scholarly journals Interaction between Chronic Inflammation and Oral HPV Infection in the Etiology of Head and Neck Cancers

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Mine Tezal
Keyword(s):  
Head And Neck ◽  
Chronic Inflammation ◽  
Potential Role ◽  
Hpv Infection ◽  
Oral Tongue ◽  
Papillomavirus Infection ◽  
Prevention And Treatment ◽  
Oral Hpv ◽  
Base Of The Tongue

Incidences of oral tongue, base of the tongue, and tonsil cancers have been increasing steadily in many parts of the world in spite of declining rates of tobacco use over the last four decades. A better understanding of the etiology, interactions between risk factors, and new approaches to prevention and treatment are necessary to change this course. This paper will present evidence supporting a potential role of chronic inflammation in the etiologies of oral human papillomavirus infection and head and neck squamous cell carcinoma, and it will discuss the implications for prevention and treatment.

scholarly journals COVID-19: Up to 82% critically ill patients had low Vitamin C values

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Teresa Maria Tomasa-Irriguible ◽  
Lara Bielsa-Berrocal
Keyword(s):  
Vitamin C ◽  
Critically Ill ◽  
Potential Role ◽  
Plasma Vitamin ◽  
Single Center ◽  
Berlin Definition ◽  
Single Center Study ◽  
Prevention And Treatment ◽  
Center Study

AbstractThere are limited proven therapeutic options for the prevention and treatment of COVID-19. We underwent an observational study with the aim of measure plasma vitamin C levels in a population of critically ill COVID-19 adult patients who met ARDS criteria according to the Berlin definition. This epidemiological study brings to light that up to 82% had low Vitamin C values. Notwithstanding the limitation that this is a single-center study, it nevertheless shows an important issue. Given the potential role of vitamin C in sepsis and ARDS, there is gathering interest of whether supplementation could be beneficial in COVID-19.

Potential role of micro-RNAs in head and neck tumorigenesis

Head & Neck ◽  
2010 ◽  
Vol 32 (8) ◽  
pp. 1099-1111 ◽  
Author(s):  
Nham Tran ◽  
Christopher J. O'Brien ◽  
Jonathan Clark ◽  
Barbara Rose
Keyword(s):  
Head And Neck ◽  
Potential Role ◽  
Micro Rnas

scholarly journals Ultraviolet Radiation and Chronic Inflammation—Molecules and Mechanisms Involved in Skin Carcinogenesis: A Narrative Review

Life ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 326
Author(s):  
Magdalena Ciążyńska ◽  
Irmina Olejniczak-Staruch ◽  
Dorota Sobolewska-Sztychny ◽  
Joanna Narbutt ◽  
Małgorzata Skibińska ◽  
...  
Keyword(s):  
Ultraviolet Radiation ◽  
Chronic Inflammation ◽  
Potential Role ◽  
Tumor Formation ◽  
Skin Carcinogenesis ◽  
Molecular Networks ◽  
Cancer Therapies ◽  
Inflammatory Microenvironment ◽  
Skin Cancers

The process of skin carcinogenesis is still not fully understood. Both experimental and epidemiological evidence indicate that chronic inflammation is one of the hallmarks of microenvironmental-agent-mediated skin cancers and contributes to its development. Maintaining an inflammatory microenvironment is a condition leading to tumor formation. Multiple studies focus on the molecular pathways activating tumorigenesis by inflammation and indicate several biomarkers and factors that can improve diagnostic and prognostic processes in oncology and dermatology. Reactive oxygen species produced by ultraviolet radiation, oxidizers, or metabolic processes can damage cells and initiate pro-inflammatory cascades. Considering the potential role of inflammation in cancer development and metastasis, the identification of early mechanisms involved in carcinogenesis is crucial for clinical practice and scientific research. Moreover, it could lead to the progress of advanced skin cancer therapies. We focus on a comprehensive analysis of available evidence and on understanding how chronic inflammation and ultraviolet radiation can result in skin carcinogenesis. We present the inflammatory environment as complex molecular networks triggering tumorigenesis and constituting therapeutic targets.

scholarly journals Oral HPV infection and persistence in patients with head and neck cancer

2013 ◽  
Vol 116 (4) ◽  
pp. 474-484 ◽  
Author(s):  
Patrizia Morbini ◽  
Barbara Dal Bello ◽  
Paola Alberizzi ◽  
Laura Mannarini ◽  
Niccolò Mevio ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Hpv Infection ◽  
Oral Hpv

Stem Cells from Human Exfoliated Deciduous Teeth and their Promise as Preventive and Therapeutic Strategies for Neurological Diseases and Injuries

2021 ◽  
Vol 17 ◽  
Author(s):  
Lingyi Huang ◽  
Zizhuo Zheng ◽  
Ding Bai ◽  
Xianglong Han
Keyword(s):  
Stem Cells ◽  
Potential Role ◽  
Neurological Diseases ◽  
Therapeutic Strategies ◽  
Deciduous Teeth ◽  
Research Attention ◽  
Considerable Potential ◽  
Prevention And Treatment ◽  
Human Exfoliated Deciduous Teeth

Abstract: Stem cells from human exfoliated deciduous teeth (SHEDs) are relatively easy to isolate from exfoliated deciduous teeth, which are obtained via dental therapy as biological waste. SHEDs originate from the embryonic neural crest and therefore have considerable potential for neurogenic differentiation. Currently, an increasing amount of research attention is focused on the therapeutic applications of SHEDs in neurological diseases and injuries. In this article, we summarize the biological characteristics of SHEDs and the potential role of SHEDs and their derivatives, including conditioned medium from SHEDs and the exosomes they secrete, in the prevention and treatment of neurological diseases and injuries.

Potential role of lipoic acid as a chelator in prevention and treatment of gadolinium brain retention

2018 ◽  
Vol 114 ◽  
pp. 29
Author(s):  
Ashkan Heshmatzadeh Behzadi ◽  
Ajay Gupta ◽  
Martin R. Prince
Keyword(s):  
Lipoic Acid ◽  
Potential Role ◽  
Prevention And Treatment
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