scholarly journals The Role of Lymph Node Fine-Needle Aspiration in Penile Cancer in the Sentinel Node Era

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Maria Carmen Mir ◽  
Olivia Herdiman ◽  
Damien M. Bolton ◽  
Nathan Lawrentschuk
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Sentinel Node ◽  
Fine Needle Aspiration ◽  
Penile Cancer ◽  
Needle Aspiration ◽  
Complication Rates ◽  
Fine Needle ◽  
Inguinal Lymph Nodes ◽  
Lymph Nodes Metastasis

Penile squamous cell carcinoma (SCC) is an uncommon condition in Western countries. Inguinal lymph nodes dissection can be curative in 20%–60% of node positive patients. However, there is a high complication rates from the dissection, thus accurate diagnosis of inguinal lymph nodes metastasis is required. Current non invasive methods to detect lymph nodes metastasis are unreliable. Dynamic Sentinel Node Biopsy (DNSB), ultrasonography (US), and fine needle aspiration (FNA) cytology were proposed to in an attempt to detect sentinel lymph node (SLN). Despite the initial high rate of false negative results, recent DSNB showed improved survival compared to wait and see policy as well as reduced mortality compared to prophylactic inguinal lymphadenectomy. In addition, the US guided FNA shown 100% of specificity in detecting clinically occult lymph nodes metastasis. We proposed an algorithm for management of lymph nodes in penile cancer and suggest that FNA with US guidance should be performed in all high risk patients and that therapeutic dissection should be performed if findings are positive.

scholarly journals Distribution of Various Malignant Lesions in Lymph Node Cytology – A 1 Year Population Based Study from a Tertiary Care Centre in North-East India

2021 ◽  
Vol 8 (17) ◽  
pp. 1090-1094
Author(s):  
Badrinath Venkatesh ◽  
Khagokpam Ambala Devi ◽  
Soram Gayatri Gatphoh
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Undifferentiated Carcinoma ◽  
Metastatic Tumour ◽  
Fine Needle ◽  
North East ◽  
Malignant Lesions

BACKGROUND Lymph nodes (LN) are an integral component of the immune system. Enlarged lymph nodes are a prime target for fine needle aspiration (FNA). Lymph nodes greater than 1 to 2 cm are an immediate source of concern. Lymphadenopathy is a common presenting symptom in various diseases. Fine needle aspiration cytology (FNAC) confirms the presence of metastatic disease and gives a clue regarding its nature and origin of primary malignancy. In many metastatic malignancies, FNAC may be the only tool for diagnosis and further management of the patients. We intend to assess the cytomorphological patterns of both primary tumour and metastatic tumour in a lymph node. METHODS A retrospective study was conducted in the Department of Pathology, RIMS, Imphal, over a period of one year from January 1, 2018 to December 31, 2018. Five hundred and fifty-five lymph nodes were aspirated, out of which 99 cases turned out to be malignant lesions. Giemsa and PAP stained FNAC slides were collected and reviewed. Data entry and analysis were done by using SPSS version 21. RESULTS Out of 99 cases, 88.9 % were metastatic tumours and 11.1 % were of primary lymphoproliferative disorders. Thirty three percent of malignant lymphadenopathy were found in fifth decade. Undifferentiated carcinoma constituted around 32.3 % of all the cases of malignant lymphadenopathy. Cervical group of lymph nodes were involved in 46.5 % of cases. CONCLUSIONS FNAC has proved to be a useful tool in diagnosing malignancy with good certainty. FNAC of lymph nodes prevents complications associated with lymph node biopsy. KEYWORDS FNAC, Lymph Node, Undifferentiated Carcinoma, Squamous Cell Carcinoma

scholarly journals Fine needle aspiration cytology of palpable supraclavicular lymph nodes

1970 ◽  
Vol 1 (1) ◽  
pp. 8-12
Author(s):  
RC Adhikari ◽  
A Jha ◽  
G Sayami ◽  
G Shrestha ◽  
SK Sharma
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Supraclavicular Lymph Node ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Supraclavicular Lymph Nodes ◽  
Needle Aspiration Cytology

