scholarly journals Cryopreservation of Parathyroid Glands

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Marlon A. Guerrero
Keyword(s):  
Quality Of Life ◽  
Primary Hyperparathyroidism ◽  
Parathyroid Tissue ◽  
Parathyroid Glands ◽  
Permanent Hypoparathyroidism ◽  
Parathyroid Surgery ◽  
Postoperative Surveillance ◽  
Current Role

The risk of permanent hypoparathyroidism following thyroid and parathyroid surgery is around 1% in the hands of experienced endocrine surgeons. Although this complication is rare, rendering a patient permanently aparathyroid has significant consequences on the health and quality of life of the patient. Immediate autotransplantation of parathyroid glands that are injured or unintentionally removed offers the best possibility of graft viability and functionality. However, since the majority of cases of hypoparathyroidism are transient, immediate autotransplantation can complicate postoperative surveillance in certain patients, especially those with primary hyperparathyroidism. Cryopreservation of parathyroid tissue is an alternate technique that was developed to treat patients with permanent hypoparathyroidism. This method allows for parathyroid tissue to be stored and then autotransplanted in a delayed fashion once permanent hypoparathyroidism is confirmed. This article provides a contemporary review on cryopreservation of parathyroid tissue and its current role in thyroid and parathyroid surgery.

scholarly journals Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Fernando Mendoza-Moreno ◽  
Ángel Rodriguez-Pascual ◽  
María Rocío Díez-Gago ◽  
Marina Pérez-González ◽  
Laura Jiménez‐Alvárez ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Parathyroid Gland ◽  
Imaging Techniques ◽  
High Sensitivity ◽  
Parathyroid Glands ◽  
Parathyroid Surgery ◽  
Thyroid Lobe ◽  
The Impact ◽  
Supernumerary Gland

Introduction. The variability of the location of the parathyroid glands is directly related to the events that occur during embryonic development. The impact that an individual submits more than four parathyroid glands is close to 13%. However the presentation of a parathyroid adenoma in a supernumerary gland is an uncommon event. Case report. A 30-year-old man diagnosed with primary hyperparathyroidism with matching findings on ultrasonography and scintigraphy for parathyroid adenoma localization lower left regarding the thyroid gland. A cervicotomy explorer showed four orthotopic parathyroid glands. The biopsy of the inferior left gland was normal. No signs of adenoma were seen in the biopsy. Following mobilization of the ipsilateral thyroid lobe, fifth parathyroid gland was found increased significantly in size than proceeded to remove, confirming the diagnosis of adenoma. After the excision, the levels of serum calcium and parathyroid hormone were normalized. Conclusions. The presentation of a parathyroid adenoma in a supernumerary gland is a challenge for the surgeon. The high sensitivity having different imaging techniques has been a key to locate preoperatively the pathological parathyroid gland. Analytical or clinical persistence of primary hyperparathyroidism after parathyroid surgery can occur if the location of the adenoma is a supernumerary or ectopic gland location.

scholarly journals Lower quality of life in longstanding mild primary hyperparathyroidism

2013 ◽  
Vol 57 (2) ◽  
pp. 139-143 ◽  
Author(s):  
Andreia Veras ◽  
Juliana Maia ◽  
Patricia Mesquita ◽  
Catia Eufrazino ◽  
Francisco Bandeira
Keyword(s):  
Quality Of Life ◽  
Primary Hyperparathyroidism ◽  
Functional Capacity ◽  
General Health ◽  
Sf 36 ◽  
Significant Difference ◽  
Mild Primary Hyperparathyroidism ◽  
Recent Diagnosis ◽  
Time Since Diagnosis

OBJECTIVE: To describe the non-classical manifestations and quality of life in patients with primary hyperparathyroidism (PHPT). SUBJECTS AND METHODS: We evaluated non-classical manifestations and quality of life of 22 patients with PHPT using the SF-36 questionnaire according to the time since diagnosis. RESULTS: In the scores of quality of life, a significant difference was found comparing the groups with previous and recent diagnosis of PHPT in terms of functional capacity (39 + 22.83 vs. 76.25 + 22.37; p = 0.001), limitation of physical aspects (30 + 38.73 vs. 75 + 21.32; p = 0.006), general health (57.20 + 19.16 vs. 77.75 + 15.70; p = 0.012), and vitality (49.00 + 21.19 vs. 70.00 + 24.12; p = 0.044). CONCLUSION: We found a significant difference in quality of life in relation to the time of the diagnosis of PHPT.

