scholarly journals Inflammatory Myofibroblastic Bladder Tumor in a Patient with Von Recklinghausen's Syndrome

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Eleftherios Chatzidarellis ◽  
Evangelos Mazaris ◽  
Andreas Skolarikos ◽  
Demonakou Maria ◽  
Iraklis Mitsogiannis ◽  
...  

Myofibroblastic tumor, also known as inflammatory pseudotumor or pseudosarcoma, is a benign tumor with mesenchymal origin. Bladder location is very uncommon. We report the case of a 58-year-old man with a history of von Recklinghausen's disease who complained for painless macroscopic hematuria 5 months after suprapubic prostatectomy. The radiograph evaluation revealed a bladder tumor, and the pathologic examination following a transurethral resection showed inflammatory myofibroblastic tumor of the bladder. The patient finally underwent a radical cystectomy due to the uncertain pathogenesis of inflammatory myofibroblastic tumor as well as the rarity of cases published on bladder tumors in Von Recklinghausen's patients.

2021 ◽  
Vol 74 (1-2) ◽  
pp. 41-44
Author(s):  
Stevan Stojanovic ◽  
Zarko Dimitric ◽  
Ivan Levakov ◽  
Mladen Popov ◽  
Sandra Trivunic-Dajko ◽  
...  

Introduction. Inflammatory myofibroblastic tumor of the bladder or inflammatory pseudotumor is benign in nature. It is also known as a pseudotumor, because it macroscopically mimics infiltrative tumors of the bladder. The first inflammatory pseudotumor ever described was found in the lungs. In the 80s of the last century, it was first described in the urinary bladder. Its etiology is unknown and the incidence is extremely rare. Case Report. We present a case of a 46-year-old man who came to the Emergency Center for the first time due to an unpleasant feeling when urinating, painless hematuria and appearance of blood clots during urination. An urgent diagnosis revealed a tumor mass in the bladder. Additional diagnostics and surgical treatment was performed by transurethral electroresection of the urinary bladder. After the histopathological examination, an inflammatory myofibroblastic tumor of the bladder was diagnosed. The patient was discharged on the third day of admission. On control examinations, the patient underwent only cystoscopy and ultrasonography. No recurrences were observed. Conclusion. A review of the available literature showed that in such cases, after transurethral resection of bladder tumor, most urologists opted for more radical surgical procedures. After a two-year follow-up, we proved that a tumor of the bladder can be kept under control after transurethral resection of bladder tumor, without recurrence, by regular monitoring using ultrasonography and cystoscopy.


2020 ◽  
Vol 21 (2) ◽  
pp. 120-126
Author(s):  
Alamgir Md ◽  
Karim Km Monwarul ◽  
Nandy SP ◽  
Md Monwar Ul Haque ◽  
Sakhawat Mahmud Khan

Objective: The aim of the study was to compare the endoscopic versus percutaneous approach (blind) to control the obturator jerk in patients undergoing transurethral resection of bladder tumors under spinal anesthesia. Materials and methods: A prospective observational study was performed in Department of Urology, Chittagong Medical College, Chittagong and some Private Hospitals (Ltd.) in Chittagong city during the period from January 2016 to June 2016. Total 100 patients were grouped into two, on alternate basis. Fifty(50) patients in group- A conducted with endoscopic infiltration with 20ml of injection 2% lignocaine at the bladder tumor base and another 50 patients in group-B, conducted with blind percutaneous technique with same drug and volume ( 20ml inj.2% lignocaine) to control obturator jerk. Severity of obturator jerk in both procedure, percentage of complete resection, ONB procedure related time, ONB procedure related complications and surgeon’s satisfaction level were recorded and compared between two approaches. Chi-square analysis was performed to compare the ease of approach and outcome of the two techniques. A value of P<0.05 was considered statistically significant. Results: The mean age of the patients were 59.44+7.681. In group-A, 50 patients were given inj. 2% lignocaine endoscopically at the bladder tumor base to control obturator jerk. Twenty five patients (50%) had no jerk, 20 patients(40%) developed mild jerk and 5 patients (10%) developed moderate jerk and no patients developed severe jerk. Second attempt was taken in moderate jerk patients (5 patients) and succeeded in 3(6%) patients. So, in this group, complete resection of bladder tumor was possible in 96%. In group B, complete resection of bladder tumor was possible in 84%. Statistical analysis was done and result is significant in case of endoscopic procedure to control obturator jerk(p<0.05). ONB Procedure related time was <20 mins. in 32(64%) patients in group-A and 45 (90%) patients in group- B. 20 mins. or more time was required for 18 (36%) patients in group-A and 5 (10%) patients in group-B. Statistical analysis was done and result is significant in percutaneous (blind) technique (p<0.05). ONB procedure related complications in group-A and Group –B were noted. Statistical analysis was done and result is insignificant (p>0.05). Surgeons satisfaction level were recorded on the basis of obturator jerk block and complete resection and which was statistically significant in favour of endoscopy group (p<0.05). Conclusion: It is concluded that endoscopic injection of 2% lignocaine into the bladder tumor base is better in case of jerk elimination and complete resection than blind percutaneous approach. Though, ONB procedure related time was significantly less in percutaneous group. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.120-126


2017 ◽  
Vol 4 (4) ◽  
pp. 1469
Author(s):  
Sreejayan M. P. ◽  
Arun S.