Background: Fine needle aspiration cytology as a first line of investigation has assumed importance in diagnosing a variety of disease process. The aim of this study was to assess the diagnostic value of fine needle aspiration cytology in the evaluation of palpable supraclavicular lymph nodes. Materials and methods: This was a retrospective study of fine needle aspiration cytology of palpable supraclavicular lymph node done between January 1, 2007 and December 31, 2009. Fine needle aspiration cytology was performed on 149 patients (49 cases at Om Hospital & Research Centre and 100 cases at Tribhuvan University Teaching Hospital). Results: The right supraclavicular lymph node was enlarged in 55% cases, while the left supraclavicular lymph node alone was palpable in 40.3% cases and in 7 of 149 (4.7%) cases, bilateral supraclavicular lymph nodes were palpable. Cytological diagnoses were categorized as reactive (8.7%), tuberculosis (41.6%), lymphoma (4.8%) and metastasis (44.9%). Of a total of 74 cases of malignancy, 90.5% were non-lymphoid and 9.5% were lymphoid (5 Non-Hodgkin lymphoma and 2 Hodgkin lymphoma). Of the 67 cases of metastatic disease, three major types of malignancy found in supraclavicular lymph nodes were Squamous cell carcinoma (28 cases), adenocarcinoma (21 cases) and others (small cell carcinoma, papillary thyroid carcinoma etc). Adenocarcinoma tended to metastasize to the left supraclavicular lymph node. Lung was the most common primary site (43.3%), followed by stomach, ovary, breast and larynx. However, in 28.4% cases, no primary site was found. Conclusion: The fine needle aspiration cytology can be used as a first line investigation in the evaluation of supraclavicular lymphadenopathy due to its low cost, simplicity and minimal invasiveness. Keywords: Supraclavicular lymph node; Fine needle aspiration cytology; Metastasis DOI: 10.3126/jpn.v1i1.4441 Journal of Pathology of Nepal (2011) Vol.1, 8-12  

scholarly journals A Case of DisseminatedMycobacterium aviumInfection in a Dog in Greece

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
V. Kontos ◽  
E. I. Papadogiannakis ◽  
G. Mantziaras ◽  
M. Styliara ◽  
S. Kanavaki
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Mycobacterium Avium ◽  
Fine Needle Aspiration ◽  
Bacterial Culture ◽  
Pcr Amplification ◽  
Needle Aspiration ◽  
Molecular Techniques ◽  
Fine Needle ◽  
Pcr Products

A Basset Hound dog was presented with anorexia, fever, diarrhea, significant level of splenomegaly, and enlargement of mesenteric and superficial lymph nodes. Cytology of fine-needle-aspiration material, obtained from popliteal lymph node, revealed macrophages with intracytoplasmic, nonstaining, slender, rod-like structures, indicative of mycobacteria. Bacterial culture of lymph node aspirated material produced a colony which by means of molecular techniques (PCR amplification and hybridization of PCR products) was subsequently identified asMycobacterium avium. This is the first report of disseminatedM. aviuminfection in a dog in Greece.

scholarly journals Significance of ultrasound and ultrasound-guided fine-needle aspiration for the detection of laryngeal occult metastases

2005 ◽  
Vol 62 (12) ◽  
pp. 901-907
Author(s):  
Ljiljana Cvorovic ◽  
Zoran Milutinovic ◽  
Mile Strbac ◽  
Ljubomir Pavicevic ◽  
Alek Racic
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Preoperative Staging ◽  
Needle Aspiration ◽  
University Hospital ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
The Status ◽  
Neck Lymph Nodes

Background/Aim. To evaluate ultrasound criteria based on a node size, shape, vascularity and cytology findings with respect to their value for the comparative determination of metastatic lymph nodes in laryngeal carcinoma. Methods. A prospective study included 30 patients with laryngeal squamous cell carcinoma without node enlargement on computerized tomography, at the Department of Otorhinolaryngology, the University Hospital, Zemun. Thirty-six neck lymph nodes were evaluated sonographically and aspirated with an ultrasound-guided fine-needle. They were examined cytologically and/or histopathologically and compared to the sonographic assessment of their malignancy. Results. Of the 36 neck lymph nodes evaluated cytologically, the 13 were found to be with a metastatic deposit. The assessment of a lymph node malignancy using the parameter of size had the sensitivity of 84%, the specificity of 70%, and the reliability of 75%. Using the criteria of a lymph node shape for the assessment of malignancy, the sensitivity of 61%, specificity of 65%, and the reliability of 64% were achieved. The evaluation of a lymph node vascularity by the use of the effect of Doppler showed the sensitivity of 69%, the specificity of 95%, and the reliability of 86%. Concluson. Ultrasound and ultrasound-guided fine-needle aspiration cytology should be always used for the preoperative staging and for the postoperative follow-up of the status of the neck with cancer of the larynx becouse of their high accuracy, availability and semiinvasivity, and in order to enhance the reliability of the evaluation of the malignant disease progression.