Impaired physical function and evaluation of quality of life in normocalcemic and hypercalcemic primary hyperparathyroidism

Bone ◽  
2020 ◽  
Vol 141 ◽  
pp. 115583
Author(s):  
Lara Voss ◽  
Maira Nóbrega ◽  
Leonardo Bandeira ◽  
Luiz Griz ◽  
Pedro Augusto Sampaio Rocha-Filho ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Primary Hyperparathyroidism ◽  
Physical Function

The Influence of Surgical Approach on Quality of Life After Parathyroid Surgery

2008 ◽  
Vol 15 (6) ◽  
pp. 1559-1565 ◽  
Author(s):  
Joel T. Adler ◽  
Rebecca S. Sippel ◽  
Herbert Chen
Keyword(s):  
Quality Of Life ◽  
Surgical Approach ◽  
Parathyroid Surgery

scholarly journals Quality of Life After Surgery or Surveillance for Asymptomatic Primary Hyperparathyroidism

Medicine ◽  
2015 ◽  
Vol 94 (23) ◽  
pp. e931 ◽  
Author(s):  
Shih-Ping Cheng ◽  
Jie-Jen Lee ◽  
Tsang-Pai Liu ◽  
Po-Sheng Yang ◽  
Sung-Chen Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Primary Hyperparathyroidism ◽  
Asymptomatic Primary Hyperparathyroidism

scholarly journals Re-explorative Parathyroid Surgery for Persistent and Recurrent Primary Hyperparathyroidism

2011 ◽  
Vol 3 (3) ◽  
pp. 107-111 ◽  
Author(s):  
Karolina Afors ◽  
Rachel L O'Connell ◽  
Martin H Thomas
Keyword(s):  
Primary Hyperparathyroidism ◽  
Imaging Techniques ◽  
Parathyroid Tissue ◽  
Parathyroid Surgery ◽  
Redo Surgery ◽  
Normal Gland ◽  
Primary Surgery ◽  
High Calcium ◽  
Targeted Approach

ABSTRACT Primary hyperparathyroidism (HPT) is treated by parathyroidectomy. Excision of abnormal parathyroid tissue is curative in the majority of cases. Postoperative persistent or recurrent HPT has been reported up to 30%. The purpose of this study was to evaluate the role of imaging techniques and determine the efficacy of reexplorative surgery. A total of 306 patients underwent parathyroidectomy between 2000 and 2009. Twelve patients (3.9%) were not cured. Two patients declined further treatment, the other 10 patients underwent further investigation and surgery. Imaging and results of redo surgery together with associated complications were evaluated. All 10 patients were investigated with sestamibi, which accurately localized aberrant parathyroid tissue in three cases and ultrasound scans which also localized three cases. CT was useful in one of the three cases for which it was used. PET and MRI were not helpful. Twelve glands were resected, six adenomas, five hyperplastic and one normal gland. Nine of the 10 reoperated patients became normocalcemic. Complications included a bilateral recurrent laryngeal paresis. In total, 317 operations were performed and 303 of 306 (99%) patients were cured. Redo surgery for HPT is challenging and carries higher risks than primary surgery. Sestamibi and ultrasound scans are the most helpful imaging modalities. When there is concordance a targeted approach may be considered, otherwise a more extensive dissection is required. Redo parathyroid surgery should be considered, even if scans are unhelpful, for patients who are symptomatic or young or have a persistently high calcium level.

Sign in / Sign up

Export Citation Format

Share Document