median residual lymph node diameter was 41mm. Median hospitalisation time was 3.5 days. Median follow-up time was 10.5 months. Necrosis/fibrosis was seen in 6 patients, and teratoma in 11 patients. No viable tumour was seen. No patients died in the follow-up period. None of the patients relapsed during follow-up. Ten/seventeen patients had antegrade ejaculation. Conclusions: Modified template unilateral PC-RPLND leads to very good oncological outcomes with decreased perioperative morbidity as well as better antegrade ejaculation rates. Low volume retroperitoneal disease seems to fit this procedure best.

scholarly journals Gastric IgG4-Related Autoimmune Fibrosclerosing Pseudotumour: A Novel Location

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Katie E. Rollins ◽  
Samir P. Mehta ◽  
Maria O'Donovan ◽  
Peter M. Safranek
Keyword(s):  
Weight Loss ◽  
Histological Examination ◽  
Laparoscopic Resection ◽  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour ◽  
Gastric Body ◽  
Resected Specimen

We describe the first reported case of an IgG4-related autoimmune fibrosclerosing pseudotumour located in the stomach of a 75-year old woman presenting with weight loss and vomiting. A lesion was detected in the gastric body at endoscopy. Subsequent characterisation by CT was suggestive of a gastrointestinal stromal tumour. Following laparoscopic resection, the patient recovered uneventfully. Histological examination of the resected specimen revealed an IgG4-related fibrosclerosing pseudotumour, a novel location for this histopathological entity.

scholarly journals Follow-up strategies for patients with gastrointestinal stromal tumour treated with or without adjuvant imatinib after surgery

2015 ◽  
Vol 51 (12) ◽  
pp. 1611-1617 ◽  
Author(s):  
H. Joensuu ◽  
J. Martin-Broto ◽  
T. Nishida ◽  
P. Reichardt ◽  
P. Schöffski ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour ◽  
Adjuvant Imatinib

scholarly journals Safety and application of laparoscopic gastrectomy for benign gastric disease and gastric cancer

2011 ◽  
Vol 93 (1) ◽  
pp. 17-21 ◽  
Author(s):  
MK Zia ◽  
G Morris-Stiff ◽  
A Luhmann ◽  
R Jeffries ◽  
O Ehsan ◽  
...  
Keyword(s):  
Laparoscopic Gastrectomy ◽  
Malignant Disease ◽  
Laparoscopic Resection ◽  
Outlet Obstruction ◽  
Gastrointestinal Stromal Tumour ◽  
Gastric Disease ◽  
D2 Lymphadenectomy ◽  
Major Morbidity ◽  
Tumour Characteristics

INTRODUCTION Laparoscopic gastrectomy is rapidly expanding despite reservations by some surgeons regarding its safety and radicality. The aim of this study was to evaluate patients undergoing laparoscopic gastrectomy for both benign and malignant disease with particular emphasis on technical feasibility, safety, effectiveness and complications. PATIENTS AND METHODS Review of prospectively collected data of patients who underwent laparoscopic gastrectomy from May 2005 to September 2009 under the care of one consultant surgeon. RESULTS A total of 61 laparoscopic gastrectomies were performed (35 men and 26 women) with a median age of 68 years (range, 41–90 years). There were 39 distal gastrectomies (19 adenocarcinoma, 6 gastrointestinal stromal tumour [GIST], 4 benign gastric outlet obstruction, 4 high-grade dysplasia in gastric adenomas, 4 non-healing ulcers, 2 gastric antral vascular ectasia [GAVE]); 15 sub-total gastrectomies (13 adenocarcinomas, 2 GIST); and 7 total gastrectomies (5 adenocarcinomas, 1 GIST, 1 carcinoid). Median follow-up was for 48 months (range, 1–72 months). There was one death, two major and six minor complications. All patients with complications made a satisfactory recovery. CONCLUSIONS Laparoscopic gastrectomy is associated with a low mortality (1.75%) and major morbidity (3.50%). Although technically demanding, especially when a D2 lymphadenectomy is performed, our results have shown that tailored laparoscopic resection based on tumour characteristics with either D1 or D2 lymphadenectomy results in good surgical and oncological outcomes.

scholarly journals PRIMARY GASTROINTESTINAL STROMAL TUMOUR OF THE PROSTATE: A CASE REPORT OF A RARE TUMOUR

2018 ◽  
Vol 4 (2) ◽  
Author(s):  
Muhammad Arshad Irshad Khalil ◽  
Nouman Khan ◽  
Azfar Ali ◽  
Khurram Mir
Keyword(s):  
Case Report ◽  
Prostate Specific Antigen ◽  
Bladder Outlet Obstruction ◽  
Specific Antigen ◽  
Outlet Obstruction ◽  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour ◽  
Rare Tumour ◽  
Normal Prostate

A 70-year-old gentleman underwent prostatectomy for bladder outlet obstruction due to enlarged prostate and was found to have primary extragastrointestinal stromal tumour (EGIST). He has been started on imatinib therapy and is presently on follow-up. Prostatic EGIST should be one of the differential diagnoses in patients with enlarged prostate with normal prostate-specific antigen levels.Key words: Prostate, gastrointestinal stromal tumour, PSA  

Recurrent paediatric gastrointestinal stromal tumour of the stomach after 11-years follow-up period – Case report and review of the literature

2021 ◽  
Vol 11 (4) ◽  
pp. 184
Author(s):  
MieAli Mohamed ◽  
KhadigaM Ali ◽  
IkbalA Elkholy ◽  
AhmedY Altonbary ◽  
Ahmed Abdallah ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour ◽  
Review Of The Literature

Multiple Cutaneous and Uterine Leiomyomas Associated with Gastric Gist

2005 ◽  
Vol 9 (6) ◽  
pp. 332-335
Author(s):  
Manisha Lamba ◽  
Shailendra Verma ◽  
Robert Prokopetz ◽  
Tadeusz A. Pierscianowski ◽  
Maha Jabi ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumour ◽  
Partial Gastrectomy ◽  
Interesting Case ◽  
Uterine Leiomyomas ◽  
Stromal Tumour ◽  
Gastric Gist ◽  
Uterine Leiomyomata ◽  
Familial Cases ◽  
Clinical Observations ◽  
Therapeutic Measures

Background: There are a number of reports documenting familial cases of leiomyomatosis cutis associated with uterine leiomyomata. However, to our knowledge, the association of gastrointestinal stromal tumour (GIST) with this entity has not as yet been reported. We report an interesting case of cutaneous leiomyomatosis, metachronous uterine leiomyomata, and a gastric GIST in a 43-year-old woman. Observation: The patient had previously undergone two separate uterine myomectomies at ages 25 and 26 years, respectively, followed by a hysterectomy at 27 years. At 36 years she underwent partial gastrectomy for excision of GIST and this was followed by the development of extensive, symptomatic cutaneous leiomyomata at 43 years. In the report, we have documented histological, immunohistochemical and clinical observations and furthermore report on the therapeutic measures undertaken. Conclusion: We report an interesting association of cutaneous leiomyomatosis, uterine leiomyomas and GIST.

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