Inflammatory pseudo tumor (IPT) also known as inflammatory myofibroblastic tumor (IMT) is a tumor like mass of inflammatory origin. It is a pseudo sarcomatous lesion that has been reported most commonly in liver, followed by lung, mesentery and omentum but very rarely seen in esophagus. Proliferation of myofibroblastic cells is more in IMT. In IPT it is more of an inflammatory reactive or regenerative entity and has an overlapping with immunoglobulin G4-related disease. Lesion often mimics malignancy. A 20 year old male patient with history of dysphagia, more for liquids, underwent CT thorax, showing dilated oesophagus, with a moderately contrast enhancing eccentric soft tissue density lesion involving mid and lower esophagus extending for a length of 6cm. Patient underwent right thoracotomy, and a 5x3x3cm hard lesion involving lower esophagus was excised. Histopathology pointed towards inflammatory myofibroblastic tumor or inflammatory pseudotumor. Proliferation of myofibroblastic cells is more in IMT. In IPT it is more of an inflammatory reactive or regenerative entity and has an overlapping with immunoglobulin G4-related disease. Lesion often mimics malignancy.


2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Jalal Eddine El Ammari ◽  
Youness Ahallal ◽  
Mohammed Jamal El Fassi ◽  
Moulay Hassan Farih

Introduction. Primary melanoma of the urinary bladder is very rare. As far as we know, 19 cases have been reported worldwide, usually as case reports.Case Presentation. We present a 71-year-old male patient presented with a 2-month history of hematuria. Ultrasonography revealed a 5-cm-size mass located in the bladder trigone. A transurethral resection of the bladder tumor (TURBT) revealed a malignant melanoma. Evaluation for metastatic disease was negative. The patient deceased five months later before radical treatment could be performed.Conclusion. This is one more reported case of primary melanoma of the urinary bladder. The previously reported cases of bladder melanoma are reviewed. Therapy and prognosis are discussed.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Natsuko Nakazaki ◽  
Masayoshi Zaitsu ◽  
Koji Mikami ◽  
Shunsuke Yui ◽  
Ayumi Kanatani ◽  
...  

Human papillomaviruses (HPVs) are associated with proliferative lesions in a variety of human epithelial types. A 38-year-old female presented with a diagnosis of urethral condyloma acuminatum. She underwent transurethral resection of the urethral condyloma. At that time, multiple (five) bladder tumors were simultaneously found and also removed by transurethral resection. Four of the bladder tumors were diagnosed as squamous papilloma, and the other was urothelial inverted papilloma. Postoperative course was uneventful. Genomic DNA was extracted from 10 μm thick sections of each bladder tumor as well as urethral condyloma. Then, 16 types of HPV DNA sequences were assessed with the PapiPlex method using genomic DNA samples extracted from each bladder tumor as well as urethral condyloma. HPV-11 was detected in DNA extracted from the urethral condyloma, while no HPV DNA sequences were positive in any of the genomic DNA samples extracted from the bladder tumors.


2021 ◽  
Vol 8 ◽  
Author(s):  
Christian Daniel Fankhauser ◽  
Marian Severin Wettstein ◽  
Luca Afferi ◽  
Nico Christian Grossmann ◽  
Hugh Mostafid

Transurethral resection of bladder tumors (TURBT) represents the cornerstone in diagnosis and treatment of bladder cancer but recurrence is observed in up to 80% and over- or understaging with TURBT is common. A more recent development to overcome these limitations represents en-bloc resection of bladder tumors (ERBT) which offers several advantages over TURBT. In this report, we briefly review studies assessing outcomes of bladder cancer patients undergoing ERBT. Most randomized and non-randomized trial demonstrate improvement in clinical outcomes for ERBT over TURBT, however more pathological and translational studies are warranted.


1992 ◽  
Vol 59 (1_suppl) ◽  
pp. 176-178
Author(s):  
G. Lissoni ◽  
G. Galbiati ◽  
R. Borin ◽  
M. Ferruti ◽  
C. Milani

The authors report their results in adjuvant immunotherapy with B.C.G. after TUR for superficial and multicentric bladder tumors (Ta-T1). After TURB a cycle of intravesical immunotheraphy with 150 mg of BCG (Bacillus Calmette-Guerin) is performed once a week for 6 weeks, ther every 2 weeks for 6 times and finally once a month for 1 year. (16.5 months of treatment). Controls with CTM and cystoscopy are performed periodically. 63 patients have been treated: 20 (60.6%) are free from disease with follow-up of 18–36 months; 87.5% of patients who had BCG as immunotherapy after first TUR for bladder tumor, are free from disease. Comparing their results with experiences reported in literature with Mytomicin and Doxorubicin, the authors think that adjuvant immunotherapy with BCG is actually the best local treatment for these tumors. Some patients (25%) had slight troubles because of therapy but only in 3 cases (9.09%) treatment was stopped. In conclusion intravesical therapy with BCG significantly changes natural history of superficial bladder tumor, increasing the time free from disease (in our experience: 27 months).


Sign in / Sign up

Export Citation Format

Share Document