scholarly journals First Report ofNocardia asiaticaPresenting as an Anterior Mediastinal Mass in a Patient with Myasthenia Gravis: A Case Report and Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Rima I. El-Herte ◽  
Souha S. Kanj ◽  
George F. Araj ◽  
Hassan Chami ◽  
Walid Gharzuddine

The spectrum of infections withNocardia spp. is heterogeneous. It has classically been associated with lung, brain, or skin involvement. We describe an unusual presentation ofNocardia asiatica (N. asiatica)in an Iraqi patient with myasthenia gravis suffering from a disseminated infection and presenting with an anterior mediastinal cystic mass.N. asiaticahas only been three times described outside Japan and Thailand, and the rarity of this entity deserves this communication.

2006 ◽  
Vol 130 (2) ◽  
pp. 201-204 ◽  
Author(s):  
Payal Kapur ◽  
Dinesh Rakheja ◽  
Michael Bastasch ◽  
Kyle H. Molberg ◽  
Venetia R. Sarode

Abstract Primary thymic mucinous adenocarcinoma is extremely rare; to our knowledge, only 2 cases have been reported to date. We describe a third case of primary mucinous adenocarcinoma of the thymus in a 41-year-old man who presented with an anterior mediastinal mass with subsequent metastasis to the lung. The initial diagnosis was of metastatic mucinous adenocarcinoma, but extensive clinical workup of the patient failed to reveal a primary tumor elsewhere in the body. The specific identification of mucinous adenocarcinoma as a primary thymic neoplasm can be difficult or impossible. Morphologic and immunophenotypic similarities to mucinous adenocarcinomas of the gastrointestinal tract can pose diagnostic challenges for surgical pathologists, especially in small biopsy specimens.


2021 ◽  
pp. 1-6
Author(s):  
Heleen De Lil ◽  
Michelle van Beek ◽  
Alexandra Herbers ◽  
Ellen van der Holst ◽  
Karen Keijsers

Cerebral infarction as well as other thromboses, headaches, and visual complaints are well-known symptoms of polycythemia vera. However, chorea and neuropsychiatric disturbances are less recognized consequences of this chronic disease. Whereas chorea is a rare but acknowledged symptom of polycythemia vera, neuropsychiatric symptoms have only sporadically been reported. We depict 2 patients with an unusual presentation of polycythemia vera. Our first patient presented with right-sided hemiballism and psychosis, and the second patient had a long diagnostic trajectory of unexplained chorea. In both cases diagnosis of JAK2 positive polycythemia vera was established, and in both cases remarkable recovery occurred after the initiation of phlebotomies. The underlying pathophysiology of these symptoms has not been clearly elucidated. Because of the unfamiliarity of the link between especially neuropsychiatric symptoms and polycythemia, current reported numbers are probably an underestimation. Benefit of treatment appears to be large. We seek to create more awareness among physicians about this phenomenon.


2012 ◽  
Vol 7 (4) ◽  
pp. 179-182 ◽  
Author(s):  
Maria Elena Cavicchiolo ◽  
Paola Berlese ◽  
Silvia Bressan ◽  
Elena Trincia ◽  
Ingrid Inches ◽  
...  

1990 ◽  
Vol 10 (3) ◽  
pp. 293-297 ◽  
Author(s):  
I. M. Al-Fawaz ◽  
S. A. Al-Rasheed ◽  
S. A. Al-Majed ◽  
M. Ashour

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