scholarly journals Fine needle aspiration: a simple and handy tool to diagnose malignant lymphadenopathy

2017 ◽  
Vol 5 (9) ◽  
pp. 3949
Author(s):  
Sravani P. ◽  
Neeraja M. ◽  
Bhavani C.
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Radiological Data ◽  
Common Diagnosis ◽  
Malignant Lesions ◽  
Primary Lymph Node ◽  
Needle Aspiration Cytology

Background: Fine needle aspiration cytology (FNAC) of the lymph node is a simple useful screening test to diagnose suspected and unsuspected secondary and primary lymph node malignancy. The aim of the present study is to know the role of FNAC in the diagnosis of clinically suspected and unsuspected lymph node malignancies. Study design: prospective cohort study.Methods: Study material comprise of ‘76’ lymph nodes aspirates reported as malignant on cytology, out of total 445 cases of lymph node aspiration in two years period i.e. from October 2014 to September 2016.These 76 smears were studied and tabulated according to their cytomorphology and the lymph node group affected was noted. The clinical and radiological data were also noted.Results: Males were found more affected than females. cervical lymph node is the commonest group involved. Metastasis from squamous cell carcinoma was the most common diagnosis made on cytology.Conclusions: FNAC is found simple and very useful tool for diagnosing malignant lesions of lymph nodes especially in case of metastasis.

scholarly journals Cystic lymph node metastasis in papillary thyroid carcinoma

Medicina ◽  
2008 ◽  
Vol 44 (6) ◽  
pp. 455 ◽  
Author(s):  
Edita Mišeikytė-Kaubrienė ◽  
Mantas Trakymas ◽  
Albertas Ulys
Keyword(s):  
Lymph Node ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Papillary Thyroid ◽  
Ultrasound Guided ◽  
Fine Needle

Background. Thyroid cancer, especially papillary carcinoma, metastasizes most often into cervical lymph nodes. Cervical ultrasound and ultrasound-guided fine-needle aspiration biopsy are the most sensitive modalities in detecting locoregional neck recurrence. Objective. The aim of this study was to illustrate the ultrasound spectrum of lymph node metastases from papillary thyroid carcinoma. Patients and methods. During 1998–2002 years due to suspicion of recurrence of thyroid cancer, 75 ultrasound-guided fine-needle aspiration biopsies of regional lymph nodes were performed. Ultrasound examination of 75 patients with thyroid cancer (56 women and 19 men; mean age of patients was 54.67±12.89 years) was performed. All biopsies were performed on nonpalpable lesions (lymph node short axis £1.5 cm). Results. A total of 75 ultrasound-guided fine-needle aspiration biopsies of regional lymph nodes under suspicion of malignancy were performed. Only 5 (6.7%) of the 75 lymph nodes were cystic with internal septation. Other 70 (93.3%) lymph nodes were solid. Cytopathological results of 75 ultrasound-guided fine-needle aspiration biopsies from regional cervical lymph nodes were noninformative in 4 (5.3%) cases, benign – 40 (53.4%), suspicion – 4 (5.3%), and malignant – 27 (36.0%) cases. Eighteen patients underwent surgery for regional lymph nodes. All cystic metastases were confirmed to be papillary thyroid carcinoma on pathologic examination. Conclusion. Ultrasound cannot exactly distinguish benign from malign lesions, but sonographic appearance can suggest malignancy and help in selection of the correct lymph nodes to aspirate with ultrasound-guided fine-needle aspiration biopsy. Cystic lymph node metastases may occur in papillary thyroid carcinoma. Cystic neck lesion patients with thyroid papillary carcinoma should always be verified with fine-needle aspiration biopsy.

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