scholarly journals Clinical Outcomes of the Marginal Ulcer Bleeding after Gastrectomy: As Compared to the Peptic Ulcer Bleeding with Nonoperated Stomach

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Woo Chul Chung ◽  
Eun Jung Jeon ◽  
Kang-Moon Lee ◽  
Chang Nyol Paik ◽  
You Suk Oh ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Clinical Outcomes ◽  
Marginal Ulcer ◽  
Ulcer Bleeding ◽  
Consecutive Series ◽  
Peptic Ulcer Bleeding ◽  
Positive Rate ◽  
Rebleeding Rate ◽  
H Pylori ◽  
Upper Gastrointestinal

Background. Marginal ulcer is a well-known complication after gastrectomy. Its bleeding can be severe, but the severity has rarely been reported. We aim to evaluate the clinical outcomes of marginal ulcer bleeding (MUB) as compared to peptic ulcer bleeding (PUB) with nonoperated stomach.Methods. A consecutive series of patients who had nonvariceal upper gastrointestinal bleeding and admitted to the hospital between 2005 and 2011 were retrospectively analyzed. A total of 530 patients were enrolled in this study, and we compared the clinical characteristics between 70 patients with MUB and 460 patients with PUB.Results. Patients with MUB were older (mean age:62.86±10.59years versus53.33±16.68years,P=0.01). The initial hemoglobin was lower (8.16±3.05 g/dL versus9.38±2.49 g/dL,P=0.01), and the duration of admission was longer in MUB (7.14±4.10days versus5.90±2.97days,P=0.03). After initial hemostasis, the rebleeding rate during admission was higher (16.2% versus 6.5%,P=0.01) in MUB. However, the mortality rate did not differ statistically between MUB and PUB groups.Helicobacter pylori-positive rate with MUB was lower than that of PUB (19.4% versus 54.4%,P=0.01).Conclusions. Clinically, MUB after gastrectomy is more severe than PUB with nonoperated stomach. Infection withH. pylorimight not appear to play an important role in MUB after gastrectomy.

scholarly journals Early Diagnosis of Helicobacter pylori Infection in Vietnamese Patients with Acute Peptic Ulcer Bleeding: A Prospective Study

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Duc Trong Quach ◽  
Mai Ngoc Luu ◽  
Toru Hiyama ◽  
Thuy-HuongThi To ◽  
Quy Nhuan Bui ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Infection Rate ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding ◽  
Urease Test ◽  
Positive Rate ◽  
Group A ◽  
H Pylori ◽  
Group B ◽  
Noninvasive Tests

Aims. To investigate H. pylori infection rate and evaluate a combined set of tests for H. pylori diagnosis in Vietnamese patients with acute peptic ulcer bleeding (PUD). Methods. Consecutive patients with acute PUB were enrolled prospectively. Rapid urease test (RUT) with 3 biopsies was carried out randomly. Patients without RUT or with negative RUT received urea breath test (UBT) and serological and urinary H. pylori antibody tests. H. pylori was considered positive if RUT or any noninvasive test was positive. Patients were divided into group A (RUT plus noninvasive tests) and group B (only noninvasive tests). Results. The overall H. pylori infection rate was 94.2% (161/171). Groups A and B had no differences in demographic characteristics, bleeding severity, endoscopic findings, and proton pump inhibitor use. H. pylori-positive rate in group A was significantly higher than that in group B (98.2% versus 86.7%, p=0.004). The positive rate of RUT was similar at each biopsy site but significantly increased if RUT results from 2 or 3 sites were combined (p<0.05). Conclusions. H. pylori infection rate in Vietnamese patients with acute PUB is high. RUT is an excellent test if at least 2 biopsies are taken.

Will Helicobacter Pylori Affect Short-Term Rebleeding Rate in Peptic Ulcer Bleeding Patients After Successful Endoscopic Therapy?

1999 ◽  
Vol 94 (11) ◽  
pp. 3184-3188 ◽  
Author(s):  
Hwai-Jeng Lin ◽  
Guan-Ying Tseng ◽  
Yu-Hsi Hsieh ◽  
Chin-Lin Perng ◽  
Fa-Yauh Lee ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Endoscopic Therapy ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding ◽  
Short Term ◽  
Rebleeding Rate

Effect of intravenous proton pump inhibitor regimens and timing of endoscopy on clinical outcomes of peptic ulcer bleeding

2012 ◽  
Vol 27 (9) ◽  
pp. 1473-1479 ◽  
Author(s):  
Na Liu ◽  
Lili Liu ◽  
HongBo Zhang ◽  
Prakash Chandra Gyawali ◽  
Dexin Zhang ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Proton Pump Inhibitor ◽  
Clinical Outcomes ◽  
Proton Pump ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding

Testing for and eradication of H. pylori infection is inadequately performed in patients with peptic ulcer bleeding

2001 ◽  
Vol 120 (5) ◽  
pp. A729-A729
Author(s):  
D THORBURN ◽  
C OCONNOR ◽  
E FORREST ◽  
J FORREST
Keyword(s):  
Peptic Ulcer ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding ◽  
H Pylori

scholarly journals Advances in the Therapy of Bleeding Peptic Ulcer

2018 ◽  
Vol 10 ◽  
pp. 1179559X1879025 ◽  
Author(s):  
Ian LP Beales
Keyword(s):  
Peptic Ulcer ◽  
Accurate Determination ◽  
Medical Emergency ◽  
Ulcer Bleeding ◽  
Peptic Ulcers ◽  
Doppler Probe ◽  
Bleeding Peptic Ulcers ◽  
Risk Patients ◽  
Rebleeding Rate ◽  
H Pylori

Peptic ulcer bleeding remains an important medical emergency. Important recent advances are reviewed. These include further support for a more restrictive transfusion strategy aiming for a target haemoglobin of 70-90 g/L. The Glasgow-Blatchford score remains the most useful assessment score for identifying the lowest risk patients suitable for outpatient management and predicting the need for intervention. Newer scores such as the AIMS65 and Progetto Nazionale Emorragia Digestive score (PNED) may be more accurate in predicting mortality. Pre-endoscopy erythromycin improves outcomes and is underused. A new disposable Doppler probe appears to provide more accurate determination of both rebleeding risk and the success of endoscopic therapy than purely visual guidance. Over-the-scope clips and haemostatic powders appear to have some role as endoscopic salvage therapies. Non- H. pylori, non-aspirin/non-steroidal anti-inflammatory drug (NSAID) ulcers contribute to an increasing percentage of bleeding peptic ulcers and are associated with a high rebleeding rate. The optimal management of these ulcers remains to be determined.

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