scholarly journals AnIn SilicoApproach for Evaluating a Fraction-Based, Risk Assessment Method for Total Petroleum Hydrocarbon Mixtures

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Nina Ching Y. Wang ◽  
Glenn E. Rice ◽  
Linda K. Teuschler ◽  
Joan Colman ◽  
Raymond S. H. Yang
Keyword(s):  
Risk Assessment ◽  
Petroleum Hydrocarbon ◽  
Environmental Fate ◽  
Assessment Method ◽  
Total Petroleum Hydrocarbon ◽  
Field Analysis ◽  
Chemical Methods ◽  
Risk Assessment Method ◽  
Risk Of Exposure ◽  
Mixture Risk Assessment

Both the Massachusetts Department of Environmental Protection (MADEP) and the Total Petroleum Hydrocarbon Criteria Working Group (TPHCWG) developed fraction-based approaches for assessing human health risks posed by total petroleum hydrocarbon (TPH) mixtures in the environment. Both organizations defined TPH fractions based on their expected environmental fate and by analytical chemical methods. They derived toxicity values for selected compounds within each fraction and used these as surrogates to assess hazard or risk of exposure to the whole fractions. Membership in a TPH fraction is generally defined by the number of carbon atoms in a compound and by a compound's equivalent carbon (EC) number index, which can predict its environmental fate. Here, we systematically and objectively re-evaluate the assignment of TPH to specific fractions using comparative molecular field analysis and hierarchical clustering. The approach is transparent and reproducible, reducing inherent reliance on judgment when toxicity information is limited. Our evaluation of membership in these fractions is highly consistent (̃80% on average across various fractions) with the empirical approach of MADEP and TPHCWG. Furthermore, the results support the general methodology of mixture risk assessment to assess both cancer and noncancer risk values after the application of fractionation.

Storm surge risk assessment method for a coastal county in China: case study of Jinshan District, Shanghai

2020 ◽  
Vol 34 (5) ◽  
pp. 627-640 ◽  
Author(s):  
Shi Xianwu ◽  
Qiu Jufei ◽  
Chen Bingrui ◽  
Zhang Xiaojie ◽  
Guo Haoshuang ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Storm Surge ◽  
Assessment Method ◽  
Risk Assessment Method ◽  
Coastal County

scholarly journals A Methodology for Harmonizing Safety and Health Scales in Occupational Risk Assessment

2021 ◽  
Vol 18 (9) ◽  
pp. 4849
Author(s):  
Zuzhen Ji ◽  
Dirk Pons ◽  
John Pearse
Keyword(s):  
Risk Assessment ◽  
Health And Safety ◽  
Assessment Method ◽  
Assessment Process ◽  
Successful Implementation ◽  
Health Issues ◽  
Public Health Perspective ◽  
Chronic Health ◽  
Risk Assessment Method

Successful implementation of Health and Safety (H&S) systems requires an effective mechanism to assess risk. Existing methods focus primarily on measuring the safety aspect; the risk of an accident is determined based on the product of severity of consequence and likelihood of the incident arising. The health component, i.e., chronic harm, is more difficult to assess. Partially, this is due to both consequences and the likelihood of health issues, which may be indeterminate. There is a need to develop a quantitative risk measurement for H&S risk management and with better representation for chronic health issues. The present paper has approached this from a different direction, by adopting a public health perspective of quality of life. We have then changed the risk assessment process to accommodate this. This was then applied to a case study. The case study showed that merely including the chronic harm scales appeared to be sufficient to elicit a more detailed consideration of hazards for chronic harm. This suggests that people are not insensitive to chronic harm hazards, but benefit from having a framework in which to communicate them. A method has been devised to harmonize safety and harm risk assessments. The result was a comprehensive risk assessment method with consideration of safety accidents and chronic health issues. This has the potential to benefit industry by making chronic harm more visible and hence more preventable.

An intelligent quantitative risk assessment method for ammonia synthesis process

2021 ◽  
Vol 420 ◽  
pp. 129893
Author(s):  
Zijian Liu ◽  
Wende Tian ◽  
Zhe Cui ◽  
Honglong Wei ◽  
Chuankun Li
Keyword(s):  
Risk Assessment ◽  
Ammonia Synthesis ◽  
Assessment Method ◽  
Quantitative Risk Assessment ◽  
Synthesis Process ◽  
Risk Assessment Method

An immune-based risk assessment method for digital virtual assets

2021 ◽  
Vol 102 ◽  
pp. 102134
Author(s):  
Junjiang He ◽  
Tao Li ◽  
Beibei Li ◽  
Xiaolong Lan ◽  
Zhiyong Li ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Assessment Method ◽  
Risk Assessment Method

scholarly journals Absolute mortality risk assessment of COVID-19 patients: the Khorshid COVID Cohort (KCC) study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hamid Reza Marateb ◽  
Maja von Cube ◽  
Ramin Sami ◽  
Shaghayegh Haghjooy Javanmard ◽  
Marjan Mansourian ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Hospital Admission ◽  
Mortality Risk ◽  
Regression Models ◽  
Assessment Method ◽  
Point Of View ◽  
Statistical Point ◽  
Hazard Regression ◽  
Risk Assessment Method ◽  
Discharge From Hospital

Abstract Background Already at hospital admission, clinicians require simple tools to identify hospitalized COVID-19 patients at high risk of mortality. Such tools can significantly improve resource allocation and patient management within hospitals. From the statistical point of view, extended time-to-event models are required to account for competing risks (discharge from hospital) and censoring so that active cases can also contribute to the analysis. Methods We used the hospital-based open Khorshid COVID Cohort (KCC) study with 630 COVID-19 patients from Isfahan, Iran. Competing risk methods are used to develop a death risk chart based on the following variables, which can simply be measured at hospital admission: sex, age, hypertension, oxygen saturation, and Charlson Comorbidity Index. The area under the receiver operator curve was used to assess accuracy concerning discrimination between patients discharged alive and dead. Results Cause-specific hazard regression models show that these baseline variables are associated with both death, and discharge hazards. The risk chart reflects the combined results of the two cause-specific hazard regression models. The proposed risk assessment method had a very good accuracy (AUC = 0.872 [CI 95%: 0.835–0.910]). Conclusions This study aims to improve and validate a personalized mortality risk calculator based on hospitalized COVID-19 patients. The risk assessment of patient mortality provides physicians with additional guidance for making tough decisions.

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